Determination of Belotecan in the Plasma, Bile, and Urine of Rats by High-Performance Liquid Chromatography with Fluorescence Detection and Its Application to a Pharmacokinetic Study

REFERENCES

• Beijnen , J.H. , Rosing , H. , ten Bokkel Huinink , W.W. , and Pinedo , H.M. 1993 . High-performance liquid chromatographic analysis of the antitumour drug camptothecin and its lactone ring-opened form in rat plasma . J. Chromatogr. , 617 : 111 – 117 .
   PubMedGoogle Scholar
• Beijnen , J.H. , Smith , B.R. , Keijer , W.J. , van Gijn , R. , ten Bokkel Huinink , W.W. , Vlasveld , L.T. , Rodenhuis , S. , and Underberg , W.J. 1990 . High-performance liquid chromatographic analysis of the new antitumour drug SK&F 104864-A (NSC 609699) in plasma . J. Pharm. Biomed. Anal. , 8 : 789 – 794 .
   PubMed Web of Science ®Google Scholar
• Cho , J.Y. , Seo , H.B. , Yu , K.S. , Bae , K.S. , Yi , S.Y. , Jang , I.J. , and Shin , S.G. 2003 . Simple and sensitive determination of the new antitumor drug CKD-602 in human plasma by liquid chromatography . J. Chromatogr. B , 784 : 25 – 31 .
   PubMed Web of Science ®Google Scholar
• Fassberg , J. and Stella , V.J. 1992 . A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues . J. Pharm. Sci. , 81 : 676 – 684 .
   PubMed Web of Science ®Google Scholar
• Jew , S.S. , Kim , M.G. , Kim , H.J. , Rho , E.Y. , Park , H.G. , Kim , J.K. , Han , H.J. , and Lee , H. 1998 . Synthesis and in vitro cytotoxicity of C(20)(RS)-camptothecin analogues modified at both B (or A) and E ring . Bioorg. Med. Chem. Lett. , 8 : 1797 – 1800 .
   PubMed Web of Science ®Google Scholar
• Lee , D. , Kim , S.W. , Suh , C. , Lee , J.S. , Lee , J. , Lee , S.J. , Ryoo , B. , Park , K. , Kim , J. , Heo , D. , and Kim , N. 2007 . Belotecan, new camptothecin analogue, is active in patients with small-cell lung cancer: Results of a multicenter early phase II study . Ann. Oncol. , 19 : 123 – 127 .
   PubMedGoogle Scholar
• Lee , J.H. , Lee , J.H. , Kim , J.K. , Shin , H.J. , Lee , H.K. , Lee , S.J. , and Hong , C.I. 1998 . Pharmacokinetic study of CKD-602, a new camptothecin derivative: Distribution, metabolism, and excretion . Yakhak. Hoeji , 42 : 437 – 446 .
   Google Scholar
• Lee , J.H. , Lee , J.M. , Kim , J.K. , Ahn , S.K. , Lee , S.J. , Kim , M.Y. , Jew , S.S. , Park , J.G. , and Hong , C.I. 1998. Antitumor activity of 7-[2-(N-isopropylamino)ethyl]-(20S)-camptothecin, CKD602, as a potent DNA topoisomerase I inhibitor. Arch. Pharm. Res. , 21: 581–590.
   PubMed Web of Science ®Google Scholar
• Lee , J.H. , Lee , J.M. , Lim , K.H. , Kim , J.K. , Ahn , S.K. , Bang , Y.J. , and Hong , C.I. 2000 . Preclinical and phase I clinical studies with CKD-602, a novel camptothecin derivative . Ann. N. Y. Acad. Sci. , 922 : 324 – 325 .
   PubMed Web of Science ®Google Scholar
• Lee , J.H. , Sohn , Y.S. , Kim , J.K. , Shin , H.J. , Lee , H.K. , Lee , S.J. , and Hong , C.I. 1998 . Pharmacokinetic study of CKD-602, a new camptothecin derivative: Absorption . Yakhak. Hoeji , 42 : 431 – 436 .
   Google Scholar
• Rivory , L.P. and Robert , J. 1994 . Reversed-phase high-performance liquid chromatographic method for the simultaneous quantitation of the carboxylate and lactone forms of the camptothecin derivative irinotecan, CPT-11, and its metabolite SN-38 in plasma . J. Chromatogr. B , 661 : 133 – 141 .
   PubMedGoogle Scholar
• Rosing , H. , Doyle , E. , and Beijnen , J.H. 1996 . The impact of column temperature in the high performance liquid chromatographic analysis of topotecan in rat and dog plasma . J. Pharm. Biomed. Anal. , 15 : 279 – 286 .
   PubMed Web of Science ®Google Scholar
• Rosing , H. , Doyle , E. , Davies , B.E. , and Beijnen , J.H. 1995 . High-performance liquid chromatographic determination of the novel antitumour drug topotecan and topotecan as the total of the lactone plus carboxylate forms, in human plasma . J. Chromatogr. B , 668 : 107 – 115 .
   PubMed Web of Science ®Google Scholar
• Sha , X. and Fang , X. 2004 . Transport characteristics of 9-nitrocamptothecin in the human intestinal cell line Caco-2 and everted gut sacs . Int. J. Pharm. , 272 : 161 – 171 .
   PubMed Web of Science ®Google Scholar
• Slichenmyer , W.J. , Rowinsky , E.K. , Donehower , R.C. , and Kaufmann , S.H. 1993 . The current status of camptothecin analogues as antitumor agents . J. Natl. Cancer Inst. , 85 : 271 – 291 .
   PubMed Web of Science ®Google Scholar
• Sumiyoshi , H. , Fujiwara , Y. , Ohune , T. , Yamaoka , N. , Tamura , K. , and Yamakido , M. 1995 . High-performance liquid chromatographic determination of irinotecan (CPT-11) and its active metabolite (SN-38) in human plasma . J. Chromatogr. B , 670 : 309 – 316 .
   PubMedGoogle Scholar
• Takimoto , C.H. , Klecker , R.W. , Dahut , W.L. , Yee , L.K. , Strong , J.M. , Allegra , C.J. , and Grem , J.L. 1994 . Analysis of the active lactone form of 9-aminocamptothecin in plasma using solid-phase extraction and high-performance liquid chromatography . J. Chromatogr. B , 655 : 97 – 104 .
   PubMedGoogle Scholar
• Vali , A.M. , Shafaghi , B. , and Dadashzadeh , S. 2005 . Simple and sensitive high performance liquid chromatographic method for the simultaneous quantitation of the lactone and carboxylate forms of topotecan in human plasma . J. Chromatogr. B , 818 : 205 – 212 .
   PubMed Web of Science ®Google Scholar
• van Warmerdam , L.J. , Verweij , J. , Schellens , J.H. , Rosing , H. , Davies , B.E. , de Boer-Dennert , M. , Maes , R.A. , and Beijnen , J.H. 1995 . Pharmacokinetics and pharmacodynamics of topotecan administered daily for 5 days every 3 weeks . Cancer Chemother. Pharmacol. , 35 : 237 – 245 .
   PubMed Web of Science ®Google Scholar