Simple Rapid Validated RP-LC Method for the Estimation of Flurbiprofen in Rabbit Serum and Aqueous Humor

REFERENCES

• Albert , K.S. , Gillespie , W.R. , Raabe , A. , and Garry , M. 1984 . Determination of flurbiprofen in human serum by reverse-phase high-performance liquid chromatography with fluorescence detection . J. Pharm. Sci. , 73 ( 12 ): 1823 – 1825 .
   PubMed Web of Science ®Google Scholar
• Appiotti , A. , Gualdi , L. , Alberti , M. , and Gualdi , M. 1998 . Comparative study of the analgesic efficacy of flurbiprofen and diclofenac in patients following excimer laser photorefractive keratectomy . Clin. Ther. , 20 ( 5 ): 913 – 920 .
   PubMed Web of Science ®Google Scholar
• Askholt , J. and Nielsen-Kudsk , F. 1986 . Rapid HPLC-determination of ibuprofen and flurbiprofen in plasma for therapeutic drug control and pharmacokinetic applications . Acta. Pharmacol. Toxicol. (Copenh.) , 59 ( 5 ): 382 – 386 .
   PubMedGoogle Scholar
• Beaulieu , N. , Cyr , T.D. , and Lovering , E.G. 1991 . Validation of methods for the assay of flurbiprofen and flurbiprofen sodium, related compounds and volatile impurities in raw materials and tablets . Drug Dev. Ind. Pharm. , 17 ( 13 ): 1843 – 1855 .
   Web of Science ®Google Scholar
• Bolton , S. 1997 . Pharmaceutical Statistics: Practical and Clinical Application, , 3rd ed. New York : Marcel Dekker .
   Google Scholar
• Brägger , U. , Mühle , T. , Fourmousis , I. , Lang , N.P. , and Mombelli , A. 1997 . Effect of the NSAID flurbiprofen on remodelling after periodontal surgery . J. Periodontal Res. , 32 ( 7 ): 575 – 582 .
   PubMedGoogle Scholar
• British Pharmacoepia (BP) . 1998 . London : British Pharmacoepia Commission , pp. 612 – 613 .
   Google Scholar
• Diestelhorst , M. , Schmidl , B. , Konen , W. , Mester , U. , and Raj , P.S. 1996 . Efficacy and tolerance ofdiclofenac sodium 0.1%, flurbiprofen 0.03%, and indomethacin 1.0% in controlling postoperative inflammation . J. Cataract Refract. Surg. , 22 (Suppl. 1) : 788 – 793 .
   PubMedGoogle Scholar
• Geisslinger , G. , Menzel-Soglowek , S. , Schuster , O. , and Brune , K. 1992 . Stereoselective high-performance liquid chromatographic determination of flurbiprofen inhuman plasma . J. Chromatogr. , 573 ( 1 ): 163 – 167 .
   PubMedGoogle Scholar
• Giagoudakis , G. and Markantonis , S.L. 1998 . An alternative high-performance liquid-chromatographic method for the determination of diclofenac and flurbiprofen in plasma . J. Pharm. Biomed. Anal. , 17 : 897 – 901 .
   PubMed Web of Science ®Google Scholar
• Hirai , T. , Matsumoto , S. , and Kishi , I. 1997 . Simultaneous analysis of several non-steroidal anti-inflammatory drugs in human urine by high-performance liquid chromatography with normal solid-phase extraction . J. Chromatogr. B: Biomed. Sci. Appl. , 692 ( 2 ): 375 – 388 .
   PubMed Web of Science ®Google Scholar
• Hofer , M. , Pospfsil , M. , and Pipalova , I. 1996 . Radioprotective effects of flurbiprofen . Folia Biol. (Praha) , 42 : 267 – 269 .
   PubMed Web of Science ®Google Scholar
• Hutzler , J.M. , Fyre , R.F. , and Tracy , T.S. 2000 . Sensitive and specific high-performance liquid chromatographic assay for 4′-hydroxyflurbiprofen and flurbiprofen in human urine and plasma . J. Chromatogr. B: Biomed. Sci. Appl. , 749 ( 1 ): 119 – 125 .
   PubMedGoogle Scholar
• Indian Pharmacoepia (IP) . 1996 . New Delhi : Indian Pharmacoepial Commission , pp. 328 – 329 .
   Google Scholar
• International Conference on Harmonisation (ICH) . 1996 . Technical Requirements for Registration of Pharmaceuticals for Human Use: Harmonised Tripartite Guideline on Validation of Analytical Procedures: Methodology . Switzerland : Recommended for adoption at Step 4 of the ICH Process, by the ICH Steering Committee. IFPMA.
   Google Scholar
• Johnson , V.A. and Wilson , J.T. 1986 . Flurbiprofen analysis in plasma and breast milk by high-performance liquid chromatography . J. Chromatogr. B: Biomed. Sci. Appl. , 382 : 372 – 376 .
   Google Scholar
• Jones , D.S. , Irwin , C.R. , Woolfson , A.D. , Djokic , J. , and Adams , V. 1999 . Physicochemical characterization and preliminary in vivo efficacy of bioadhesive, semisolid formulations containing flurbiprofen for the treatment of gingivitis . J. Pharm. Sci. , 88 ( 6 ): 592 – 598 .
   PubMed Web of Science ®Google Scholar
• Juchelková , L. , Hofer , M. , Pospísil , M. , and Pipalová , I. 1998 . Radioprotective effects of flurbiprofen and its nitroderivative . Physiol. Res. , 47 ( 1 ): 73 – 80 .
   PubMedGoogle Scholar
• Knadler , M.P. and Hall , S.D. 1989 . High-performance liquid chromatographic analysis of the enantiomers of flurbiprofen and its metabolites in plasma and urine . J. Chromatogr. B: Biomed. Sci. Appl. , 494 : 173 – 182 .
   Google Scholar
• Mathew , M. , Gupta , V.D. , and Bethea , C. 1993 . Quantitation of flurbiprofen in tablets using high performance liquid chromatography . Drug Dev. Ind. Pharm. , 19 ( 4 ): 493 – 498 .
   Web of Science ®Google Scholar
• McCracken , J.D. , Wechter , W.J. , Liu , Y. , Chase , R.L. , Kantoci , D. , Murray , E.D. Jr. , Quiggle , D.D. , and Mineyama , Y. 1996 . Antiproliferative effects of the enantiomers of flurbiprofen . J. Clin. Pharmacol. , 36 ( 6 ): 540 – 545 .
   PubMedGoogle Scholar
• Pe'hourcq , F. , Jarry , C. , Bannwarth , B. 2001 . Chiral resolution of flurbiprofen and ketoprofen enantiomers by HPLC on a glycopeptide-type column chiral stationary phase . Biomed. Chromatogr. , 15 : 217 – 222 .
   PubMedGoogle Scholar
• Riegel , M. and Ellis , P.P. 1994. High-performance liquid chromatographic assay for anti-inflammatory agents diclofenac and flurbiprofen in ocular fluids. J. Chromatogr. B: Biomed. Sci. Appl. , 654 (1): 140–145.
   Google Scholar
• Sajeev , C. , Jadhav , P.R. , Ravishankar , D. , and Saha R.N. 2002 . Determination of flurbiprofen in pharmaceutical dosage form by UV spectrophotometry and LC . Analytica Chimica Acta , 463 ( 2 ): 207 – 217 .
   Web of Science ®Google Scholar
• Shah , V.P. , Midha , K.K. , Dighe , S. , McGilveray , I.J. , Skelly , J.P. , Yacobi , A. , Layoff , T. , Vishwanathan , C.T. , Cork , C.E. , McDowall , R.D. , Pitman , K.A. , and Spector , S. 1992 . Analytical methods validation: Bioavailability, bioequivalence and pharmacokinetic studies . Pharm. Res. , 9 : 588 – 592 .
   Web of Science ®Google Scholar
• Snider , B.G. , Beaubien , L.J. , Sears , D.J. , and Rahn , P.D. 1981 . Determination of flurbiprofen and ibuprofen in dog serum with automated sample preparation . J. Pharm. Sci. , 70 ( 12 ): 1347 – 1349 .
   PubMed Web of Science ®Google Scholar
• Soulier , S.M. , Page , J.C. , Larsen , L.C. , and Grose , B.C. 1997 . The efficacy of ANSAID (flurbiprofen) as an analgesic in foot surgery . J. Foot Ankle Surg. , 36 ( 6 ): 414 – 417 .
   PubMedGoogle Scholar
• Sud , R.N. , Greval , R.S. , and Bajwa , R.S. 1995 . Topical flurbiprofen therapy in vernal keratoconjunctivitis . Indian J. Med. Sci. , 49 ( 9 ): 205 – 209 .
   PubMedGoogle Scholar
• Tang-Liu , D.D-S. , Liu , S.S. , and Weinkam , R.J. 1984 . Ocular and systemic bioavailability of ophthalmic flurbiprofen . J. Pharmacokinet. Biopharm. , 12 : 611 – 626 .
   PubMedGoogle Scholar
• Teng , X.W. , Wang , S.W.J. , and Davies , N.M. 2003 . Stereospecific high-performance liquid chromatographic analysis of flurbiprofen: Application to pharmacokinetic studies . J. Pharm. Biomed. Anal. , 33 ( 1 ): 95 – 100 .
   PubMed Web of Science ®Google Scholar
• United States Pharmacoepia (USP), XXIV . 2000 . Monograph on Flurbirpofen, , 23rd ed . Rockville , MD : United States Pharmacoepial Convention , pp. 748 – 750 .
   Google Scholar
• United States Pharmacoepia (USP), XXVI . 2003 . Validation of Compendial Methods, , 26th ed. Rockville , MD : United States Pharmacoepial Convention , pp. 2439 – 2442 .
   Google Scholar
• Vajpayee , R.B. , Dhakal , B.P. , Gupta , S.K. , Sachdev , M.S. , Satpathy , G. , Honavar , S.G. , and Panda , A. 1996 . Evaluation of topical 0.03% flurbiprofen drops in the treatment of herpetic stromal keratitis . Aust. N. Z. J. Ophthalmol. , 24 ( 2 ): 131 – 135 .
   PubMedGoogle Scholar