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Archives of Environmental Health: An International Journal Volume 41, 1986 - Issue 1
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Original Articles

The Relationships of Aerosol Deposition, Lung Size, and the Rate of Mucociliary Clearance

Christopher S. Gerrard M.D., Ph.D. The Section of Environmental Medicine and Respiratory and Critical Care Medicine, University of Illinois at Chicago, 1940 W. Taylor Street, Chicago, Illinois, USA; The Department of Medicine and Respiratory Therapy Division of the Department of Anesthesiology, University of Illinois at Chicago, 1940 W. Taylor Street, Chicago, Illinois, USA
,
Timothy R. Gerrity Ph.D. The Section of Environmental Medicine and Respiratory and Critical Care Medicine, University of Illinois at Chicago, 1940 W. Taylor Street, Chicago, Illinois, USA; The Department of Medicine and Respiratory Therapy Division of the Department of Anesthesiology, University of Illinois at Chicago, 1940 W. Taylor Street, Chicago, Illinois, USA
&
Donovan B. Yeates Ph.D. The Section of Environmental Medicine and Respiratory and Critical Care Medicine, University of Illinois at Chicago, 1940 W. Taylor Street, Chicago, Illinois, USA; The Department of Medicine and Respiratory Therapy Division of the Department of Anesthesiology, University of Illinois at Chicago, 1940 W. Taylor Street, Chicago, Illinois, USA
Pages 11-15 | Accepted 24 Jul 1985, Published online: 03 Aug 2010

References

  • Albert , R. E. , Lippman , M. , Peterson , H. T. , Berger , J. , Sanborn , K. and Bohning , D. 1973 . Bronchial deposition and clearance of aerosols . Arch Intern Med , 131 : 115 – 27 .
  • Lee , P. S. , Gerrity , T. R. , Hass , F. J. and Lourenco , R. V. 1979 . A model for tracheobronchial clearance of inhaled particles in man and a comparison with data . IEEE Trans Biomed Engr , 26 : 624 – 30 .
  • Yeates , D. B. , Gerrity , T. R. and Garrard , C. S. 1982 . “ Characteristics of tracheobronchial deposition and clearance in man ” . In Inhaled Particles and Vapours , Edited by: Critchlow , V. 249 – 57 . Oxford : Pergamon Press .
  • Foster , W. M. , Langenback , E. and Bergofsky , E. H. 1980 . Measurement of tracheal and bronchial mucus velocities in man: Relation to lung clearance . J Appl Physiol , 48 : 965 – 71 .
  • Yeates , D. B. , Aspin , N. , Levinson , H. , Jones , M. and Bryan , A. C. 1975 . Mucociliary tracheal transport rates in man . J Appl Physiol , 39 : 487 – 95 .
  • Sanchis , J. , Dolovich , M. B. , Chalmers , R. and Newhouse , M. T. 1972 . Quantitation of regional aerosol clearance in the normal lung . J Appl Physiol , 33 : 757 – 62 .
  • Pavia , D. , Thomson , M. L. and Shannon , H. S. 1977 . Aerosol inhalation and depth of deposition in the human lung . Arch Environ Health , 32 : 131 – 37 .
  • Wilkey , D. D. , Lee , P. S. , Hass , F. J. , Gerrity , T. R. , Yeates , D. B. and Lourenco , R. V. 1980 . Mucociliary clearance of deposited particles from the lung: Intra- and intersubject reproducibility, total and regional clearance, and model comparison . Arch Environ Health , 35 : 294 – 302 .
  • Garrard , C. S. , Gerrity , T. R. , Schreiner , J. F. and Yeates , D. B. 1981 . Analysis of aerosol deposition pattern in the healthy human lung . Arch Environ Health , 36 : 184 – 93 .
  • Albert , R. E. , Lippman , M. and Briscoe , W. 1969 . The characteristics of bronchial clearance in humans and the effect of cigarette smoking . Arch Environ Health , 18 : 738 – 55 .
  • Gerrity , T. R. , Lee , P. S. , Hass , F. J. , Marinelli , A. , Werner , P. and Lourenco , R. V. 1979 . Calculated deposition of particles in the airway generations of normal subjects . J Appl Physiol , 47 ( 4 ) : 867 – 73 .
  • Pavia , D. , Short , M. D. and Thomson , M. L. 1970 . No demonstrable long term effects of cigarette smoking on the mucociliary mechanism of the human lung . Nature , 226 : 1228 – 31 .
  • Velasquez , D. J. and Morrow , P. E. 1984 . Estimation of guinea pig tracheobronchial transport rates using a compartmental model . Exp Lung Res , 7 : 163 – 76 .

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