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Acta Oto-Laryngologica Volume 139, 2019 - Issue 3
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Research Article

The prognostic value of preoperative derived neutrophil-to-lymphocyte ratio in patients undergoing total laryngectomy with laryngeal carcinoma

Shenghua SongDepartment of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, ChinaView further author information
,
Huijun ChenDepartment of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, ChinaView further author information
,
Weida DongDepartment of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, ChinaView further author information
&
Han ZhouDepartment of Otorhinolaryngology, The First Affiliated Hospital, Nanjing Medical University, Nanjing, ChinaCorrespondence[email protected]
View further author information
Pages 294-298 | Received 18 Nov 2018, Accepted 03 Jan 2019, Published online: 18 Mar 2019

References

  • Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420:860–867.
  • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144:646–674.
  • Proctor MJ, McMillan DC, Morrison DS, et al. A derived neutrophil to lymphocyte ratio predicts survival in patients with cancer. Br J Cancer. 2012;107:695–699.
  • Templeton AJ, McNamara MG, Šeruga B, et al. Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis. J Natl Cancer Inst. 2014;106:dju124.
  • Farrow B, Sugiyama Y, Chen A, et al. Inflammatory mechanisms contributing to pancreatic cancer development. Ann Surg. 2004;239:763–771.
  • Grimm M, Rieth J, Hoefert S, et al. Standardized pretreatment inflammatory laboratory markers and calculated ratios in patients with oral squamous cell carcinoma. Eur Arch Otorhinolaryngol. 2016;273:3371–3384.
  • Vikram B, Strong EW, Shah JP, et al. Failure at the primary site following multimodality treatment in advanced head and neck cancer. Head Neck Surg. 1984;6:720–723.
  • Gregory AD, Houghton AM. Tumor-associated neutrophils: new targets for cancer therapy. Cancer Res. 2011;71:2411–2416.
  • Tazzyman S, Lewis CE, Murdoch C. Neutrophils: key mediators of tumour angiogenesis. Int J Exp Pathol. 2009;90:222–231.
  • Ruffell B, DeNardo DG, Affara NI, et al. Lymphocytes in cancer development: polarization towards pro-tumor immunity. Cytokine Growth Factor Rev. 2010;21:3–10. [PubMed: 20005150.
  • Smith HA, Kang Y. The metastasis-promoting roles of tumor-associated immune cells. J Mol Med. 2013;91:411–429.
  • Jain S, Harris J, Ware J. Platelets: linking hemostasis and cancer. Arterioscler Thromb Vasc Biol. 2010;30:2362–2367.
  • Walsh SR, Cook EJ, Goulder F, et al. Neutrophil-lymphocyte ratio as a prognostic factor in colorectal cancer. J Surg Oncol. 2005;91:181–184.
  • Cho H, Hur Hye W, Kim SW, et al. Pre-treatment neutrophil to lymphocyte ratio is elevated in epithelial ovarian cancer and predicts survival after treatment. Cancer Immunol Immunother. 2009;58:15–23.
  • Fu Yan, Liu W, OuYang D, et al. Preoperative neutrophil-to-lymphocyte ratio predicts long-term survival in patients undergoing total laryngectomy with advanced laryngeal squamous cell carcinoma: a single-center retrospective study. Medicine (Baltimore). 2016;95:e2689.
  • Basem A, Neeraj S, Jared R, et al. Pretreatment neutrophil/lymphocyte ratio is superior to platelet/lymphocyte ratio as a predictor of long-term mortality in breast cancer patients. Med Oncol. 2013;30:432.
  • Ozmen S, Timur O, Calik I, et al. Neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) may be superior to C-reactive protein (CRP) for predicting the occurrence of differentiated thyroid cancer. Endocr Regul. 2017;51:131–136.
  • Grenader T, Nash S, Adams R, et al. Derived neutrophil lymphocyte ratio is predictive of survival from intermittent therapy in advanced colorectal cancer: a post hoc analysis of the MRC COIN study. Br J Cancer. 2016;114:612–615.
  • Szkandera J, Stotz M, Eisner F, et al. External validation of the derived neutrophil to lymphocyte ratio as a prognostic marker on a large cohort of pancreatic cancer patients. PLoS One. 2013;8:e78225.

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