90
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

An acute fatality and post-mortem concentration distribution reveals a low potential for naproxen redistribution

, &
Pages 203-210 | Received 04 Sep 2015, Accepted 12 Jan 2016, Published online: 10 Aug 2016

References

  • Moffat AC, Osselton MD, Widdop B (eds). Clarke's Analysis of Drugs and Poisons, 4th ed. London, UK: Pharmaceutical Press; 2011.
  • Baselt RC (ed). Disposition of Toxic Drugs and Chemicals in Man, 10th ed. Seal Beach, CA: Biomedical Publications; 2014.
  • Tomson G, Lunell NO, Oliw E. Relation of naproxen kinetics to effect on platelet prostaglandin release in men and dysmenorrheic women. Clin Pharmacol Ther. 1981;29:168–173.
  • Runkel RA, Forchielle E, Sevelius H, Chaplin M, Segre E. Nonlinear plasma level response to high doses of naproxen. Clin Pharmacol Ther. 1974;15:261–266.
  • Al-Abri SA, Anderson IB, Pedram F, Colby JM, Olson KR. Massive naproxen overdose with serial serum levels. J Med Toxicol. 2015;11:102–105.
  • Mullen WM, Meier KM, Hager SM, Olson KR. Severe naproxen overdose with elevated serum levels. Clin Toxicol. 2003;41:655.
  • Fredell EW, Strand LJ. Naproxen overdose [letter]. JAMA. 1977;238:938.
  • Drummer OH, Kotsos A, McIntyre IM. A class-independent drug screen in forensic toxicology using a photodiode array detector. J Anal Toxicol. 1993;17:225–229.
  • Hilberg T, Ripel A, Slordal L, Bjorneboe A, Morland J. The extent of postmortem drug redistribution in a rat model. J Forensic Sci. 1999;44:956–962.
  • Pounder DJ, Jones GR. Post-mortem drug redistribution - a toxicological nightmare. Forensic Sci Int. 1990;45:253–263.
  • Drummer OH. Postmortem toxicology of drugs of abuse. Forensic Sci Int. 2004;142:101–113.
  • Gerostamoulos D, Beyer J, Staikos V, Tayler P, Woodford N, Drummer OH. The effect of the postmortem interval on the redistribution of drugs: a comparison of mortuary admission and autopsy blood specimens. Forensic Sci Med Pathol. 2012;8:373–379.
  • Prouty RW, Anderson WH. The forensic science implications of site and temporal influences on postmortem blood-drug concentrations. J Forensic Sci. 1990;35:243–270.
  • Dalpe-Scott M, Degouffe M, Garbutt D, Drost M. A comparison of drug concentrations in postmortem cardiac and peripheral blood in 320 cases. Can Soc Forensic Sci J. 1995;28:113–121.
  • Leiken JB, Watson WA. Post-mortem toxicology: what the dead can and cannot tell us. Clin Tox. 2003;41:47–56.
  • Ferner RE. Post-mortem clinical toxicology. Br J Clin Pharm. 2008;66:430–443.
  • McIntyre IM, Sherrard J, Lucas J. Postmortem carisoprodol and meprobamate concentrations in blood and liver: lack of significant redistribution. J Anal Toxicol. 2012;36:177–181.
  • Cook J, Braithwaite RA, Hale KA. Estimating antemortem drug concentrations from postmortem blood samples: the influence of postmortem redistribution. J Clin Path. 2000;53:282–285.
  • Pélessier-Alicot AL, Gaulier JM, Champsaur P, Marquet P. Mechanisms underlying postmortem redistribution of drugs: a review. J Anal Toxicol. 2003;27:533–543.
  • McIntyre IM. Liver and peripheral blood concentration ratio (L/P) as a marker of postmortem drug redistribution: a literature review. Forensic Sci Med Pathol. 2014;10:91–96.
  • McIntyre IM, Meyer Escott C. Postmortem drug redistribution. J Forensic Res. 2012;3:e108. doi: 10.4172/2157-7145.1000e108
  • McIntyre IM, Anderson DT. Postmortem fentanyl concentrations: a review. J Forensic Res. 2012;3:8 157. doi: 10.4172/2157-7145.1000157
  • McIntyre IM, Mallett P, Trochta A, Morhaime J. Hydroxyzine distribution in postmortem cases and potential for redistribution. Forensic Sci Int. 2013;231:28–33.
  • McIntyre IM, Mallett P, Stabley R. Postmortem distribution of trazodone concentrations. Forensic Sci Int. 2015;251:195–201.
  • Nagasawa S, Daisuke Y, Suguru T, Fumiko C, Hirotaro I. Postmortem memantine concentration in a non-intoxication case, and the possibility of postmortem redistribution: a case report. Forensic Sci Int. 2015; doi: 10.1016/j.forsciint.2015.08.015
  • Heyland DK. Impaired gastric emptying in mechanically ventilated, critically ill patients. Intensive Care Medicine. 1996;22:1339–1344.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.