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BIOANALYTICAL

Impedance Based Nanotoxicity Assessment of Graphene Nanomaterials at the Cellular and Tissue Level

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Pages 272-282 | Received 31 Dec 2010, Accepted 08 Mar 2011, Published online: 03 Feb 2012

REFERENCES

  • Alwarappan , S. , A. Erdem , C. Liu , and C.-Z. Li . 2009 . Probing the electrochemical properties of graphene nanosheets for biosensing applications . J. Phys. Chem. C 113 ( 20 ): 8853 – 8857 .
  • Biswas , S. , and L. T. Drzal . 2008 . A novel approach to create a highly ordered monolayer film of graphene nanosheets at the liquid-liquid interface . Nano Lett. 9 ( 1 ): 167 – 172 .
  • Brayner , R. 2008. The toxicological impact of nanoparticles. NanoToday 3: 48–55.
  • Chang , Y. , S.-T. Yang , J.-H. Liu , E. Dong , Y. Wang , A. Cao , Y. Liu , and H. Wang . 2010 . In vitro toxicity evaluation of graphene oxide on A549 cells . Toxicol. Lett. 200 ( 3 ): 201 – 210 .
  • Chen , H. , M. B. Müller , K. J. Gilmore , G. G. Wallace , and D. Li . 2008 . Mechanically strong, electrically conductive, and biocompatible graphene paper . Adv. Mater. 20 ( 18 ): 3557 – 3561 .
  • Fan , H. , L. Wang , K. Zhao , N. Li , Z. Shi , Z. Ge , and Z. Jin . 2010 . Fabrication, mechanical properties, and biocompatibility of graphene-reinforced chitosan composites . Biomacromolecules 11 ( 9 ): 2345 – 2351 .
  • Fenoglio , I. , G. Greco , M. Tomatis , J. Muller , E. Raymundo-Pinero , F. O. Beguin , A. Fonseca , J. B. Nagy , D. Lison , and B. Fubini . 2008 . Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: Physicochemical aspects . Chem. Res. Toxicol. 21 ( 9 ): 1690 – 1697 .
  • Hondroulis , E. , C. Liu , and C Z. Li . 2010 . Whole cell based electrical impedance sensing approach for a rapid nanotoxicity assay . Nanotechnology 21 ( 31 ): 315103 .
  • Hummers , W. S. , and R. E. Offeman . 1958 . Preparation of graphitic oxide . J. Am. Chem. Soc. 80 ( 6 ): 1339 – 1339 .
  • Hurt , R. H. , M. Monthioux , and A. Kane . 2006 . Toxicology of carbon nanomaterials: Status, trends, and perspectives on the special issue . Carbon 44 ( 6 ): 1028 – 1033 .
  • Li , C.-Z. , and S. Alwarappan . 2010 . Simultaneous detection of dopamine, ascorbic acid and uric acid at electrochemically activated carbon nanotube biosensors . Nanomedicine NBM 6 : 52 – 57 .
  • Li , C.-Z. , K. Nishiyama , and I. Taniguchi . 2000 . Electrochemical and spectroelectrochemical studies on cobalt myoglobin . Electrochim. Acta. 45 : 2883 – 2888 .
  • Li , Y. , Y. Liu , Y. Fu , T. Wei , L. L. Guyader , G. Gao , R. S. Liu , Y. Z. Chang , and C. Chen . 2012 . The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signalling pathways. Biomaterials 33 ( 2 ): 402 – 411 .
  • Liu , C. , S. Alwarappan , Z. Chen , X. Kong , and C.-Z. Li . 2009 . Membraneless enzymatic biofuel cells based on graphene nanosheets . Biosensors Bioelectron. 25 ( 7 ): 1829 – 1833 .
  • Liu , Y. , D. Yu , C. Zeng , Z. Miao , and L. Dai . 2010 . Biocompatible graphene oxide-based glucose biosensors . Langmuir 26 ( 9 ): 6158 – 6160 .
  • Liu , Z. , K. Chen , C. Davis , S. Sherlock , Q. Cao , X. Chen , and H. Dai . 2008 . Drug delivery with carbon nanotubes for in vivo cancer treatment . Cancer Res. 68 ( 16 ): 6652 – 6660 .
  • Poland , C. A. , R. Duffin , I. Kinloch , A. Maynard , W. A. H. Wallace , A. Seaton , V. Stone , S. Brown , W. MacNee , and K. Donaldson . 2008 . Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study . Nat. Nano 3 ( 7 ): 423 – 428 .
  • Prabhulkar , S. , and C.-Z. Li . 2010 . Assessment of oxidative DNA damage and repair at single cellular level via real-time monitoring of 8-OHdG biomarker . Biosensors Bioelectron. 26 ( 4 ): 1743 – 1749 .
  • Pulskamp , K. , S. Diabaté , and H. F. Krug . 2007 . Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants . Toxicol. Lett. 168 ( 1 ): 58 – 74 .
  • Pulskamp , K. , J. M. Wörle-Knirsch , F. Hennrich , K. Kern , and H. F. Krug . 2007 . Human lung epithelial cells show biphasic oxidative burst after single-walled carbon nanotube contact . Carbon 45 ( 11 ): 2241 – 2249 .
  • Pumera , M. 2007 . Carbon nanotubes contain residual metal catalyst nanoparticles even after washing with nitric acid at elevated temperature because these metal nanoparticles are sheathed by several graphene sheets . Langmuir 23 ( 11 ): 6453 – 6458 .
  • Pumera , M. 2010 . Nanotoxicology: The molecular science point of view. Chemistry – An Asian journal, n/a. doi: 10.1002/asia.201000398
  • Sayes , C. M. , A. M. Gobin , K. D. Ausman , J. Mendez , J. L. West , and V. L. Colvin . 2005. Nano-C60 cytotoxicity is due to lipid peroxidation. Biomaterials 26(36): 7587–7595.
  • Sayes , C. M. , A. A. Marchione , K. L. Reed, and D. B. Warheit . 2007 . Comparative pulmonary toxicity assessments of c60 water suspensions in rats: Few differences in fullerene toxicity in vivo in contrast to in vitro profiles . Nano Lett. 7 ( 8 ): 2399 – 2406 .
  • Shao , Y. , J. Wang , H. Wu , J. Liu , I. A. Aksay , and Y. Lin . 2009 . Graphene based electrochemical sensors and biosensors: A review . Electroanalysis 22 ( 10 ): 1027 – 1036 .
  • Sun , X. , Z. Liu , K. Welsher , J. Robinson , A. Goodwin , S. Zaric , and H. Dai . 2008 . Nano-graphene oxide for cellular imaging and drug delivery . Nano Res. 1 ( 3 ): 203 – 212 .
  • Tian , F. , D. Cui , H. Schwarz , G. G. Esorada , and H. Kobayashi . 2006 . Cytotoxicity of single-wall carbon nanotubes on human fibroblasts . Toxicol. In Vitro 20 : 1202 – 1212 .
  • Warheit , D. B. , B. R. Laurence , K. L. Reed , D. H. Roach , G. A. M. Reynolds , and T. R. Webb . 2004 . Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats . Toxicol. Sci. 77 ( 1 ): 117 – 125 .
  • Zhang , Y. , S. F. Ali , E. Dervishi , Y. Xu , Z. Li , D. Casciano , and A. S. Biris . 2010 . Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma-derived PC12 cells . ACS Nano 4 ( 6 ): 3181 – 3186 .
  • Zhang , Z. , A. McGoron , E. Crumpler , and C.-Z. Li . 2010 . Co-culture based blood-brain barrier in vitro model, a tissue engineering approach using immortalized cell lines for drug transport study . Appl. Biochem. Biotechnol. 163 ( 2 ): 278 – 295 .

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