Clinico-pathomorphological, serum biochemical and histological studies in broilers fed ochratoxin A and a toxin deactivator (Mycofix® Plus)

References

• Agawane , SB and Lonkar , PS . 2004 . Effect of probiotic containing Saccharomyces boulardii on experimental ochratoxicosis in broilers: Hematobiochemical studies . Journal of Veterinary Sciences , 5 : 359 – 367 .
   PubMedGoogle Scholar
• Aleksandrov , M and Dzhurov , A . 1987 . Effect of ochratoxin on the health status of broilers . Veterinarno-meditsinski nauki , 24 : 38 – 43 .
   PubMedGoogle Scholar
• Alex , JB and Steward-Brown , B . 2003 . “ Disease prevention and diagnosis ” . In Diseases of Poultry , 11th , Edited by: Saif , YM , Barnes , HJ , Fadly , AM , Glisson , JR , Mcdougald , LR and Swayne , DE . 47 USA : Ames, IA, Iowa State Press .
   Google Scholar
• Bhanuprakash , Sathyanarayana , ML , Vijayasarathi , SK and Upendra , HA . 2006 . Serum biochemistry, organ weights and performance of broiler chickens fed aflatoxins, ochratoxin and toxin binder . Indian Veterinary Journal , 83 : 159 – 161 .
   Google Scholar
• Binder , EM , Heidler , D , Schatzmayr , G , Thimm , N , Fuchs , E , Schuh , M , Karska , R and Binder , J . 21–25 May 2000 . “ Mycotoxins and phycotoxins in perspective at the turn of the millennium ” . In Proceedings of the 10th International IUPAC Symposium on Mycotoxins and Phycotoxins Edited by: de koe , WJ , Samson , RA , van egmond , HP , Gilbert , J and Sabino , M . 21–25 May , 271 – 277 . Guaruj a, , Brazil
   Google Scholar
• Creppy , EE , Schlegel , M , Roschenthaler , R and Dirheimer , G . 1980 . Phenylalanine prevents acute poisoning by ochratoxin A in mice . Toxicology Letters , 60 : 77 – 80 .
   Web of Science ®Google Scholar
• Dwivedi , P and Burns , RB . 1984 . Pathology of ochratoxin A in young broiler chicks . Research in Veterinary Science , 36 : 92 – 103 .
   PubMed Web of Science ®Google Scholar
• Dwivedi , P and Burns , RB . 1986 . The natural occurrence of ochratoxin A and its effects in poultry. A review: Part I. Epidemiology and toxicity . World's Poultry Science Journal , 42 : 32 – 47 .
   Web of Science ®Google Scholar
• Elaroussi , MA , Mohamed , FR , El Barkouky , EM , Atta , AM , Abdou , AM and Hatab , H . 2006 . Experimental ochratoxicosis in broiler chicken . Avian Pathology , 35 : 263 – 269 .
   PubMed Web of Science ®Google Scholar
• Fuchs , R . 1988 . “ Distribution and fate of ochratoxin A in experimental animals ” . In Doctoral thesis , 13 – 41 . Uppsala Sweden : Swedish University of Agricultural Science .
   Google Scholar
• Fuchs , E , Binder , EM , Heidler , D and Karska , R . 2002 . Structural characterization of metabolites after the microbial degradation of Type A trichothecenes by the bacterial strain BBSH 797 . Food Additive Contaminants , 19 : 379 – 386 .
   PubMed Web of Science ®Google Scholar
• Gibson , RM , Bailey , CA , Kubena , LF , Huff , WE and Harvey , RB . 1990 . Impact of L-phenylalanine supplementation on the performance of three week old broilers fed diet containing Ochratoxin A. 1. Effect on body weight, feed conversion, relative organ weight and mortality . Poultry Science , 69 : 414 – 419 .
   PubMed Web of Science ®Google Scholar
• Godbole , SM , Kalorey , DR , Ingel , VC , Kurkure , NV , Ganorkar , AG and Harne , SD . 2001 . Effect of Growell during induced aflatoxicosis in chicks: Growth and hematological studies . Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases , 22 : 183 – 185 .
   Google Scholar
• Hamilton , PB , Huff , WE , Harris , JR and Wyatt , RD . 1982 . Natural occurrences of ochratoxicosis in poultry . Poultry Science , 61 : 1832 – 1841 .
   PubMed Web of Science ®Google Scholar
• Harvey , RB , Elissalde , MH and Kubena , LK . 1992 . Immunotoxicity of ochratoxin A to growing gilts . American Journal of Veterinary Research , 53 : 187 – 207 .
   Web of Science ®Google Scholar
• Hofstetter , U , Starkl , V and Sarandan , H . 2006 . Successful detoxification of ochratoxin A and deoxynivalenol in growing broiler chicken . World's Poultry Science , 62 ( Suppl. ) : 132 – 133 . Proceedings EPC Verona, Italy
   Google Scholar
• Jelena , BN , Bocarov-stancic , AS and Sinovec , ZJ . 2005 . “ Pathohistological changes in kidney and LDH activity in broiler treated with different doses of ochratoxin A ” . In Proceedings for Natural Sciences Matica Srpska 103 – 108 .
   Google Scholar
• Kuiper-Goodman , T and Scott , PM . 1989 . Risk assessment of mycotoxin ochratoxin A . Biomedical and environmental Sciences , 2 : 179 – 248 .
   PubMedGoogle Scholar
• Kurkure , NV , Harvey , RB , Phillip , TD and Clement , BA . 2000 . Ameliorative effect of turmeric (curcuma longa) in induced aflatoxicosis in cockerels . Indian Journal of Veterinary Pathology , 24 : 26 – 28 .
   Google Scholar
• Marquardt , RR and Frohlich , AA . 1992 . A review of recent advances in understanding ochratoxicosis . Journal of Animal Sciences , 70 : 3968 – 3988 .
   PubMed Web of Science ®Google Scholar
• Micheluzzi , L . 2004 . Effect of Mycofix Plus in diets contaminated with Aflatoxin, T-2 toxin and ochratoxin on broiler (Trial 04111231 – BIOMIN GmbH, Austria)
   Google Scholar
• Mohiudin , SM , Warasi , SMA and Reddy , MV . 1993 . Hematological and biochemical changes in the broiler chicken . Indian Veterinary Journal , 70 : 613 – 617 .
   Google Scholar
• Molnar , O , Schatzmayr , G , Fuch , E and Prillinger , H . 2004 . Trichosporon mycotoxinivorans sp. Nov., a new yeast species useful in detoxification of various mycotoxins . Systematic and Applied Microbiology , 27 : 661 – 671 .
   PubMed Web of Science ®Google Scholar
• Pittet , A . 1998 . Natural occurrence of mycotoxins in foods and feeds – an updated review . Revuede Medicine Veteinaire , 149 : 479 – 492 .
   Web of Science ®Google Scholar
• Politis , I , Fegeros , K , Nitsch , S , Schatzmayr , G and Kanatas , D . 2005 . Use of Trichosporon mycotoxinivorans to suppress the effects of ochratoxicosis on the immune system of broiler chicks . British Poultry Science , 46 : 1 – 8 .
   PubMed Web of Science ®Google Scholar
• Raju , MVLN and Devegowda , G . 2000 . influence of esterified glucomannan on performance and organ morphology, serum biochemistry and hematology in broilers exposed to individual and combined mycotoxicosis (aflatoxin, ochratoxin and T-2 toxin) . British Poultry Science , 41 : 640 – 650 .
   PubMed Web of Science ®Google Scholar
• RamaDevi , V , Gopal Naidu , NR and Ravikumar , P . 2000 . An assessment of protective effect of bentonite on ochratoxicosis in broilers with reference to certain hematobiochemical profiles . Indian veterinary Journal , 77 : 303 – 306 .
   Web of Science ®Google Scholar
• Sakhare , PS , Harne , SD , Kalorey , DR , Warke , SR , Bhandarkar , AG and Kurkure , NV . 2007 . Effect of Toxiroak polyherbal feed supplement during induced aflatoxicosis, ochratoxicosis and combined mycotoxicosis in broilers . Veterinarski Arhiv , 77 : 129 – 146 .
   Google Scholar
• Santin , E , Paulillo , AC , Maiorka , PC , Alessi , AC , Krabbe , EL and Maiorka , A . 2002 . The effects of ochratoxin/aluminosilicate interaction on the tissues and humoral immune response of broilers . Avian Pathology , 31 : 73 – 79 .
   PubMed Web of Science ®Google Scholar
• Santin , E , Paulillo , AC , Nakagui , LSO , Alessi , AC , Polveiro , WJC and Maiorka , A . 2003 . Evaluation of cell wall yeast as adsorbent of ochratoxin in broiler diets . International Journal of Poultry Science , 2 : 372 – 378 .
   Google Scholar
• Schatzmayr , G , Heidler , D , Fuch , E , Nitsch , S , Mohnl , M , Taubel , M , Loibner , AP , Brain , R and Binder , EM . 2003 . “ Investigation of different yeast strains for the detoxification of ochratoxin A ” . In 25th Mycotoxin Workshop , Germany : Giessen .
   Google Scholar
• Scheur , PJ and Chalk , BT . 1986 . Clinical tests: Histopathology , London : Wolfe Medical Publications .
   Google Scholar
• Singh , GSP , Chauhan , HVS , Jha , GH and Singh , KK . 1990 . Immunosuppression due to chronic ochratoxicosis in broiler chicks . Journal of Comparative Pathology , 103 : 399 – 410 .
   PubMed Web of Science ®Google Scholar
• Stoev , SD , Anguelov , G , Ivanov , I and Pavlov , D . 2000 . Influence of ochratoxin A and an artichoke on the vaccinal immunity and health in broiler chicks . Experimental Toxicological Pathology , 52 : 43 – 55 .
   PubMed Web of Science ®Google Scholar
• Stoev , SD , Djuvinov , D , Mirtcheva , T , Pavlov , D and Mantle , G . 2002 . Studies on some feed additives giving partial protection against ochratoxin A toxicity in chicks . Toxicology Letters , 135 : 33 – 50 .
   PubMed Web of Science ®Google Scholar
• Stoev , SD , Stefanov , M , Denev , S , Radic , B , Domijan , AM and Peraica , M . 2004 . Experimental mycotoxicosis in chicken induced by ochratoxin A and Penicillic acid and intervention with natural plant extracts . Veterinary Research Communications , 28 : 727 – 746 .
   PubMed Web of Science ®Google Scholar
• Watts , CM , Chen , YC , Ledoux , DR , Broomhead , JN , Bermudez , AJ and Rottingus , GE . 2003 . Effects of multiple mycotoxins and a hydrated sodium calcium aluminosilicate in poultry . International Journal of Poultry Science , 2 : 372 – 378 .
   Google Scholar
• Verma , J , Johri , TS , Swain , BK and Ameena , S . 2004 . Effect of graded levels of aflatoxin, ochratoxin and their combinations on the performance and immune response of broilers . British Poultry Sciences , 45 ( 4 ) : 512 – 518 .
   PubMed Web of Science ®Google Scholar