References
- Müller U, Barr-Gillespie PG. New treatment options for hearing loss. Nat Rev Drug Discov. 2015;14:346–365.
- Akil O, Rouse SL, Chan DK, et al. Surgical method for virally mediated gene delivery to the mouse inner ear through the round window membrane. J Vis Exp. 2015;97:1–7.
- Devare J, Gubbels S, Raphael Y. Outlook and future of inner ear therapy. Hear Res. 2018;368:127–135.
- Ahmed H, Hubina-Oleinik O, Holt J. Emerging gene therapies for genetic hearing loss. J Assoc Res Otolaryngol. 2017;18:649–670.
- Chien WW, Monzack EL, McDougald DS, et al. Gene therapy for sensorineural hearing loss. Ear Hear. 2015;36:1–7.
- Glueckert R, Johnson Chacko L, Rask-Andersen H, et al. Anatomical basis of drug delivery to the inner ear. Hear Res. 2018;368:10–27.
- Isgrig K, Chien WW. Posterior semicircular canal approach for inner ear gene delivery in neonatal mouse. J Vis Exp. 2018;133:1–5.
- Isgrig K, McDougald DS, Zhu J, et al. AAV2.7m8 is a powerful viral vector for inner ear gene therapy. Nat Commun. 2019;10:427.
- Tao Y, Huang M, Shu Y, et al. Delivery of adeno-associated virus vectors in adult mammalian inner-ear cell subtypes without auditory dysfunction. Hum Gene Ther. 2018;29:492–506.
- Guo W, Yi H, Ren L, et al. The morphology and electrophysiology of the cochlea of the miniature pig. Anat Rec (Hoboken). 2015;298:494–500.
- Guo W, Yang S. Advantages of a miniature pig model in research on human hereditary hearing loss. J Otol. 2015;10:105–107.
- Hai T, Guo W, Yao J, et al. Creation of miniature pig model of human Waardenburg syndrome type 2A by ENU mutagenesis. Hum Genet. 2017;136:1463–1475.
- Askew C, Rochat C, Pan B, et al. Tmc gene therapy restores auditory function in deaf mice. Sci Transl Med. 2015;7:295ra108.
- Gao X, Tao Y, Lamas V, et al. Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. Nature. 2018;553:217–221.
- Isgrig K, Shteamer JW, Belyantseva IA, et al. Gene therapy restores balance and auditory functions in a mouse model of Usher syndrome. Mol Ther. 2017;25:780–791.
- Yi HJ, Guo W, Wu N, et al. The temporal bone microdissection of miniature pigs as a useful large animal model for otologic research. Acta Otolaryngol. 2014;134:26–33.
- Guo JY, He L, Qu TF, et al. Canalostomy as a surgical approach to local drug delivery into the inner ears of adult and neonatal mice. J Vis Exp. 2018;135:1–8.
- Landegger LD, Pan B, Askew C, et al. A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear. Nat Biotechnol. 2017;35:280–284.
- Shi X, Wu N, Zhang Y, et al. Adeno-associated virus transformation into the normal miniature pig and the normal guinea pigs cochlea via scala tympani. Acta Otolaryngol. 2017;137:910–916.
- Guo JY, Liu YY, Qu TF, et al. Cochleovestibular gene transfer in neonatal mice by canalostomy. Neuroreport. 2017;28:682–688.