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Archives of Environmental Health: An International Journal Volume 42, 1987 - Issue 2
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Original Articles

Elevated Urinary Excretion of β-Aminoisobutyric Acid and Exposure to Inorganic Lead

Walter R. Farkas Ph.D. Department of Environmental Practice, University of Tennessee College of Veterinary Medicine, Knoxville, Tennessee, USA
,
Alf Fischbein M.D. Division of Environmental and Occupational Medicine, Mount Sinai School of Medicine of the City University of New York, New York, New York, USA
,
Stephen Solomon Ph.D. Department of Neoplastic Diseases and Biomathematical Sciences, Mount Sinai School of Medicine of the City University of New York, New York, New York, USA
,
Frank Buschman B.A. Department of Molecular Biology, AMC Cancer Research Center, Denver, Colorado
,
Ernest Borek Ph.D., M.D. (Hon.C.) Department of Molecular Biology, AMC Cancer Research Center, Denver, Colorado
&
Opendra K. Sharma Ph.D. Department of Molecular Biology, AMC Cancer Research Center, Denver, Colorado
Pages 96-99 | Received 20 Feb 1986, Accepted 12 Aug 1986, Published online: 03 Aug 2010

References

  • Committee on Lead in the Human Environment . 1980 . Lead in the Human Environment , Washington, D.C. : Environmental Studies Board, Commission on Natural Resources, National Research Council, National Academy of Sciences .
  • Needleman , H. L. , Gunnoe , C. , Leviton , A. , Reed , R. , Peresie , H. , Maher , C. and Barrett , P. 1979 . Deficits in psychologic and classroom performance of children with elevated dentine lead levels . N Engl J Med , 300 : 689 – 95 .
  • Baker , E. L. Jr. , Landrigan , P. J. , Barbour , A. C. , Cox , D. H. , Folland , D. S. , Ligo , R. N. and Throckmorton , J. 1979 . Occupational lead poisoning in the United States: Clinical and biochemical findings related to blood lead levels . Br J Ind Med , 36 : 314 – 22 .
  • Lilis , R. , Fischbein , A. , Eisinger , J. , Blumberg , W. E. , Diamond , S. , Anderson , H. A. , Rom , W. , Rice , C. , Sarkozi , L. , Kon , S. and Selikoff , I. J. 1977 . Prevalence of lead disease among secondary lead smelter workers and biological indicators of lead exposure . Environ Res , 14 : 255 – 85 .
  • Lamola , A. A. and Yamane , T. 1974 . Zinc protoporphyrin in the erythrocytes of patients with lead intoxication and iron deficiency anemia . Science , 186 : 936 – 38 .
  • Granick , J. L. , Sassa , S. , Granick , S. , Levere , R. D. and Kappas , A. 1973 . Studies in lead poisoning. II. Correlation between the ratio of activated to inactivated δ-aminolevulinic acid dehydratase of whole blood and the blood lead level . Biochem/Vfeef , 8 : 149 – 59 .
  • Schwanitz , G. , Lehnert , G. and Gebhart , E. 1970 . Chromosomenschaden bei beruflicher Bleibelastung. (Chromosome damage in occupational exposure to lead.) . J Dtsch Med Wochenschr , 95 : 1636 – 41 .
  • Forni , A. , Cambiaghi , G. and Secchi , G. C. 1976 . Initial occupational exposure to lead: Chromosome and biochemical findings . Arch Environ Health , 31 : 73 – 78 .
  • Nordenson , I. , Beckman , G. , Beckman , L. and Nordstrom , S. 1978 . Occupational and environmental risks in and around a smelter in northern Sweden. IV. Chromosomal aberrations in workers exposed to lead . Hereditas , 88 : 263 – 67 .
  • Muro , L. A. and Goyer , R. A. 1969 . Chromosome damage in experimental lead poisoning . Arch Pathol , 87 : 660 – 63 .
  • Weller , C. V. 1951 . The blastophthoric effect of chronic lead poisoning . J Med Res , 33 : 271 – 93 .
  • Ferm , V. H. and Carpenter , S. J. 1967 . Developmental malformations resulting from the administration of lead salts . Exp Mol Pathol , 7 : 208 – 13 .
  • Borek , E. , Sharma , O. K. , Fischbein , A. , Selikoff , I. and Farkas , W. Elevated excretion of β-aminoisobutyric acid in the urine of subjects with excessive exposure to lead . 12th International Congress Biochemistry . Perth. pp. 235
  • Fischbein , A. , Daurn , S. M. , Davidow , B. , Slavin , G. , Alvares , A. P. , Sassa , S. , Anderson , K. E. , Kappas , A. , Eisinger , J. , Blumberg , W. E. , Winicow , E. H. and Selikoff , I. J. 1978 . Lead hazard among ironworkers. Dismantling lead-painted elevated subway line in New York City. N.Y. State . J Med , 78 : 1250 – 59 .
  • Blu*rnberg , W. E. , Eisinger , J. , Lamola , A. A. and Zuckerman , D. M. 1978 . Zinc protoporphyrin level in blood determined by a portable hematofluororneter: A screening device for lead poisoning . J Lab Clin Med , 89 : 712 – 23 .
  • Clapp , N. K. and Tardif , S. D. Digestive Diseases and Science in press
  • Buschman , F. L. , Apell , G. and Sharma , O. K. 1986 . High-performance liquid chromatographic determination of β-aminoisobutyric acid in the picomole range . J Chromat , 374 : 129 – 36 .
  • Nilsen , H. R. , Sjolin , K. E. , Nyhol*rn , K. , Baliga , B. S. , Wong , R. and Borek , E. 1974 . β-aminoisobutyric acid, a new probe for the metabolism of DNA and RNA in normal and tumorous tissue . Cancer Res , 34 : 1381 – 84 .
  • Sutton , H. E. 1960 . The Metabolic Basis of Inherited Disease , 792 New York : McGraw-Hill .
  • Armstrong , M. D. , Yates , K. , Kakimoto , Y. , Taniguchi , K. and Kappe , T. 1963 . Excretion of β-aminoisobutyric acid by man . J Biol Chem , 238 : 1447 – 55 .
  • Waalkes , T. P. , Gehrke , C. W. , Lakings , D. B. , Zumwalt , R. W. , Kuo , K. C. , Jacobs , S. A. and Borek , E. 1976 . β-aminoaciduria in patients with Burkitt's lymphoma . J Natl Cancer Inst , 57 : 435
  • Wilson , V. K. , Thomson , M. L. and Dent , C. E. 1953 . Aminoaciduria in lead poisoning. A case in childhood . Lancet , ii : 66 – 68 .
  • Borek , E. , Sharma , O. K. and Waalkes , T. P. 1983 . New applications of urinary nucleoside markers. Recent results . Cancer Res , 84 : 301 – 16 .

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