A novel 86-bp indel of the motilin receptor gene is significantly associated with growth and carcass traits in Gushi-Anka F₂ reciprocal cross chickens

References

• Amills, M., N. Jimenez, D. Villalba, M. Tor, E. Molina, D. Cubilo, C. Marcos, A. Francesch, A. Sanchez, and J. Estany. 2003. “Identification of Three Single Nucleotide Polymorphisms in the Chicken Insulin-like Growth Factor 1 and 2 Genes and Their Associations with Growth and Feeding Traits.” Poultry Science 82: 1485–1493. doi:10.1093/ps/82.10.1485.
   PubMed Web of Science ®Google Scholar
• Cui, Y., H. L. Yan, K. Wang, H. Xu, X. L. Zhang, H. J. Zhu, J. W. Liu, L. Qu, X. Y. Lan, and C. Y. Pan. 2018. “Insertion/Deletion within the KDM6A Gene Is Significantly Associated with Litter Size in Goat.” Frontiers in Genetics 9. doi:10.3389/fgene.2018.00173.
   Web of Science ®Google Scholar
• Dass, N. B., J. Hill, A. Muir, T. Testa, A. Wise, and G. J. Sanger. 2003. “The Rabbit Motilin Receptor: Molecular Characterisation and Pharmacology.” British Journal of Pharmacology 140: 948–954. doi:10.1038/sj.bjp.0705505.
   PubMed Web of Science ®Google Scholar
• Deloose, E., J. R. Biesiekierski, H. Vanheel, I. Depoortere, and J. Tack. 2018. “Effect of Motilin Receptor Activation on Food Intake and Food Timing.” American Journal of Clinical Nutrition 107: 537–543. doi:10.1093/ajcn/nqx044.
   PubMed Web of Science ®Google Scholar
• Deminm, A. G., I. Danilovas, and A. Galkina 2017. “The Analysis of the mtDNA D-loop Polymorphism for Assessing the Population Diversity of the Pavlov Chicken Breed.” Russian Journal of Genetics 7: 585–591. doi:10.1134/S2079059717060041.
   Google Scholar
• Feighner, S. D., C. P. Tan, K. K. Mckee, O. C. Palyha, D. L. Hreniuk, S. S. Pong, C. P. Austin, et al. 1999. “Receptor for Motilin Identified in the Human Gastrointestinal System.” Science 284: 2184–2188. doi:10.1126/science.284.5423.2184.
   PubMed Web of Science ®Google Scholar
• Han, R. L., Z. J. Li, M. J. Li, J. Q. Li, X. Y. Lan, G. R. Sun, X. T. Kang, and H. Chen. 2011. “Novel 9-bp Indel in Visfatin Gene and Its Associations with Chicken Growth.” British Poultry Science 52: 52–57. doi:10.1080/00071668.2010.537310.
   PubMed Web of Science ®Google Scholar
• Huang, Y. Z., J. J. Sun, L. Z. Zhang, C. J. Li, J. E. Womack, Z. J. Li, X. Y. Lan, et al. 2014. “Genome-wide DNA Methylation Profiles and Their Relationships with mRNA and the microRNA Transcriptome in Bovine Muscle Tissue (bos Taurine).” Scientific Reports 4: 1–17.
   Web of Science ®Google Scholar
• Huang, Y. Z., E. P. Zhang, H. Chen, J. Wang, Z. J. Li, Y. T. Huai, L. Ma, et al. 2010. “Novel 12-bp Deletion in the Coding Region of the Bovine NPM1 Gene Affects Growth Traits.” Journal of Applied Genetics 51: 199–202. doi:10.1007/BF03195728.
   PubMed Web of Science ®Google Scholar
• Kitazawa, T., A. Yoshida, T. Tamano, H. Teraoka, and H. Kaiya. 2013. “Age-dependent Reduction of Ghrelin- and Motilin-induced Contractile Activity in the Chicken Gastrointestinal Tract.” Peptides 43: 88–95. doi:10.1016/j.peptides.2013.02.012.
   PubMed Web of Science ®Google Scholar
• Li, W. Y., D. L. Liu, S. Q. Tang, D. H. Li, R. L. Han, Y. D. Tian, H. Li, et al. 2019. “A Multiallelic Indel in the Promoter Region of the Cyclin-dependent Kinase Inhibitor 3 Gene Is Significantly Associated with Body Weight and Carcass Traits in Chickens.” Poultry Science 98: 556–565. doi:10.3382/ps/pey404.
   PubMed Web of Science ®Google Scholar
• Li, Z. Q., Z. Zhang, Z. D. He, W. Tang, T. Li, Z. Zeng, L. He, and Y. Y. Shi. 2009. “A Partition-ligation-combination-subdivision EM Algorithm for Haplotype Inference with Multiallelic Markers: Update of the SHEsis.” Cell Research 19: 519–523. doi:10.1038/cr.2009.33.
   PubMed Web of Science ®Google Scholar
• Lins, T. C., R. G. Vieira, B. S. Abreu, P. Gentil, R. Moreno-Lima, R. J. Oliveira, and R. W. Pereira. 2011. “Genetic Heterogeneity of Self-reported Ancestry Groups in an Admixed Brazilian Population.” Journal of Epidemiology / Japan Epidemiological Association 21: 240–245. doi:10.2188/jea.je20100164.
   PubMed Web of Science ®Google Scholar
• Liu, F. 2009. “Conservation of Genetic Resources of Chinese Poultry.” Journal of Animal Science & Veterinary Medicine 21: 199–207.
   Google Scholar
• Lyu, S. J., Y. D. Tian, S. H. Wang, R. L. Han, X. X. Mei, and X. T. Kang. 2014. “A Novel 2-bp Indel within Krüppel-like Factor 15 Gene (\r, Klf15\r,) and Its Associations with Chicken Growth and Carcass Traits.” British Poultry Science 55: :427–434. doi:10.1080/00071668.2014.921886.
   PubMed Web of Science ®Google Scholar
• Merkin, J., C. Russell, P. Chen, and C. B. Burge. 2012. “Evolutionary Dynamics of Gene and Isoform Regulation in Mammalian Tissues.” Science 338: 1593–1599. doi:10.1126/science.1228186.
   PubMed Web of Science ®Google Scholar
• Nei, M., and A. K. Roychoudhury. 1974. “Sampling Variances of Heterozygosity and Genetic Distance.” Genetics 76: 379–390.
   PubMed Web of Science ®Google Scholar
• Nones, K., M. C. Ledur, D. C. Ruy, E. E. Baron, C. M. R. Melo, A. S. A. M. T. Moura, E. L. Zanella, D. W. Burt, and L. L. Coutinho. 2006. “Mapping QTLs on Chicken Chromosome 1 for Performance and Carcass Traits in a Broiler X Layer Cross.” Animal Genetics 37: 95–100. doi:10.1111/j.1365-2052.2005.01387.x.
   PubMed Web of Science ®Google Scholar
• Nunoi, H., B. Matsuura, S. Utsunomiya, T. Ueda, T. Miyake, S. Furukawa, T. Kumagi, et al. 2012. “A Relationship between Motilin and Growth Hormone Secretagogue Receptors.” Regulatory Peptides 176: 28–35. doi:10.1016/j.regpep.2012.03.001.
   PubMedGoogle Scholar
• Ohshiro, H., M. Nonaka, and K. Ichikawa. 2008. “Molecular Identification and Characterization of the Dog Motilin Receptor.” Regulatory Peptides 146: 80–87. doi:10.1016/j.regpep.2007.08.012.
   PubMedGoogle Scholar
• Piorkowska, K., J. Nowak, K. Poltowicz, and K. Ropka-Molik. 2014. “New Polymorphisms in Regulatory Region of Capn3 Gene with No Effect on Gene Expression in Breast Muscle of Broiler Chickens.” Annals of Animal Science 14: 511–524. doi:10.2478/aoas-2014-0032.
   Web of Science ®Google Scholar
• Ren, T., W. Li, D. Liu, K. Liang, X. Wang, H. Li, R. Jiang, Y. Tian, X. Kang, and Z. Li. 2019. “Two Insertion/deletion Variants in the Promoter Region of the QPCTL Gene are Significantly Associated with Body Weight and Carcass Traits in Chickens.” Animal Genetics 50: 279–282. doi:10.1111/age.12741.
   PubMed Web of Science ®Google Scholar
• Rosario, M. F., R. Gazaffi, A. S. A. M. T. Moura, M. C. Ledur, L. L. Coutinho, and A. A. F. Garcia. 2014. “Composite Interval Mapping and Mixed Models Reveal QTL Associated with Performance and Carcass Traits on Chicken Chromosomes 1, 3, and 4.” Journal of Applied Genetics 55: 97–103. doi:10.1007/s13353-013-0185-6.
   PubMed Web of Science ®Google Scholar
• Schmittgen, T. D., and K. J. Livak. 2008. “Analyzing Real-time Pcr Data by the Comparative Ct Method.” Nature Protocols 73: 1101–1110.
   PubMed Web of Science ®Google Scholar
• Takahashi, H., K. Rikimaru, M. Komatsu, Y. Uemoto, and K. Suzuki. 2014. “Association between Motilin Receptor Gene Haplotypes and Growth Traits in Japanese Hinai-dori Crossbred Chickens.” Asian-Australasian Journal of Animal Sciences 27: 316–323. doi:10.5713/ajas.2013.13500.
   PubMed Web of Science ®Google Scholar
• Tanaka, M., T. Miyazaki, I. Yamamoto, N. Nakai, Y. Ohta, N. Tsushima, M. Wakita, and K. Shimada. 2003. “Molecular Characterization of Chicken Growth Hormone Secretagogue Receptor Gene.” General and Comparative Endocrinology 134: 198–202.
   PubMed Web of Science ®Google Scholar
• Ter Beek, W. P., E. S. M. Muller, M. Van Den Berg, M. J. Meijer, I. Biemond, and C. B. H. W. Lamers. 2008. “Motilin Receptor Expression in Smooth Muscle, Myenteric Plexus, and Mucosa of Human Inflamed and Noninflamed Intestine.” Inflammatory Bowel Diseases 14: 612–619. doi:10.1002/ibd.20364.
   PubMed Web of Science ®Google Scholar
• Trudel, L., C. Tomasetto, M. C. Rio, M. Bouin, V. Plourde, P. Eberling, and P. Poitras. 2002. “Ghrelin/motilin-related Peptide Is a Potent Prokinetic to Reverse Gastric Postoperative Ileus in Rat.” American Journal of Physiology-Gastrointestinal and Liver Physiology 282: G948–G952. doi:10.1152/ajpgi.00339.2001.
   PubMed Web of Science ®Google Scholar
• Wang, W. H., J. Y. Wang, T. Zhang, Y. Wang, Y. Zhang, and K. Han. 2019. “Genome-wide Association Study of Growth Traits in Jinghai Yellow Chicken Hens Using SLAF-seq Technology.” Animal Genetics 50: 175–176. doi:10.1111/age.12346.
   PubMed Web of Science ®Google Scholar
• Wang, X. Y., Q. Yang, K. Wang, S. H. Zhang, C. Y. Pan, H. Chen, L. Qu, H. L. Yan, and X. Y. Lan. 2017. “A Novel 12-bp Indel Polymorphism within the GDF9 Gene Is Significantly Associated with Litter Size and Growth Traits in Goats.” Animal Genetics 48: 735–736. doi:10.1111/age.12617.
   PubMed Web of Science ®Google Scholar
• Xie, L., C. L. Luo, C. G. Zhang, R. Zhang, J. Tang, Q. H. Nie, L. Ma, et al. 2012. “Genome-Wide Association Study Identified a Narrow Chromosome 1 Region Associated with Chicken Growth Traits.” PloS One 7: e30910. doi:10.1371/journal.pone.0030910.
   Web of Science ®Google Scholar
• Yamamoto, I., H. Kaiya, C. Tsutsui, T. Sakai, A. Tsukada, M. Miyazato, and M. Tanakae. 2008. “Primary Structure, Tissue Distribution, and Biological Activity of Chicken Motilin Receptor.” General and Comparative Endocrinology 156: 509–514. doi:10.1016/j.ygcen.2008.03.007.
   PubMed Web of Science ®Google Scholar