35
Views
5
CrossRef citations to date
0
Altmetric
Original

INVOLVEMENT OF P42/44 MAPK IN THE EFFECTS OF ETHANOL ON SECRETION OF INSULIN-LIKE GROWTH FACTOR (IGF)-I AND INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN (IGFBP)-1 IN PRIMARY CULTURED RAT HEPATOCYTES

, , , , , & show all
Pages 187-201 | Received 01 Dec 2005, Published online: 07 Jul 2009

REFERENCES

  • Aroor A. R., Shukla S. D. MAP kinase signaling in diverse effects of ethanol. Life Science 2004; 74(19)2339–2364
  • Brismar K., Grill V., Efendic S., Hall K. The insulin-like growth factor binding protein-1 in low and high insulin responders before and during dexamethasone treatment. Metabolism 1991; 40(7)728–732
  • Chen J., Ishac E. J., Dent P., Kunos G., Gao B. Effects of ethanol on mitogen-activated protein kinase and stress-activated protein kinase cascades in normal and regenerating liver. Biochemical Journal 1998; 334(Pt 3)669–676
  • Crabb D. W., Bosron W. F., Li T. K. Ethanol metabolism. Pharmacology & Therapeutics 1987; 34(1)59–73
  • Cross T. G., Scheel-Toellner D., Henriquez N. V., Deacon E., Salmon M., Lord J. M. Serine/threonine protein kinases and apoptosis. Experimental Cell Research 2000; 256(1)34–41
  • Hoek J. B., Pastorino J. G. Ethanol, oxidative stress, and cytokine-induced liver cell injury. Alcohol 2002; 27(1)63–68
  • Jones J. I., Clemmons D. R. Insulin-like growth factors and their binding proteins: Biological actions. Endocrine Reviews 1995; 16(1)3–34
  • Knip M., Ekman A. C., Ekman M., Leppaluoto J., Vakkuri O. Ethanol induces a paradoxical simultaneous increase in circulating concentrations of insulin-like growth factor binding protein-1 and insulin. Metabolism 1995; 44(10)1356–1359
  • Kurose I., Higuchi H., Miura S., Saito H., Watanabe N., Hokari R., Hirokawa M., Takaishi M., Zeki S., Nakamura T., Ebinuma H., Kato S., Ishii H. Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication. Hepatology 1997; 25(2)368–378
  • Lee C. Y., Henricks D. M. Comparisons of various acidic treatments of bovine serum on insulin-like growth factor-I immunoreactivity and binding activity. Journal of Endocrinology 1990; 127: 139–148
  • Lee M. S., Kang C. W., Ryu H., Kim J. D., Chung H. T. Effects of ChunDoSunBup Qi-training on growth hormone, insulin-like growth factor-I, and testosterone in young and elderly subjects. American Journal of Chinese Medicine 1999; 27: 167–175
  • Lee S. M., Kang C. W. Effects of ethanol on secretion of insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-1 (IGBP-1) in primary rat hepatocytes: Involvement of lipid peroxidase (LPO) activity. Korean Journal of Laboratory and Animal Science 2004; 20(4)391–397
  • Lee Y. J., Aroor A. R., Shukla S. D. Temporal activation of p42/44 mitogen-activated protein kinase and c-Jun N-terminal kinase by acetaldehyde in rat hepatocytes and its loss after chronic ethanol exposure. Journal of Pharmacology and Experimental Therapeutics 2002; 301(3)908–914
  • Lee Y. J., Shukla S. D. Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes. European Journal of Pharmacology 2005; 508: 31–45
  • Lieber C. S. Mechanism of ethanol induced hepatic injury. Pharmacology & Therapeutics 1990; 46(1)1–41
  • Lieber C. S. Hepatic, metabolic, and nutritional disorders of alcoholism: From pathogenesis to therapy. Critical Reviews in Clinical Laboratory Sciences 2000; 37(6)551–584
  • Nomura F., Pikkarainen P. H., Jauhonen P., Arai M., Gordon E. R., Baraona E., Lieber C. S. Effect of ethanol administration on the metabolism of ethanol in baboons. Journal of Pharmacology and Experimental Therapeutics 1983; 227(1)78–83
  • Park S. H., Heo J. S., Kang C. W. Dose-dependent effect of alcohol on insulin-like growth factor systems in male rats. Clin. Exp. Pharmacol. Physiol. 2004; 31: 22–28
  • Perks C. M., Newcomb P. V., Norman M. R., Holly J. M. Effect of insulin-like growth factor binding protein-1 on integrin signalling and the induction of apoptosis in human breast cancer cells. Journal of Molecular Endocrinology 1999; 22(2)141–150
  • Reddy M. A., Shukla S. D. Potentiation of mitogen-activated protein kinase by ethanol in embryonic liver cells. Biochemical Pharmacology 1996; 51(5)661–668
  • Rojdmark S., Brismar K. Decreased IGF-I bioavailability after ethanol abuse in alcoholics: Partial restitution after short-term abstinence. Journal of Endocrinological Investigation 2001; 24(7)476–482
  • Rojdmark S., Rydvald Y., Aquilonius A., Brismar K. Insulin-like growth factor (IGF)-1 and IGF-binding protein-1 concentrations in serum of normal subjects after alcohol ingestion: Evidence for decreased IGF-1 bioavailability. Clinical Endocrinology 2000; 52(3)313–318
  • Schwander J. C., Hauri C., Zapf J., Froesch E. R. Synthesis and secretion of insulin-like growth factor and its binding protein by the perfused rat liver: Dependence on growth hormone status. Endocrinology 1983; 113(1)297–305
  • Seglen P. O. Preparation of isolated rat liver cells. Methods in Cell Biology 1976; 13: 29–83
  • Shukla S. D., Sun G., Wood W. C., Savolainem M. J., Alling C., Hoek J. B. Ethanol and lipid metabolic signaling. Alcoholism, Clinical and Experimental Research 2001; 24: 33S–39S
  • Su B., Karin M. Mitogen-activated protein kinase cascades and regulation of gene expression. Current Opinion in Immunology 1996; 8(3)402–411
  • Tampier L., Mardones J. Effect of 3-amino-1,2,4-triazole pretreatment on ethanol blood levels after intraperitoneal administration. Alcohol 1986; 3(3)181–183
  • Tombes R. M., Auer K. L., Mikkelsen R., Valerie K., Wymann M. P., Marshall C. J., McMahon M., Dent P. The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic. Biochemical Journal 1998; 330(Pt 3)1451–1460
  • Weng Y., Shukla S. D. Ethanol alters angiotensin II stimulated mitogen activated protein kinase in hepatocytes: Agonist selectivity and ethanol metabolic independence. European Journal of Pharmacology 2000; 398(3)323–331

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.