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Original Articles

Particle Penetration and Clearance in the Human Lung

Results in Healthy Subjects and Subjects With Chronic Bronchitis

&
Pages 214-219 | Received 14 Mar 1974, Accepted 24 Apr 1974, Published online: 29 Apr 2013

References

  • Thomson , ML and Short , MD . 1969 . Mucociliary function in health, chronic obstructive airway disease, and asbestosis . J Appl Physiol , 26 : 535 – 539 .
  • et al. Pulmonary mucociliary clearance in cystic fibrosis New Engl J Med 1973 288 651 654
  • May , KR . 1949 . An improved spinning top homogeneous spray apparatus . J Appl Phys , 20 : 932 – 938 .
  • Few , JD , Short , MD and Thomson , ML . 1970 . Preparation of 99mTc labelled particles for aerosol studies . Radiochem Radioanal Letters , 5 : 275 – 277 .
  • et al. An inexpensive automatic two-detector lung scanner Phys Med Biol 1971 16 691 692
  • et al. Elimination of 5μ particles from the human lung Nature 1967 215 30 33
  • Cotes , JE . 1968 . Lung Function , 2 , Oxford , , England : Blackwell Scientific Publications .
  • Milne , JS and Williamson , J . 1972 . Respiratory function in older people . Clin Sci , 42 : 371 – 381 .
  • Pavia , D , Short , MD and Thomson , ML . 1970 . No demonstrable long term effects of tobacco smoking on the mucociliary mechanism of the human lung . Nature , 226 : 1228 – 1231 .
  • Pavia , D and Thomson , ML . 1970 . Unimpaired mucociliary clearance in the lung of a centenarian smoker . Lancet , 1 : 449 – 450 .
  • et al. Study of lung structure and function with aerosols Ninth Annual Report of Progress of the Institute of Environmental Medicine Kneip TJ New York University Medical Center 1972 98 101 in
  • Asmundsson , T and Kilbum , KH . 1970 . Mucociliary clearance rates at various levels in dog lungs . Am Rev Resp Dis , 102 : 388 – 397 .
  • Hatch , TF and Gross , P . 1964 . Pulmonary Deposition and Retention of Inhaled Aerosols , London : Academic Press Inc .
  • Lippmann , M , Albert , RE and Peterson , HT Jr . 1971 . “ The regional deposition of inhaled aerosols in man ” . In Inhaled Particles: III , Edited by: Walton , WH . Vol. 1 , 123 – 130 . Old Woking, Surrey , , England : Unwin Bros Ltd . in
  • Stuart , BO . 1973 . Deposition of inhaled aerosols . Arch Intern Med , 131 : 60 – 73 .
  • Morrow , PE . 1973 . Alveolar clearance of aerosols . Arch Intern Med , 131 : 101 – 108 .
  • Goldberg , IS and Lourenco , RV . 1973 . Deposition of aerosols in pulmonary disease . Arch Intern Med , 131 : 88 – 91 .
  • et al. Effect of chronic obstructive pulmonary disease on, rate of deposition of aerosols in the lung during breath holding Inhaled Particles: III Walton WH Unwin Bros Ltd Old Woking, Surrey , , England 1971 1 123 130 in
  • Owen , PR . 1969 . “ Turbulent flow and particle deposition in the trachea ” . In Circulatory and Respiratory Mass Transport (A Ciba Foundation Symposium) , Edited by: Wolstenholme , GEW and Knight , J . 236 – 252 . London : J & A Churchill Ltd . in
  • Altshuler , B . 1969 . “ Behaviour of airborne particles in the respiratory tract ” . In Circulatory and Respiratory Mass Transport (A Ciba Foundation Symposium) , Edited by: Wolstenholme , GEW and Knight , J . 215 – 231 . London : J & A Churchill Ltd . in
  • Davies , CN . 1972 . Breathing of half-micron aerosols: II. Interpretation of experimental results . J Appl Physiol , 32 : 601 – 611 .
  • Briscoe , WA , Forster , RE and Comroe , JH Jr . 1954 . Alveolar ventilation at very low tidal volumes . J Appl Physiol , 7 : 27 – 30 .
  • Dolfuss , RE , Milic-Emili , J and Bates , DV . 1967 . Regional ventilation of the lung, studied with boluses of 133Xenon . Respir Physiol , 2 : 234 – 246 .
  • Arnott , WM , Clarke , SW and Jones , JG . 1971 . Mass movement of gas in respiratory tubes . Progr Resp Res , 6 : 2 – 14 .
  • Lippmann , M and Albert , RE . 1969 . The effect of particle size on the regional deposition of inhaled aerosols in the human respiratory tract . Am Ind Hyg Assoc J , 30 : 257 – 275 .
  • et al. Regional distribution of ventilation and perfusion in elderly subjects J Clin Invest 1968 47 81 92
  • et al. Airway closure as a function of age Respir Physiol 1969/1970 8 58 65
  • et al. Measurement of “closing volume” as a simple and sensitive test for early detection of small airway disease Am J Med 1972 52 747 753
  • Hogg , JC , Macklem , PT and Thurlbeck , WM . 1968 . Site and nature of airway obstruction in chronic obstructive lung disease . New Engl J Med , 278 : 1355 – 1360 .
  • et al. Bronchial deposition and clearance of aerosols Arch Intern Med 1973 131 115 127
  • Macklem , PT and Mead , J . 1967 . Resistance of central and peripheral airways measured by a retrograde catheter . J Appl Physiol , 22 : 395 – 401 .
  • Pride , NB . 1971 . The assessment of airflow obstruction . Br J Dis Chest , 65 : 135 – 169 .
  • Thomson , ML and Pavia , D . 1974 . Role of bronchitis in mitigating coal workers’ pneumoconiosis . Lancet , 1 : 225 – 226 .
  • Gough , J . 1960 . Emphysema in relation to occupation . Ind Med Surg , 29 : 283 – 285 .

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