Advanced search
Publication Cover
Annals of Tropical Medicine & Parasitology Volume 87, 1993 - Issue 1
Journal homepage
9
Views
33
CrossRef citations to date
0
Altmetric
Original Articles

The chemotherapy of rodent malaria. XLVIII. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 1: Studies leading to the development of novel cis-fused cyclopenteno derivatives

W. PetersCAB International Institute of Parasitology, 395a Hatfield Road, St. Albans, HertfordshireAL4 0XU, U.K.
,
B. L. RobinsonCAB International Institute of Parasitology, 395a Hatfield Road, St. Albans, HertfordshireAL4 0XU, U.K.
,
J. C. RossierDepartment of Organic Chemistry, University of Geneva, CH-1211, Geneva 4, Switzerland
&
C. W. JeffordDepartment of Organic Chemistry, University of Geneva, CH-1211, Geneva 4, Switzerland
Pages 1-7 | Received 08 Jun 1992, Accepted 19 Oct 1992, Published online: 15 Nov 2016

REFERENCES

  • Jefford, C. W. (1991). 1,2,4-Trioxanes, the chemistry of a new class of saturated heterocycles. In Dioxygen Activation and Homogeneous Catalytic Oxidation, ed. Simandi, L. I., pp. 555–564. Amsterdam: Elsevier.
  • Jefford, C. W., McGoran, E. C., Boukouvalas, J., Richardson, G., Robinson, B. L. & Peters, W. (1988). Synthesis of new 1,2,4-trioxanes and their antimalarial activity. Helvetica Chimica Acta, 71, 1805–1812.
  • Peters, W. (1987). Chemotherapy and Drug Resistance in Malaria, 2nd edn. London: Academic Press.
  • Peters, W. (1990). Plasmodium: resistance to antimalarial drugs. Annales de Parasitologie Humaine et Comparée, (Suppl. I) 65, 103–106.
  • Peters, W., Chance, M., Lissner, R., Momen, H. & Warhurst, D. C. (1978). The chemotherapy of rodent malaria XXX. The enigmas of the ‘NS’ lines of P. berghei. Annals of Tropical Medicine and Parasitology, 72, 23–36.
  • Peters, W., Davies, E. E. & Robinson, B. L. (1975). The chemotherapy of rodent malaria XXIII. Causal prophylaxis, part II: Practical experience with Plasmodium yoelii nigeriensis in drug screening. Annals of Tropical Medicine and Parasitology, 69, 311–328.
  • Peters, W. & Robinson, B. L. (1992). The chemotherapy of rodent malaria. XLVII. Studies on pyronaridine and other Mannich base antimalarials. Annals of Tropical Medicine and Parasitology, 86, 455–465.
  • Peters, W., Robinson, B. L., Rossier, J. C., Misra, D. & Jefford C. W. (1993). The chemotherapy of rodent malaria. XLIX. The activities of some synthetic 1,2,4-trioxanes against choroquine-sensitive and choroquine-resistant parasites. Part 2: Structure-activity studies on cis-fused cyclopenteno-1,2,4-trioxanes (genozans) against drug-sensitive and drug-resistant lines of Plasmodium berghei and P. yoelii ssp. NS in vivo. Annals of Tropical Medicine and Parasitology, 87, 9–16.
  • Wellems, T. E. (1991). Molecular genetics of drug resistance in Plasmodium falciparum malaria. Parasitology Today, 7, 110–112.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.