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Original Articles

The chemotherapy of rodent malaria, XXXVII

The in vivo action of two Mannich bases, WR 194,965 and WR 228,258 and an 8-aminoquinoline WR 225,448

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Pages 561-565 | Received 16 May 1983, Published online: 15 Nov 2016

REFERENCES

  • Boulard, Y., Ellis, E., Landau, I., Miltgen, F. & Peters, W. (1983). The chemotherapy of rodent malaria, XXXIV. Causal prophylaxis, part III: Ultrastructural changes induced in exo-erythrocytic schizonts of Plasmodium yoelii yoelii by primaquine. Annals of Tropical Medicine and Parasitology, 77, 555–568.
  • Davidson, D. E., Acer, A. L., Brown, J. L., Chapple, F. E., Whitmire, R. D. & Rossan, R. N. (1981). New tissue schizontocidal antimalarial drugs. Bulletin of the World Health Organization, 59, 463–479.
  • Peters, W., Portus, J. & Robinson, B. L. (1975a). The chemotherapy of rodent malaria, XXII. The value of drug-resistant strains of P. berghei in screening for blood schizontocidal activity. Annals of Tropical Medicine and Parasitology, 69, 155–171.
  • Peters, W., Davies, E. E. & Robinson, B. L. (1975b). The chemotherapy of rodent malaria, XXIII. Causal prophylaxis, part II: Practical experience with P. berghei nigeriensis in drug screening. Annals of Tropical Medicine and Parasitology, 69, 311–328.
  • Peters, W., Chance, M. L., Lissner, R., Momen, H. & Warhurst, D. C. (1977a). The chemotherapy of rodent malaria, XXX. The enigmas of the ‘NS lines’ of P. berghei. Annals of Tropical Medicine and Parasitology, 72, 23–36.
  • Peters, W., Portus, J. H. & Robinson, B. L. (1977b). The chemotherapy of rodent malaria, XXVIII. The development of resistance to mefloquine (WR 142,490). Annals of Tropical Medicine and Parasitology, 71, 419–427.
  • Peters, W., Ellis, D., Boulard, Y. & Landau, I. (1984a). The chemotherapy of rodent malaria, XXXVI. Causal prophylaxis, part IV: The activity of a new 8-aminoquinoline, WR 225,448 against exo-erythrocytic schizonts of P. yoelii yoelii. Annals of Tropical Medicine and Parasitology, 78, 467–478.
  • Peters, W., Irare, S. G., Ellis, D. S., Warhurst, D. C. & Robinson, B. L. (1984b). The chemotherapy of rodent malaria, XXXVIII. Studies on the activity of three new antimalarials (WR 194,965, WR 228,258, WR 225,448) against rodent and human malaria parasites (Plasmodium berghei and P. falciparum). Annals of Tropical Medicine and Parasitology, 78, 567–579.
  • Schmidt, L. H. & Crosby, R. (1978). Antimalarial activities of WR 194,965, an α-amino-o-cresol derivative. Antimicrobial Agents and Chemotherapy, 14, 672–679.
  • Schmidt, L. H., Vaughan, D., Mueller, D., Crosby, R. & Hamilton, R. (1977). Activities of various 4-aminoquinolines against infections with chloroquine-resistant strains of Plasmodium falciparum. Antimicrobial Agents and Chemotherapy, 11, 826–843.
  • Schofield, P., Howells, R. E. & Peters, W. (1981). A technique for the selection of long-acting antimalarial compounds using a rodent malaria model. Annals of Tropical Medicine and Parasitology, 75, 521–531.
  • Sweeney, T. R., Davidson, D. E., Nodiff, E. A., Saggiomo, A. J. & Lamontagne, M. P. (1983). Recent developments in potential 8- and 4-aminoquinoline antimalarial drugs. In Chemotherapy and Immunology in the Control of Malaria, Filariasis and Leishmaniasis, eds. Anand, N. & Sen, A. B., pp. 36–57. New Delhi: Tata McGraw-Hill.

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