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BIOANALYTICAL

Simultaneous Determination of Hydrochlorothiazide and Valsartan in Human Plasma by Liquid Chromatography/Tandem Mass Spectrometry

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Pages 1348-1365 | Received 01 Mar 2008, Accepted 18 Mar 2008, Published online: 10 Jul 2008

REFERENCES

  • Carlucci , G. , Di Carlo , V. , and Mazzeo , P. 2000 . Simultaneous determination of valsartan and hydrochlorothiazide in tablets by high-performance liquid chromatography . Anal. Lett. , 33 ( 12 ): 2491 – 2500 .
  • Crespo , M.J. and De Mello , W.C. 2001 . Chronic administration of losartan plus hydrochlorothiazide improves vascular status in young cardiomyopathic hamsters . Eur. J. Pharmacol. , 420 ( 2–3 ): 133 – 141 .
  • Dinc , E. , Uslu , B. , and Ozkan , S.A. 2004 . Spectral resolution of a binary mixture containing valsartan and hydrochlorothiazide in tablets by ratio spectra derivative and inverse least square techniques . Anal. Lett. , 37 ( 4 ): 679 – 693 .
  • Erk , N. 2002 . Spectrophotometric analysis of valsartan and hydrochlorothiazide . Anal. Lett. , 35 ( 2 ): 283 – 302 .
  • Huang , T.M. , He , Z. , Yang , B. , Shao , L.P. , Zheng , X.W. , and Duan , G.L. 2006 . Simultaneous determination of captopril and hydrochlorothiazide in human plasma by reverse-phase HPLC from linear gradient elution . J. Pharm. Biomed. Anal. , 41 ( 2 ): 644 – 648 .
  • Iriarte , G. , Ferreiros , N. , Ibarrondo , I. , Alonso , R.M. , Maguregi , M.I. , Gonzalez , L. , and Jimenez , R.M. 2006 . Optimization via experimental design of an SPE-HPLC-UV-fluorescence method for the determination of valsartan and its metabolite in human plasma samples . J. Sep. Sci. , 29 ( 15 ): 2265 – 2283 .
  • Kocyigit-Kaymakcoglu , B. , Unsalan , S. , and Rollas , S. 2006 . Determination and validation of ketoprofen, pantoprazole and valsartan together in human plasma by high performance liquid chromatography . Pharmazie , 61 ( 7 ): 586 – 589 .
  • Li , H. , Wang , Y.W. , Jiang , Y. , Tang , Y.B. , Wang , J. , Zhao , L.M. , and Gu , J.K. 2007 . A liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of valsartan and hydrochlorothiazide in human plasma . J. Chromatogr. B , 852 ( 1–2 ): 436 – 442 .
  • Macek , J. , Klima , J. , and Ptacek , P. 2006. Rapid determination of valsartan in human plasma by protein precipitation and high-performance liquid chromatography. J. Chromatogr. B , 832 (1): 169–172.
  • Matuszewski , B.K. , Constanzer , M.L. , and Chavez-Eng , C.M. 2003 . Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS . Anal. Chem. , 75 ( 13 ): 3019 – 3030 .
  • Miller , R.B. and Amestoy , C. 1992 . A liquid-chromatographic method for the determination of hydrochlorothiazide in human plasma . J. Pharm. Biomed. Anal. , 10 ( 7 ): 541 – 545 .
  • Mistry , N.B. , Westheim , A.S. , and Kjeldsen , S.E. 2006 . The angiotensin receptor antagonist valsartan: A review of the literature with a focus on clinical trials . Expert Opin. Pharmacother. , 7 ( 5 ): 575 – 581 .
  • Niopas , I. and Daftsios , A.C. 2002 . A validated HPLC method for the determination of hydrochlorothiazide in human plasma and its application in pharmacokinetic studies . J. Liq. Chromatogr. Relat. Technol. , 25 ( 3 ): 487 – 494 .
  • Pool , J.L. , Glazer , R. , Weinberger , M. , Alvarado , R. , Huang , J. , and Graff , A. 2007 . Comparison of valsartan/hydrochlorothiazide combination therapy at doses up to 320/25 mg versus monotherapy: A double-blind, placebo-controlled study followed by long-term combination therapy in hypertensive adults . Clin. Ther. , 29 ( 1 ): 61 – 73 .
  • Ramakrishna , N.V.S. , Vishwottam , K.N. , Manoj , S. , Koteshwara , M. , Wishu , S. , and Varma , D.P. 2005 . Sensitive liquid chromatography-tandem mass spectrometry method for quantification of hydrochlorothiazide in human plasma . Biomed. Chromatogr. , 19 ( 10 ): 751 – 760 .
  • Satana , E. , Altinay , S. , Goger , N.G. , Ozkan , S.A. , and Senturk , Z. 2001 . Simultaneous determination of valsartan and hydrochlorothiazide in tablets by first-derivative ultraviolet spectrophotometry and LC . J. Pharm. Biomed. Anal. , 25 ( 5–6 ): 1009 – 1013 .
  • Tatar , S. and Saglik , S. 2002 . Comparison of UV- and second derivative-spectrophotometric and LC methods for the determination of valsartan in pharmaceutical formulation . J. Pharm. Biomed. Anal. , 30 ( 2 ): 371 – 375 .
  • U.S. Department of Health and Human Services, Food and Drug Administration . 2001 , May . Guidance for Industry—Bioanalytical Method Validation .
  • Wagstaff , A.J. 2006 . Valsartan/hydrochlorothiazide—A review of its use in the management of hypertension . Drugs , 66 ( 14 ): 1881 – 1901 .
  • Wellington , K. and Faulds , D.M. 2002 . Valsartan/hydrochlorothiazide—A review of its pharmacology, therapeutic efficacy and place in the management of hypertension . Drugs , 62 ( 13 ): 1983 – 2005 .
  • Yang , H.Y. , Kao , P.F. , Chen , T.H. , Tomlinson , B. , Ko , W.C. , and Chan , P. 2007 . Effects of the angiotensin II type 1 receptor antagonist valsartan on the expression of superoxide dismutase in hypertensive patients . J. Clin. Pharmacol. , 47 ( 3 ): 397 – 403 .
  • Zendelovska , D. , Stafilov , T. , and Milosevski , P. 2004 . Development of solid-phase extraction method and its application for determination of hydrochlorothiazide in human plasma using HPLC . Biomed. Chromatogr. , 18 ( 2 ): 71 – 76 .

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