Dynamic Metabolic Profiling of Urine From Type 2 Diabetic KK-Ay Mice Treated with Repaglinide by GC-MS

REFERENCES

• Akanuma , Y. , M. Morita , N. Fukuzawa , T. Yamanouchi , and H. Akanuma . 1988 . Urinary excretion of 1,5-anhydro-D-glucitol accompanying glucose excretion in diabetic patients . Diabetologia 31 : 831 – 835 .
   PubMed Web of Science ®Google Scholar
• Brownlee , M. 2005 . The pathobiology of diabetic complications: A unifying mechanism . Diabetes 54 : 1615 – 1625 .
   PubMed Web of Science ®Google Scholar
• Crane , R. K. 1960 . Intestinal absorption of sugars . Physiol. Rev. 40 : 789 – 825 .
   PubMed Web of Science ®Google Scholar
• Crane , R. K. , and P. Mandelstam . 1960 . The active transport of sugars by various preparations of hamster intestine . Biochim. Biophys. Acta 45 : 460 – 476 .
   PubMed Web of Science ®Google Scholar
• Dai , Y. , Z. Y. Li , L. M. Xue , C. Y. Dou , Y. Z. Zhou , L. Z. Zhang , and X. M. Qin . 2010 . Metabolomics study on the anti-depression effect of xiaoyaosan on rat model of chronic unpredictable mild stress . J. Ethnopharmacol. 128 : 482 – 489 .
   PubMed Web of Science ®Google Scholar
• DeFronzo , R. A. , R. C. Bonadonn , and E. Ferrannini . 1992. Pathogenesis of NIDDM: a balanced overview. Diabetes Care 15: 318–368.
   PubMed Web of Science ®Google Scholar
• Dunn , W. B. , R. Goodacre , L. Neyses , and M. Mamas . 2011 . Integration of metabolomics in heart disease and diabetes research: current achievements and future outlook . Bioanalysis 3 ( 19 ): 2205 – 2222 .
   PubMed Web of Science ®Google Scholar
• Fonseca , V. A. , D. E. Kelley , W. Cefalu , M. A. Baron , D. Purkayastha , J. E. Nestler , S. Hsia , and J. E. Gerich . 2004 . Hypoglycemic potential of nateglinide versus glyburide in patients with type 2 diabetes mellitus . Metabolism 53 ( 10 ): 1331 – 1335 .
   Web of Science ®Google Scholar
• Fujita , T. , Y. Sugiyama , S. Taketomi , T. Sohda , Y. Kawamatsu , H. Iwatsuka , and Z. Suzuoki . 1983 . Reduction of insulin resistance in obese and/or diabetic animals by 5-[4-(1-methylcyclohexylmethoxy) benzy1]-thiazolidine-2,4-dione(ADD-3878, U-63, 287, ciglitazone), a new antidiabetic agent . Diabetes 32 : 804 – 810 .
   PubMed Web of Science ®Google Scholar
• Griffin , J. L. , and A. W. Nicholls . 2006 . Metabolomics as a functional genomic tool for understanding lipid dysfunction in diabetes, obesity and related disorders . Pharmacogenomics 7 ( 10 ): 95 – 107 .
   Google Scholar
• Hirshberg , B , M. C. Skarulis , F. Pucino , G. Csako , R. Brennan , and P. Gorden . 2001 . Repaglinide-induced factitious hypoglycemia . J. Clin. Endocrinal. Metab. 86 ( 2 ): 475 – 477 .
   Web of Science ®Google Scholar
• Huang , X. , Y. F. Gong , K. Yu , and Y. Y. Cheng . 2007 . Gas chromatography-mass spectrometry based on metabonomics study of carbon tetrachloride-induced acute liver injury in mice . Chin. J. Anal. Chem. 35 ( 12 ): 1736 – 1740 .
   Web of Science ®Google Scholar
• Jovanovic , L. , G. Dailey , W. C. Huang , P. Strange , and B. J. Goldstein . 2000 . Repaglinide in Type 2 diabetes: a 24-week, fixed-dose efficacy and safety study . J. Clin. Pharmacol. 40 : 49 – 57 .
   PubMed Web of Science ®Google Scholar
• Kawa , J. M. , R. Przybylski , and C. G. Taylor . 2003 . Urinary chiro-Inositol and myo-Inositol excretion is elevated in the diabetic db/db mouse and streptozotocin diabetic rat . Exp. Biol. Med. 228 : 907 – 914 .
   PubMed Web of Science ®Google Scholar
• Klonsky , J. , and M. M. Murr . 2009 . Metabolic surgery for type 2 diabetes mellitus . Insulin 4 ( 3 ): 136 – 143 .
   Google Scholar
• Landgraf , R. , M. Frank , C. Bauer , and M. L. Dieken . 2000 . Prandial glucose regulation with repaglinide: Its clinical and lifestyle impact in a large cohort of patients with type 2 diabetes . Int. J. Obes. 24 : 38 – 44 .
   Google Scholar
• Li , X. Y. , L. S. Ling , Z. K. He , G. W. Song , S. F. Lu , L. J. Yuan , and Y. E. Zeng . 2000 . Development of a chemiluminescence method for the simultaneous determination of pyruvic and tartaric acids in human serum based upon their reaction with cerium_IV/ in the presence of rutheniumtrispyridine . Microchem. J. 64 : 9 – 13 .
   Web of Science ®Google Scholar
• Malaisse , W. J. 1995 . Stimulation of insulin release by non-sulfonylurea hypoglycemic agents: the meglitinide family . Horm. Metab. Res. 27 : 263 – 266 .
   PubMed Web of Science ®Google Scholar
• Marinova , M. , G. Kyuchoukov , J. Albet , J. Molinier , and G. Malmary . 2004 . Separation of tartaric and lactic acids by means of solvent extraction . Sep. Purif. Technol. 37 : 199 – 207 .
   Web of Science ®Google Scholar
• Martin , A. , C. Ralnbal , V. Berger , S. Perier , and P. Louisot . 1998 . Availability of specific sugars for glycoconjugale biosynthesis: A need for further investigations in man . Biochimic 80 : 75 – 86 .
   PubMed Web of Science ®Google Scholar
• McKillop , A. M. , and P. R. Flatt . 2011 . Emerging applications of metabolomic and genomic profiling in diabetic clinical medicine . Diab. Care 34 ( 12 ): 2624 – 2630 .
   Web of Science ®Google Scholar
• Moses , R. 2000 . A review of clinical experience with the prandial glucose regulator, repaglinide, in the treatment of type 2 diabetes . Expert. Opin. Pharmacother. 1 : 1455 – 1467 .
   PubMedGoogle Scholar
• Moses , R. G. , R. Gomis , K. B. Frandsen , J.-L. Schlienger , and I. Dedov . 2001 . Flexible meal-related dosing with repaglinide facilitates glycaemic control in therapy-naive Type 2 diabetes . Diab. Care 24 : 11 – 15 .
   PubMed Web of Science ®Google Scholar
• Nicholson , J. K. , J. C. Lindon , and E. Holmes . 1999 . “Metabonomics”: understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis for biological NMR spectroscopic data . Xenobiotica 29 : 1181 – 1189 .
   PubMed Web of Science ®Google Scholar
• Polonsky , K. S. , B. D. Given , L. J. Hirsch , H. Tillil , E. T. Shapiro , C. Beebe , B. H. Frank , G. A. Galloway , and E. V. Cauter . 1988. Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. N. Engl. J. Med. 318: 1231–1239.
   PubMed Web of Science ®Google Scholar
• Tanabe , T. , S. Tajima , T. Suzuki , E. Okawa , R. Machida , S. Ichimura , and M. Yabuuchi . 1997 . Quantification of 1,5-anhydro-D-glucitol in urine by automated borate complex anion-exchange chromatography with an immobilized enzyme reactor . J. Chromatogr. B 692 : 23 – 30 .
   PubMed Web of Science ®Google Scholar
• Van der Kloet , F. M. , F. W. A. Tempels , N. Ismail , R. van der Heijden , P. T. Kasper , M. Rojas-Cherto , et al. 2012 . Discovery of early stage biomarkers for kidney disease using ms-based metabolomics (FinnDiane study) . Metabolomics 8 : 109 – 119 .
   Web of Science ®Google Scholar
• Van Gaal , L.F. , K. L. Van Acker , and I. H. De Leeuw . 2001 . Repaglinide improves blood glucose control in sulphonylurea-naive Type 2 diabetes . Diab. Res. Clin. Pract. 53 : 141 – 148 .
   PubMed Web of Science ®Google Scholar
• Wolffenbuttel , B. H. R. , L. Nijst , J. P. J. E. Sels , P. P. C. A. Menheere , P. G. Müller , and A. C. Nieuwenhuijzen Kruseman . 1993 . Effects of a new oral hypoglycaemic agent, repaglinide,on metabolic control in sulphonylurea-treated patients with NIDDM . Eur. J. Clin. Pharmacol. 45 : 113 – 116 .
   PubMed Web of Science ®Google Scholar
• Yamanouchi , T. , I. Akaoka , Y. Akanuma , H. Akanuma , and H. Miyashita . 1990 . Mechanism for acute reduction of 1,5-anhydroglucitol in rats treated with diabetogenic agents . Am. J. Physiol. 258 : E423 – E427 .
   Web of Science ®Google Scholar
• Yamanouchi , T. , N. Ogata , T. Yoshimura , T. Inoue , E. Ogata , T. Kawasaki , A. Kashiwabara , and H. Muraoka . 2000 . Transport of 1,5-anhydro-D-glucitol into insulinoma cells by a glucose-sensitive transport system . Biochim. Biophys. Acta 1474 : 291 – 298 .
   Web of Science ®Google Scholar