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MASS SPECTROMETRY

Rapid Detection of the Residual Kryptofix 2.2.2 Levels in [18F]-Labeled Radiopharmaceuticals by Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry

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Pages 1197-1205 | Received 04 Mar 2010, Accepted 26 May 2010, Published online: 14 Jun 2011

REFERENCES

  • Alexoff , D. L. , J. S. Fowler , and S. J. Gatley . 1991 . Removal of the 2.2.2 cryptand (Kryptofix 2.2.2TM) from 18FDG by cation exchange . Appl. Radiat. Isot. 42 : 1189 – 1193 .
  • Bartolucci , G. , G. Pieraccini , F. Villanelli , G. Moneti , and A. Triolo . 2000 . Liquid chromatography tandem mass spectrometric quantitation of sulfamethazine and its metabolites: Direct analysis of swine urine by triple quadrupole and by ion trap mass spectrometry . Rapid Commun. Mass Spectrom. 14 : 967 – 973 .
  • Chaly , T. , and J. R. Dahl . 1989. Thin layer chromatographic detection of Kryptofix 2.2.2 in the routine synthesis of [18F] 2-Fluoro-2-deoxy-D-glucose. Nucl. Med. Biol. 16: 385–387.
  • Ferrieri , R. A. , D. J. Schlyer , D. L. Alexoff , J. S. Fowler , and A. P. Wolf . 1993 . Direct analysis of Kryptofix, 2.2.2 in 18FDG by gas chromatography using a nitrogen-selective detector . Nucl. Med. Biol. 20 : 367 – 369 .
  • Franck , D. , H. Nann , P. Davi , P. A. Schubiger , and S. M. Ametamey . 2009 . Faster analysis of radiopharmaceuticals using ultra performance liquid chromatography (UPLC) in combination with low volume radio flow cell . Appl. Radiat. Isot. 67 : 1068 – 1070 .
  • Kaufmann , A. , and P. Butcher . 2005 . Quantitative liquid chromatography/tandem mass spectrometry determination of chloramphenicol residues in food using sub-2 µm particulate high-performance liquid chromatography columns for sensitivity and speed . Rapid Commun. Mass Spectrom. 19 : 3694 – 3700 .
  • Kruse , M. A. , S. E. Rees , and G. L. Watkins . 2000 . Quality control of kryptofix or tetrabutylammonium ion in FDG samples by quantitative HPLC analysis . J. Nuclear Medicine 41 : 148 .
  • Lewis, Sr. , R. J. , and R. L. Tatken , Eds. 1979 . Registry of Toxic Effects of Chemical Substances . Cincinnati , OH : US Department of Health and Human Services, Center for Disease Control.
  • Lim , C. K. , and T. J. Peters . 1984 . Ammonium acetate: A general purpose buffer for clinical applications of high-performance liquid chromatography . J. Chromatogr. 316 : 397 – 406 .
  • Ma , Y. , B. X. Huang , M. A. Channing , and W. C. Eckelman . 2002 . Quantification of Kryptofix 2.2.2 in 2-[18F]FDG and other radio pharmaceuticals by LC/MS/MS . Nucl. Med. Biol. 29 : 125 – 129 .
  • March , R. E. , M. Splendore , E. J. Reiner , R. S. Mercer , J. B. Plomley , D. S. Waddell , and K. A. Macpherson . 2000 . A comparison of three mass spectrometric methods for the determination of dioxins/furans . Int. J. Mass Spectrom. 194 : 235 – 246 .
  • Mock , B. H. , W. Winkle , and M. T. Vavrek . 1997 . A color spot test for the detection of Kryptofix 2.2.2 in [18F]FDG preparations . Nucl. Med. Biol. 24 : 193 – 195 .
  • Moerlin , S. M. , J. W. Brodack , B. A. Siegel , and M. J. Welch . 1989 . Elimination of contaminant Kryptofix 2.2.2 in the routine production of 2-[18F]fluoro-2-deoxy-D-glucose . Appl. Radiat. Isot. 40 : 741 – 743 .
  • Nakao , R. , T. Ito , K. Hayashi , T. Fukumura , M. Yamaguchi , and K. Suzuki . 2009 . 1-Minute quality control tests for positron emission tomography radiopharmaceuticals . J. Pharm. Biomed. Anal. 50 : 245 – 251 .
  • Nakao , R. , T. Ito , M. Yamaguchi , and K. Suzuki . 2008 . Simultaneous analysis of FDG, ClDG and Kryptofix 2.2.2 in [18F]FDG preparation by high-performance liquid chromatography with UV detection . Nucl. Med. Biol. 35 : 239 – 244 .
  • Scott , P. J. H. , and M. R. Kilbourn . 2007 . Determination of residual Kryptofix 2.2.2 Levels in [18F]-labeled radiopharmaceuticals for human use . Appl. Radiat. Isot. 65 : 1359 – 1362 .
  • Soler , C. , J. Mañes , and Y. Picó . 2005 . Comparison of liquid chromatography using triple quadrupole and quadrupole ion trap mass analyzers to determine pesticide residues in oranges . J. Chromatogr. A. 1067 : 115 – 125 .
  • United States Pharmacopeia (USP). USP-29, NF-24 , 2006 . Fludeoxyglucose F-18 Injection. USP-29, NF-24, Official Monographs . pp. 933 – 944 .
  • Wang , C. , G. Fan , M. Lin , Y. Chen , W. Q. Zhao , and Y. T. Wu . 2007 . Development of a liquid chromatography/tandem mass spectrometry assay for the determination of bestatin in rat plasma and its application to a pharmacokinetic study . J. Chromatogr. B. 850 : 101 – 108 .

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