References
- Teng ZP, Tian R, Xing FL, et al. An association of type 1 diabetes mellitus with auditory dysfunction: a systematic review and meta-analysis. Laryngoscope. 2017;127(7):1689–1697.
- Akinpelu OV, Mujica-Mota M, Daniel SJ. Is type 2 diabetes mellitus associated with alterations in hearing? A systematic review and meta-analysis. Laryngoscope. 2014;124(3):767–776.
- D'Silva LJ, Lin J, Staecker H, et al. Impact of diabetic complications on balance and falls: contribution of the vestibular system. Phys Ther. 2016;96(3):400–409.
- Elangovan S, Spankovich C. Diabetes and auditory-vestibular pathology. Semin Hear. 2019;40(4):292–299.
- Seo M, Lee YS, Moon SS. Association of hearing impairment with insulin resistance, β-cell dysfunction and impaired fasting glucose before onset of diabetes. Diabet Med. 2016;33(9):1275–1282.
- Hong BN, Kang TH. Distinction between auditory electrophysiological responses in type 1 and type 2 diabetic animal models. Neurosci Lett. 2014;566:309–314.
- Pålbrink AK, Kopietz F, Morén B, et al. Inner ear is a target for insulin signaling and insulin resistance: evidence from mice and auditory HEI-OC1 cells. BMJ Open Diab Res Care. 2020;8(1):e000820.
- Degerman E, Rauch U, Lindberg S, et al. Expression of insulin signalling components in the sensory epithelium of the human saccule. Cell Tissue Res. 2013;352(3):469–478.
- Degerman E, In 't Zandt R, Pålbrink A, et al. Inhibition of phosphodiesterase 3, 4, and 5 induces endolymphatic hydrops in mouse inner ear, as evaluated with repeated 9.4T MRI. Acta Otolaryngol. 2017;137(1):8–15.
- Kim SH, Marcus DC. Regulation of sodium transport in the inner ear. Hear Res. 2011;280(1–2):21–29.
- Rotin D, Staub O. Function and regulation of the epithelial Na+ channel ENaC. Compr Physiol. 2021;11(3):2017–2045.
- Mansley MK, Wilson SM. Effects of nominally selective inhibitors of the kinases PI3K, SGK1 and PKB on the insulin-dependent control of epithelial Na + absorption. Br J Pharmacol. 2010;161(3):571–588.
- Inglis SK, Gallacher M, Brown SG, et al. SGK1 activity in Na + absorbing airway epithelial cells monitored by assaying NDRG1-Thr346/356/366 phosphorylation. Pflugers Arch. 2009;457(6):1287–1301.
- Gleason CE, Frindt G, Cheng CJ, et al. mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity. J Clin Invest. 2015;125(1):117–128.
- Mattes C, Laube M, Thome UH. Rapid elevation of sodium transport through insulin is mediated by AKT in alveolar cells. Physiol Rep. 2014;2(3):e00269.
- Sokolowska E, Blachnio-Zabielska A. The role of ceramides in insulin resistance. Front Endocrinol . 2019;10:577.
- Romero-Guevara R, Cencetti F, Donati C, et al. Sphingosine 1-phosphate signaling pathway in inner ear biology. Front Aging Neurosci. 2015;7:60.
- Kalinec GM, Webster P, Lim DJ, et al. A cochlear cell line as an in vitro system for drug ototoxicity screening. Audiol Neurootol. 2003;8(4):177–189.
- Snyder PM, Olson DR, Kabra R, et al. cAMP and serum and glucocorticoid-inducible kinase (SGK) regulate the epithelial Na(+) channel through convergent phosphorylation of Nedd4-2. J Biol Chem. 2004;279(44):45753–45758.
- Gleason CE, Oses-Prieto JA, Li KH, et al. Phosphorylation at distinct subcellular locations underlies specificity in mTORC2-mediated activation of SGK1 and akt. J Cell Sci. 2019;132(7):jcs224931.