Impurity Profiling of Dirithromycin by Liquid Chromatography Coupled to Electrospray Ionization Mass Spectrometry

REFERENCES

• Bryskier , A. 1998 . Novelties in the field of anti-infectives in 1997 . CID 27 : 856 – 883 .
   Web of Science ®Google Scholar
• Counter , F. T. , P. W. Ensminger , D. A. Preston , C.-Y. E. Wu , J. M. Greene , A. M. Felty-Duckworth , J. W. Paschal , and H. A. Kirst . 1991 . Synthesis and antimicrobial evaluation of dirithromycin (AS-E 136; LY237216), a new macrolide antibiotic derived from erythromycin . Antimicrob Agents Chemother. 35 : 1116 – 1126 .
   PubMed Web of Science ®Google Scholar
• Diana , J. , V. Manyanga , J. Hoogmartens , and E. Adams . 2006 . Development and validation of an improved liquid chromatographic method for the analysis of dirithromycin . Talanta 70 : 1064 – 1072 .
   Web of Science ®Google Scholar
• Diana , J. , C. Govaerts , J. Hoogmartens , A. Van Schepdael , and E. Adams . 2006 . Characterization of impurities in dirithromycin by liquid chromatography/ion trap mass spectrometry . J. Chromatogr. A. 1125 ( 1 ): 52 – 66 .
   Web of Science ®Google Scholar
• Duran , D. , V. Aviyente , and C. Baysal . 2004 . A computational approach to the synthesis of dirithromycin . J. Mol. Model. 10 : 94 – 101 .
   Web of Science ®Google Scholar
• European Pharmacopoeia. 6th ed. 2008 . Strasbourg , France : EDQM Publications , 3447 – 3449 .
   Google Scholar
• Firl , J. , A. Prox , P. Luger , R. Maier , E. Woitun , and K. Daneck . 1990 . Epimerization of erythromycin derivatives . J. Antibiot. 43 : 1271 – 1277 .
   Web of Science ®Google Scholar
• Geerdes-Fenge , H. F. , B. Goetschi , M. Rau , K. Borner , P. Koeppe , K. Wettich , and H. Lode . 1997 . Comparative pharmacokinetics of dirithromycin and erythromycin in normal volunteers with special regard to accumulation in polymorphonuclear leukocytes and in saliva . Eur. J. Clin. Pharmacol. 53 : 127 – 133 .
   Web of Science ®Google Scholar
• Govaerts , C. , H. K. Chepkwony , A. Van Schepdael , E. Roets , and J. Hoogmartens . 2000 . Investigation of unknown related substances in commercial erythromycin samples with liquid chromatography/mass spectrometry . Rapid Commun. Mass Spectrom. 14 : 878 – 884 .
   Web of Science ®Google Scholar
• Kanfer , I. , M. F. Skinner , and R. B. Walker . 1998 . Analysis of macrolides . J. Chromatogr. A. 812 : 255 – 286 .
   PubMed Web of Science ®Google Scholar
• Kirst , H. A. , L. C. Creemer , J. W. Paschal , D. A. Preston , W. E. Alborn , F. T. Counter , J. G. Amos , R. L. Clemens , K. A. Sullivan , and J. M. Greene . 1995. Antimicrobial characterization and interrelationships of dirithromycin and epidirithromycin. Antimicrob. Agents Chemother. 39: 1436–1441.
   Web of Science ®Google Scholar
• Kujundzic , N. , D. Pavlovis , G. Kobrehel , G. Lazarevski , and Z. Kelneric . 1998 . 9-N-ethenyl derivatives of 9(S)-erythromycylamine . US Patent. 5 : 854 – 219 .
   Google Scholar
• Luger , P. , and R. Maier . 1979 . Molecular structure of 9-deoxy-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethylidene)oxy)-(9S)-erythromycin, a new erythromycin derivative . J. Crystallogr. Mol. Struct. 9 : 329 – 338 .
   Web of Science ®Google Scholar
• Pendela , M. , J. Hoogmartens , A. Van Schepdael , and E. Adams . 2009 . LC-MS of streptomycin following desalting of a nonvolatile mobile phase and pH gradient . J. Sep. Sci. 32 : 3418 – 3424 .
   Web of Science ®Google Scholar