Unexpected consequences of genetic selection in broilers and turkeys: problems and solutions

REFERENCES

• Abourachid, A. (1991) Comparative gait analysis of 2 strains of turkey, Meleagris gallopavo. British Poultry Science, 32: 271–277.
   PubMed Web of Science ®Google Scholar
• Abourachid, A. (1993) Mechanics of standing in birds – functional explanation of lameness problems in giant turkeys. British Poultry Science, 34: 887–898.
   PubMed Web of Science ®Google Scholar
• Abplanalp, H., Lowry, D.C. & Van Middelkoop, J.H. (1977) Selection for increased incidence of double-yolked egg in white leghorn chickens. British Poultry Science, 18: 585–595.
   Web of Science ®Google Scholar
• Alvarez, R. & Hocking, P.M. (2007) Stochastic model of egg production in broiler breeders. Poultry Science, 86: 1445–1452.
   PubMed Web of Science ®Google Scholar
• Alvarez, R. & Hocking, P.M. (2009) Stochastic modelling of optimum initial body weight, daily weight gain and effect of genetic changes in ovulation rate and age at sexual maturity on total egg production of broiler breeders. British Poultry Science, 50: 135–143.
   PubMed Web of Science ®Google Scholar
• Alvarez, R. & Hocking, P.M. (2012) Changes in ovarian function and egg production in commercial broiler breeders through 40 weeks of lay. British Poultry Science, 53: 396–393.
   Web of Science ®Google Scholar
• Asher, L., Diesel, G., Summers, J.F., McGreevy, P.D. & Collins, L.M. (2009) Inherited defects in pedigree dogs. Part 1: Disorders related to breed standards. Veterinary Journal, 182: 402–411.
   PubMed Web of Science ®Google Scholar
• Ask, B. (2010) Genetic variation of contact dermatitis in broilers. Poultry Science, 89: 866–875.
   PubMed Web of Science ®Google Scholar
• Beilharz, R.G., Luxford, B.G. & Wilkinson, J.L. (1993) Quantitative genetics and evolution – is our understanding of genetics sufficient to explain evolution. Journal of Animal Breeding and Genetics – Zeitschrift Fur Tierzuchtung Und Zuchtungsbiologie, 110: 161–170.
   PubMed Web of Science ®Google Scholar
• Bornstein, S., Plavnik, I. & Lev, Y. (1984) Body-weight and or fatness as potential determinants of the onset of egg-production in broiler breeder hens. British Poultry Science, 25: 323–341.
   PubMed Web of Science ®Google Scholar
• Brand, C.L., Kingan, S.B., Wu, L. & Garrigan, D. (2013) A selective sweep across species boundaries in drosophila. Molecular Biology and Evolution, 30: 2177–2186.
   PubMed Web of Science ®Google Scholar
• Brody, T.B., Siegel, P.B. & Cherry, J.A. (1984) Age, body-weight and body-composition requirements for the onset of sexual maturity of dwarf and normal chickens. British Poultry Science, 25: 245–252.
   PubMed Web of Science ®Google Scholar
• Broom, D.M. (1991) Animal-welfare – concepts and measurement. Journal of Animal Science, 69: 4167–4175.
   PubMed Web of Science ®Google Scholar
• Buchanan, S., Robertson, G.W. & Hocking, P.M. (2001) Ovarian steroid hormone production in a multiple ovulating male line and a single ovulating traditional line of turkeys. Reproduction, 121: 277–285.
   PubMed Web of Science ®Google Scholar
• Chen, C.Y., Misztal, I., Aguilar, I., Tsuruta, S., Meuwissen, T.H.E., Aggrey, S.E., Wing, T. & Muir, W.M. (2011) Genome-wide marker-assisted selection combining all pedigree phenotypic information with genotypic data in one step: an example using broiler chickens. Journal of Animal Science, 89: 23–28.
   PubMed Web of Science ®Google Scholar
• Corr, S.A., Gentle, M.J., McCorquodale, C.C. & Bennett, D. (2003a) The effect of morphology on the musculoskeletal system of the modern broiler. Animal Welfare, 12: 145–157.
   Web of Science ®Google Scholar
• Corr, S.A., Gentle, M.J., McCorquodale, C.C. & Bennett, D. (2003b) The effect of morphology on walking ability in the modern broiler: a gait analysis study. Animal Welfare, 12: 159–171.
   Web of Science ®Google Scholar
• Duff, S.R.I. (1985) Further-studies of degenerative hip disease – antitrochanteric degeneration in turkeys and broiler type chickens. Journal of Comparative Pathology, 95: 113–122.
   PubMed Web of Science ®Google Scholar
• Duff, S.R.I. & Hocking, P.M. (1986) Chronic orthopedic disease in adult male broiler breeding fowls. Research in Veterinary Science, 41: 340–348.
   PubMed Web of Science ®Google Scholar
• Duff, S.R.I., Hocking, P.M. & Field, R.K. (1987) The gross morphology of skeletal disease in adult male breeding turkeys. Avian Pathology, 16: 635–651.
   PubMed Web of Science ®Google Scholar
• Duff, S.R.I. & Lynch, M. (1988) Antitrochanteric and acetabular lesions in adult male breeding turkeys. Avian Pathology, 17: 121–137.
   PubMed Web of Science ®Google Scholar
• Duncan, I.J.H., Beatty, E.R., Hocking, P.M. & Duff, S.R.I. (1991) Assessment of pain associated with degenerative hip disorders in adult male turkeys. Research in Veterinary Science, 50: 200–203.
   PubMed Web of Science ®Google Scholar
• Dunn, I.C., Meddle, S.L., Wilson, P.W., Wardle, C.A., Law, A.S., Bishop, V.R., Hindar, C., Robertson, G.W., Burt, D.W., Ellison, S.J.H., Morrice, D.M. & Hocking, P.M. (2013) Decreased expression of the satiety signal receptor cckar is responsible for increased growth and body weight during the domestication of chickens. American Journal of Physiology – Endocrinology and Metabolism, 304: E909–E921.
   PubMed Web of Science ®Google Scholar
• Dunnington, E.A., Honaker, C.F., McGilliard, M.L. & Siegel, P.B. (2013) Phenotypic responses of chickens to long-term, bidirectional selection for juvenile body weight-historical perspective. Poultry Science, 92: 1724–1734.
   PubMed Web of Science ®Google Scholar
• EFSA (2010) Scientific opinion on the influence of genetic parameters on the welfare and resistance to stress of commercial broilers. EFSA Journal, 8: 1662.
   Google Scholar
• EFSA (2012) Scientific opinion on the use of animal-based measures to assess welfare of broilers. EFSA Journal, 10: 2774 pp.
   Google Scholar
• Falconer, D.S. & MacKay, T.F.C. (1996) Introduction to Quantitative Genetics. 4th edn. (Harlow, Pearson Prentice Hall).
   Google Scholar
• Frankham, R. (2008) Genetic adaptation to captivity in species conservation programs. Molecular Ecology, 17: 325–333.
   PubMed Web of Science ®Google Scholar
• Frankham, R. (2009) Genetic architecture of reproductive fitness and its consequences, in: Van der Werf, J., Graser, H.U., Frankham, R. & Gondro, C. (Eds) Adaptation and Fitness in Animal Populations, pp 15–39 (Springer).
   Google Scholar
• Frankham, R., Yoo, B.H. & Sheldon, B.L. (1988) Reproductive fitness and artificial selection in animal breeding – culling on fitness prevents a decline in reproductive fitness in lines of drosophila-melanogaster selected for increased inebriation time. Theoretical and Applied Genetics, 76: 909–914.
   PubMed Web of Science ®Google Scholar
• Hillier, L.W., Miller, W., Birney, E., Warren, W., Hardison, R.C., Ponting, C.P., Bork, P., Burt, D.W., Groenen, M.A.M., Delany, M.E., Dodgson, J.B., Chinwalla, A.T., Cliften, P.F., Clifton, S.W., Delehaunty, K.D., Fronick, C., Fulton, R.S., Graves, T.A., Kremitzki, C., Layman, D., Magrini, V., McPherson, J.D., Miner, T.L., Minx, P., Nash, W.E., Nhan, M.N., Nelson, J.O., Oddy, L.G., Pohl, C.S., Randall-Maher, J., Smith, S.M., Wallis, J.W., Yang, S.P., Romanov, M.N., Rondelli, C.M., Paton, B., Smith, J., Morrice, D., Daniels, L., Tempest, H.G., Robertson, L., Masabanda, J.S., Griffin, D.K., Vignal, A., Fillon, V., Jacobbson, L., Kerje, S., Andersson, L., Crooijmans, R.P.M., Aerts, J., van der Poel, J.J., Ellegren, H., Caldwell, R.B., Hubbard, S.J., Grafham, D.V., Kierzek, A.M., McLaren, S.R., Overton, I.M., Arakawa, H., Beattie, K.J., Bezzubov, Y., Boardman, P.E., Bonfield, J.K., Croning, M.D.R., Davies, R.M., Francis, M.D., Humphray, S.J., Scott, C.E., Taylor, R.G., Tickle, C., Brown, W.R.A., Rogers, J., Buerstedde, J.M., Wilson, S.A., Stubbs, L., Ovcharenko, I., Gordon, L., Lucas, S., Miller, M.M., Inoko, H., Shiina, T., Kaufman, J., Salomonsen, J., Skjoedt, K., Wong, G.K.S., Wang, J., Liu, B., Wang, J., Yu, J., Yang, H.M., Nefedov, M., Koriabine, M., DeJong, P.J., Goodstadt, L., Webber, C., Dickens, N.J., Letunic, I., Suyama, M., Torrents, D. & von Mering, C. (2004) Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature, 432: 695–716.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. (1988) Effects of restricting body weight gain or limiting the photoperiod during rearing on sexual maturity, viability and semen production in large white turkey males. British Poultry Science, 29: 531–544.
   Web of Science ®Google Scholar
• Hocking, P.M. (1990) The relationship between dietary crude protein, bodyweight and fertility in naturally mated broiler breeder males. British Poultry Science, 31: 743–757.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. (1992) Genetic and environmental control of ovarian function in turkeys at sexual maturity. British Poultry Science, 33: 437–448.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. (1994) Assessment of the welfare of food restricted male broiler breeder poultry with musculoskeletal disease. Research in Veterinary Science, 57: 28–34.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. (1996) The role of body weight and food intake after photostimulation on ovarian function at first egg in broiler breeder females. British Poultry Science, 37: 841–851.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. (2009) Feed restriction, in: Hocking, P.M. (Ed) Biology of Breeding Poultry, Vol. 29. Poultry Science Symposium, pp. 307–330 (Abingdon: CABI).
   Google Scholar
• Hocking, P.M. (2010) Genetics of metabolic diseases in poultry, in: Bishop, S.C., Axford, R.F.E., Nicholas, F.W. & Owen, J.B. (Eds) Breeding for Disease Resistance in Farm Animals (Wallingford: CABI).
   Google Scholar
• Hocking, P.M. & Bernard, R. (1997) Effects of male body weight, strain and dietary protein content on fertility and musculo-skeletal disease in naturally mated broiler breeder males. British Poultry Science, 38: 29–37.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. & Bernard, R. (1998) Comparative development of the ovary and production, fertility and hatchability of eggs from traditional turkeys and a contemporary male-line fed ad libitum or restricted. British Poultry Science, 39: 291–297.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M., Bernard, R. & Maxwell, M.H. (1999) Assessment of pain during locomotion and the welfare of adult male turkeys with destructive cartilage loss of the hip joint. British Poultry Science, 40: 30–34.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M., Bernard, R. & Robertson, G.W. (2002) Effects of low dietary protein and different allocations of food during rearing and restricted feeding after peak rate of lay on egg production, fertility and hatchability in female broiler breeders. British Poultry Science, 43: 94–103.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M., Bernard, R. & Wess, T.J. (1998) Comparative development of antitrochanteric disease in male and female turkeys of a traditional line and a contemporary sire-line fed ad libitum or with restricted quantities of food. Research in Veterinary Science, 65: 29–32.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. & McCorquodale, C.C. (2008) Similar improvements in reproductive performance of male line, female line and parent stock broiler breeders genetically selected in the UK or in South America. British Poultry Science, 49: 282–289.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. & Robertson, G.W. (2000) Ovarian follicular dynamics in selected and control (relaxed selection) male- and female-lines of broiler breeders fed ad libitum or on restricted allocations of food. British Poultry Science, 41: 229–234.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. & Robertson, G.W. (2005) Limited effect of intense genetic selection for broiler traits on ovarian function and follicular sensitivity in broiler breeders at the onset of lay. British Poultry Science, 46: 354–360.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M., Sandercock, D.A., Wilson, S. & Fleming, R.H. (2009) Quantifying genetic (co)variation and effects of genetic selection on tibial bone morphology and quality in 37 lines of broiler, layer and traditional chickens. British Poultry Science, 50: 443–450.
   PubMed Web of Science ®Google Scholar
• Hocking, P.M. & Wu, K. (2013) Traditional and commercial turkeys show similar susceptibility to foot pad dermatitis and behavioural evidence of pain. British Poultry Science, 54: 281–288.
   PubMed Web of Science ®Google Scholar
• Hunton, P. (1990) Industrial breeding and selection, in: Crawford, R.D. (Ed) Poultry Breeding and Genetics, 985–1028 (Amsterdam: Elsevier).
   Google Scholar
• Jensen, P., Keeling, L., Schutz, K., Andersson, L., Mormede, P., Brandstrom, H., Forkman, B., Kerje, S., Fredriksson, R., Ohlsson, C., Larsson, S., Mallmin, H. & Kindmark, A. (2005) Feather pecking in chickens is genetically related to behavioural and developmental traits. Physiology & Behavior, 86: 52–60.
   PubMed Web of Science ®Google Scholar
• Kapell, D.N.R.G., Hill, W.G., Neeteson, A.M., McAdam, J., Koerhuis, A.N.M. & Avendano, S. (2012a) Genetic parameters of foot-pad dermatitis and body weight in purebred broiler lines in 2 contrasting environments. Poultry Science, 91: 565–574.
   PubMed Web of Science ®Google Scholar
• Kapell, D.N.R.G., Hill, W.G., Neeteson, A.M., McAdam, J., Koerhuis, A.N.M. & Avendano, S. (2012b) Twenty-five years of selection for improved leg health in purebred broiler lines and underlying genetic parameters. Poultry Science, 91: 3032–3043.
   PubMed Web of Science ®Google Scholar
• Karabozhilova, I., Wieland, B., Alonso, S., Salonen, L. & Hasler, B. (2012) Backyard chicken keeping in the greater London urban area: welfare status, biosecurity and disease control issues. British Poultry Science, 53: 421–430.
   PubMed Web of Science ®Google Scholar
• Karlsson, A.C., Kerje, S., Andersson, L. & Jensen, P. (2010) Genotype at the pmel17 locus affects social and explorative behaviour in chickens. British Poultry Science, 51: 170–177.
   PubMed Web of Science ®Google Scholar
• Kestin, S.C., Knowles, T.G., Tinch, A.E. & Gregory, N.G. (1992) Prevalence of leg weakness in broiler-chickens and its relationship with genotype. Veterinary Record, 131: 190–194.
   PubMed Web of Science ®Google Scholar
• Klasing, K.C., Johnstone, B.J. & Benson, B.N. (1999) Implications of an immune response on growth and nutritional requirements of chicks, in Garnsworthy, P.C. & Wiseman, J. (Eds) Recent Developments in Poultry Nutrition, Vol. 2, pp. 35–47 (Nottingham: Nottingham University Press).
   Google Scholar
• Kranis, A., Gheyas, A.A., Boschiero, C., Turner, F., Yu, L., Smith, S., Talbot, R., Pirani, A., Brew, F., Kaiser, P., Hocking, P.M., Fife, M., Salmon, N., Fulton, J., Strom, T.M., Haberer, G., Weigend, S., Preisinger, R., Gholami, M., Qanbari, S., Simianer, H., Watson, K.A., Woolliams, J.A. & Burt, D.W. (2013) Development of a high-density 600k snp genotyping array for chicken. BMC Genomics, 14: 59.
   PubMed Web of Science ®Google Scholar
• Latter, B.D.H. & Robertson, A. (1962) Effects of inbreeding and artificial selection on reproductive fitness. Genetical Research, 3: 110–138.
   Web of Science ®Google Scholar
• Leopold, A.S. (1944) The nature of heritable wildness in turkeys. Condor, 46: 133–197.
   Google Scholar
• Lillico, S.G., Proudfoot, C., Carlson, D.F., Stverakova, D., Neil, C., Blain, C., King, T.J., Ritchie, W.A., Tan, W., Mileham, A.J., McLaren, D.G., Fahrenkrug, S.C. & Whitelaw, C.B.A. (2013) Live pigs produced from genome edited zygotes. Scientific Reports, 3: 1–4.
   Web of Science ®Google Scholar
• Lyall, J., Irvine, R.M., Sherman, A., McKinley, T.J., Nunez, A., Purdie, A., Outtrim, L., Brown, I.H., Rolleston-Smith, G., Sang, H. & Tiley, L. (2011) Suppression of avian influenza transmission in genetically modified chickens. Science, 331: 223–226.
   PubMed Web of Science ®Google Scholar
• Macdonald, J., Taylor, L., Sherman, A., Kawakami, K., Takahashi, Y., Sang, H.M. & McGrew, M.J. (2012) Efficient genetic modification and germ-line transmission of primordial germ cells using piggybac and tol2 transposons. Proceedings of the National Academy of Sciences of the United States of America, 109: E1466–E1472.
   PubMed Web of Science ®Google Scholar
• Maniatis, G., Demiris, N., Kranis, A., Banos, G. & Kominakis, A. (2013) Model comparison and estimation of genetic parameters for body weight in commercial broilers. Canadian Journal of Animal Science, 93: 67–77.
   Web of Science ®Google Scholar
• Mayne, R.K., Else, R.W. & Hocking, P.M. (2007) High litter moisture alone is sufficient to cause footpad dermatitis in growing turkeys. British Poultry Science, 48: 538–545.
   PubMed Web of Science ®Google Scholar
• McKay, J.C. (2009) The genetics of modern commercial poultry, in Hocking, P.M. (Ed) Biology of Breeding Poultry. Poultry Science Symposium, pp. 3–9 (Abingdon: CABI).
   Google Scholar
• Merritt, E.S. (1968) Genetic parameter estimates for growth and reproductive traits in a randombred control strain of meat type fowl. Poultry Science, 47: 190–199.
   Web of Science ®Google Scholar
• Mercer, J.T. & Hill, W.G. (1984) Estimation of genetic-parameters for skeletal defects in broiler-chickens. Heredity, 53: 193–203.
   Web of Science ®Google Scholar
• Nestor, K.E., Anderson, J.W., Patterson, R.A. & Velleman, S.G. (2008) Genetics of growth and reproduction in the turkey. 17. Changes in genetic parameters over forty generations of selection for increased sixteen-week body weight. Poultry Science, 87: 1971–1979.
   PubMed Web of Science ®Google Scholar
• Nestor, K.E. & Bacon, W. (1972) Production of defective eggs by egg and meat type turkey hens. Poultry Science, 51: 1361–1365.
   Web of Science ®Google Scholar
• Podisi, B.K., Knott, S.A., Burt, D.W. & Hocking, P.M. (2013) Comparative analysis of quantitative trait loci for body weight, growth rate and growth curve parameters from 3 to 72 weeks of age in female chickens of a broiler-layer cross. BMC Genetics, 14: 22.
   PubMed Web of Science ®Google Scholar
• Rauw, W.M., Kanis, E., Noordhuizen-Stassen, E.N. & Grommers, F.J. (1998) Undesirable side effects of selection for high production efficiency in farm animals: A review. Livestock Production Science, 56: 15–33.
   Google Scholar
• Reddy, P.R.K. & Siegel, P.B. (1976) Selection for body weight at eight weeks of age.11. Ovulation and oviposition patterns. Poultry Science, 55: 1518–1530.
   PubMed Web of Science ®Google Scholar
• Rekaya, R., Sapp, R.L., Wing, T. & Aggrey, S.E. (2013) Genetic evaluation for growth, body composition, feed efficiency, and leg soundness. Poultry Science, 92: 923–929.
   PubMed Web of Science ®Google Scholar
• Rubin, C.-J., Zody, M.C., Eriksson, J., Meadows, J.R.S., Sherwood, E., Webster, M.T., Jiang, L., Ingman, M., Sharpe, T., Ka, S., Hallbook, F., Besnier, F., Carlborg, O., Bed’hom, B., Tixier-Boichard, M., Jensen, P., Siegel, P., Lindblad-Toh, K. & Andersson, L. (2010) Whole-genome resequencing reveals loci under selection during chicken domestication. Nature, 464: 587–U145.
   PubMed Web of Science ®Google Scholar
• SCAHAW (2000) The welfare of chickens kept for meat production (broilers). Report of the Scientific Committee on Animal Health and Animal Welfare, European Commission, Health and Consumer Protection Directorate-General, pp. 149.
   Google Scholar
• Schutz, K.E., Kerje, S., Jacobsson, L., Forkman, B., Carlborg, O., Andersson, L. & Jensen, P. (2004) Major growth qtls in fowl are related to fearful behavior: Possible genetic links between fear responses and production traits in a red junglefowl × white leghorn intercross. Behavior Genetics, 34: 121–130.
   PubMed Web of Science ®Google Scholar
• Sheridan, A.K., Howlett, C.R. & Burton, R.W. (1978) Inheritance of tibial dyschondroplasia in broilers. British Poultry Science, 19: 491–499.
   PubMed Web of Science ®Google Scholar
• Siegel, P.B. & Essary, E.O. (1959) Heritabilities and interrelationships of live measurements and eviscerated weight in broilers. Poultry Science, 38: 530–532.
   Web of Science ®Google Scholar
• Siegel, P.B., Honaker, C.F. & Rauw, W.M. (2008) Selection for high production in poultry, in: Rauw, W.M. (ed.) Resource allocation theory applied to farm animal production, pp. 230–242 (CABI Publishing).
   Google Scholar
• Siller, W.G. (1970) Tibial dyschondroplasia in the fowl. Journal of Pathology, 101: 39–46.
   PubMed Web of Science ®Google Scholar
• Summers, J.F., Diesel, G., Asher, L., McGreevy, P.D. & Collins, L.M. (2010) Inherited defects in pedigree dogs. Part 2: disorders that are not related to breed standards. Veterinary Journal, 183: 39–45.
   PubMed Web of Science ®Google Scholar
• Swalander, L.M., Burnside, T.A. & Glover, P.K. (2012) Leg health assessment in commercial turkeys & progress through selection. Lohmann Information, 47: 41–48.
   Google Scholar
• Tatara, M.R., Krupski, W., Jankowski, M., Zdunczyk, Z., Jankowski, J. & Studzinski, T. (2011) Effects of dietary calcium content and vitamin d source on skeletal properties in growing turkeys. British Poultry Science, 52: 718–729.
   PubMed Web of Science ®Google Scholar
• Thomas, C.H., Blow, W.L., Cockerham, C.C. & Glazener, E.W. (1958) The heritability of body weight, gain, feed consumption, and feed conversion in broilers. Poultry Science, 37: 862–869.
   Web of Science ®Google Scholar
• van de Lavoir, M.C., Diamond, J.H., Leighton, P.A., Mather-Love, C., Heyer, B.S., Bradshaw, R., Kerchner, A., Hooi, L.T., Gessaro, T.M., Swanberg, S.E., Delany, M.E. & Etches, R.J. (2006) Germline transmission of genetically modified primordial germ cells. Nature, 441: 766–769.
   PubMed Web of Science ®Google Scholar
• Wang, H., Yang, H., Shivalila, C.S., Dawlaty, M.M., Cheng, A.W., Zhang, F. & Jaenisch, R. (2013) One-step generation of mice carrying mutations in multiple genes by crispr/cas-mediated genome engineering. Cell, 153: 910–918.
   PubMed Web of Science ®Google Scholar
• Whitehead, C.C. (1990) Divergent selection of lean and fat lines of broilers over eight generations of selection using plasma very low density lipoprotein as selection criterion. British Poultry Science, 31: 293–305.
   Web of Science ®Google Scholar
• Whitehead, C.C., McCormack, H.A., McTeir, L. & Fleming, R.H. (2004) High vitamin d-3 requirements in broilers for bone quality and prevention of tibial dyschondroplasia and interactions with dietary calcium, available phosphorus and vitamin a. British Poultry Science, 45: 425–436.
   PubMed Web of Science ®Google Scholar
• Wiener, P. & Wilkinson, S. (2011) Deciphering the genetic basis of animal domestication. Proceedings of the Royal Society B-Biological Sciences, 278: 3161–3170.
   PubMed Web of Science ®Google Scholar
• Wilson, S. (2003) The effects of growth rate and conformation on the skeleton and gait of growing turkeys. Turkeys, 51: 40–41.
   Google Scholar
• Wong, G.K.S., Liu, B., Wang, J., Zhang, Y., Yang, X., Zhang, Z.J., Meng, Q.S., Zhou, J., Li, D.W., Zhang, J.J., Ni, P.X., Li, S.G., Ran, L.H., Li, H., Zhang, J.G., Li, R.Q., Li, S.T., Zheng, H.K., Lin, W., Li, G.Y., Wang, X.L., Zhao, W.M., Li, J., Ye, C., Dai, M.T., Ruan, J., Zhou, Y., Li, Y.Z., He, X.M., Zhang, Y.Z., Huang, X.G., Tong, W., Chen, J., Ye, J., Chen, C., Wei, N., Li, G.Q., Dong, L., Lan, F.D., Sun, Y.Q., Zhang, Z.P., Yang, Z., Yu, Y.P., Huang, Y.Q., He, D.D., Xi, Y., Wei, D., Qi, Q.H., Li, W.J., Shi, J.P., Wang, M.H., Xie, F., Wang, J.J., Zhang, X.W., Wang, P., Zhao, Y.Q., Li, N., Yang, N., Dong, W., Hu, S.N., Zeng, C.Q., Zheng, W.M., Hao, B.L., Hillier, L.W., Yang, S.P., Warren, W.C., Wilson, R.K., Brandstrom, M., Ellegren, H., Crooijmans, R., van der Poel, J.J., Bovenhuis, H., Groenen, M.A.M., Ovcharenko, I., Gordon, L., Stubbs, L., Lucas, S., Glavina, T., Aerts, A., Kaiser, P., Rothwell, L., Young, J.R., Rogers, S., Walker, B.A., van Hateren, A., Kaufman, J., Bumstead, N., Lamont, S.J., Zhou, H.J., Hocking, P.M., Morrice, D., de Koning, D.J., Law, A., Bartley, N., Burt, D.W., Hunt, H., Cheng, H.H., Gunnarsson, U., Wahlberg, P., Andersson, L. et al. (2004) A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature, 432: 717–722.
   PubMed Web of Science ®Google Scholar
• Zhang, X., McDaniel, G.R., Roland, D.A. & Kuhlers, D.L. (1998) Responses to ten generations of divergent selection for tibial dyschondroplasia in broiler chickens: growth, egg production, and hatchability. Poultry Science, 77: 1065–1072.
   PubMed Web of Science ®Google Scholar