Reversed–Phase Liquid Chromatographic Determination of Zaleplon in Human Plasma and its Pharmacokinetic Application

References

• Ancoli‐Israel , S. , Walsh , J. K. , Mangano , R. M. and Fujimori , M. 1999 . Zaleplon, a novel nonbenzodiazepine hypnotic, effectively treats insomnia in elderly patients without causing rebound effects . Prim. Care Companion J. Clin. Psychiatry. , 1 ( 4 ) : 114 – 120 .
   PubMedGoogle Scholar
• Ashton , C. H. 2003 . “ Insomnia and anxiety ” . In Clinical Pharmacy and Therapeutics , 3rd Ed. Edited by: Walker , R. and Edwards , C. UK : Churchill Livingstone .
   Google Scholar
• Charney , D. S. , Mihic , S. J. and Harris , R. A. 2001 . “ Hypnotics and sedatives ” . In Goodman & Gilman's The Pharmacological Basis of Therapeutics , 10th Edited by: Hardman , J. G. , Limbird , L. E. and Gilman , A. G. USA : McGraw‐Hill .
   Google Scholar
• Dooley , M. and Plosker , G. L. 2000 . Zaleplon: a review of its use in the treatment of insomnia . Drugs , 60 ( 2 ) : 413 – 445 .
   PubMed Web of Science ®Google Scholar
• Drover , D. R. 2004 . Comparative pharmacokinetics and pharmacodynamics of short acting hypnosedatives: zaleplon, zolpidem and zoplicone . Clin.Pharmacokinet. , 43 ( 4 ) : 227 – 238 .
   PubMedGoogle Scholar
• Elie , R. , Ruther , E. , Farr , I. , Emielen , G. and Salinas , E. 1999 . Sleep latency is shortened during four weeks of treatment with zaleplon, a novel non benzodiazepine hypnotic . J. Clin. Psychiatry , 60 ( 8 ) : 536 – 544 .
   PubMed Web of Science ®Google Scholar
• Feng , F. , Jiang , J. , Dai , H. and Wu , J. 2003 . Development and validation of a high‐performance liquid chromatography‐electrospray ionization‐mass spectrometry assay for the determination of zaleplon in human plasma . J. Chromatogr Sci. , 41 ( 1 ) : 17 – 21 .
   PubMedGoogle Scholar
• Fry , J. , Scharf , M. , Mangano , R. and Fujimori , M. 2000 . Zaleplon improves sleep without producing rebound effects in outpatients with insomnia . Int. Clin. Psychopharmacol. , 15 ( 3 ) : 141 – 152 .
   PubMedGoogle Scholar
• Giroud , C. , Augsburger , M. , Menetrey , A. and Mangin , P. 2003 . Determination of zaleplon and zolpidem by liquid chromatograohy‐turbo‐ionspray mass spectrometry: application to forensic medicine . J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. , 789 ( 1 ) : 131 – 138 .
   PubMedGoogle Scholar
• Horstkotter , C. , Schepmann , D. and Blaschke , G. 2003 . Separation and identification of zaleplon metabolites in human urine using capillary electrohoresis with laser‐induced fluorescence detection and liquid chromatography‐mass spectrometry . J. Chromatogr. A , 1014 ( 1–2 ) : 71 – 81 .
   PubMedGoogle Scholar
• Lake , B. G. , Ball , S. E. , Kao , J. , Renwick , A. B. , Price , R. J. and Scatina , J. A. 2002 . Metabolism of zaleplon by human liver: evidence for involvement of aldehyde oxidase . Xenobiotica , 32 ( 10 ) : 835 – 847 .
   PubMed Web of Science ®Google Scholar
• Mitler , M. M. 2000 . Non selective and selective benzodiazepine receptor agonists‐where are we today? . Sleep , 23 ( suppl1 ) : S39 – S47 .
   Google Scholar
• Patat , A. , Patty , I. and Hindmarch , I. 2001 . Pharmacodynamic profile of zaleplon, a new non‐benzodiazepine hypnotic agent . Human Psychopharmacol. , 16 ( 5 ) : 369 – 392 .
   PubMedGoogle Scholar
• Rosen , A. S. , Fournie , P. , Darwish , M. , Danjou , P. and Troy , S. M. 1999 . Zaleplon pharmacokinetics and absolute bioavailability . Biopharm. Drug Dispos. , 20 ( 3 ) : 171 – 175 .
   PubMed Web of Science ®Google Scholar
• Wagner , J. and Wagner , M. L. 2000 . Non benzodiazepines for the treatment of insomnia . Sleep Med. Rev. , 4 ( 6 ) : 551 – 581 .
   PubMed Web of Science ®Google Scholar
• Walsh , J. K. , Vogel , G. W. , Schart , M. , Erman , M. , Erwin , C. W. , Schweitzer , P. K. , Mangano , R. M. and Roth , T. 2000 . A five week, polysomnographic assessment of zaleplon 10 mg for the treatment of primary insomnia . Sleep Med. , 1 : 41 – 49 .
   PubMed Web of Science ®Google Scholar
• Weitzel , K. W. , Wickman , J. M. , Augustin , S. G. and Strom , J. G. 2000 . Zaleplon: a pyrazolopyrimidine sedative‐hypnotic agent for the treatment of insomnia . Clin. Ther. , 22 ( 11 ) : 1254 – 1267 .
   PubMed Web of Science ®Google Scholar