321
Views
23
CrossRef citations to date
0
Altmetric
Original

Does Neurotropin-3 Have a Therapeutic Implication in Major Depression?

, , , &
Pages 1515-1522 | Received 01 Jan 2008, Published online: 07 Jul 2009

REFERENCES

  • Bothwell M. Functional interactions of neurotrophins and neurotrophin receptors. Annual Review of Neuroscience 1995; 18: 223–253
  • Bourin M., David D. J., Jolliet P., Gardier A. Mechanism of action of antidepressants and therapeutic perspectives. Therapie 2002; 57(4)385–396
  • Cavanaugh J. E., Ham J., Hetman M., Poser S., Yan C., Xia Z. Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons. Journal of Neuroscience 2001; 21(2)434–443
  • Celada P., Siuciak J. A., Tran T. M., Altar C. A., Tepper J. M. Local infusion of brain-derived neurotrophic factor modifies the firing pattern of dorsal raphe serotonergic neurons. Brain Research 1996; 712(2)293–298
  • Crown W. H., Finkelstein S., Berndt E. R., Ling D., Poret A. W., Rush A. J., et al. The impact of treatment-resistant depression on health care utilization and costs. The Journal of Clinical Psychiatry 2002; 63(11)963–971
  • Duman R. S. Pathophysiology of depression: The concept of synaptic plasticity. Euopeanr Psychiatry 2002; 17(Suppl. 3)S306–S310
  • Faure J., Uys J. D., Marais L., Stein D. J., Daniels W. M. Early maternal separation followed by later stressors leads to dysregulation of the HPA-axis and increases in hippocampal NGF and NT-3 levels in a rat model. Metabolic Brain Disease 2006; 21(2–3)181–188
  • Fava M., Thase M. E., DeBattista C. A multicenter, placebo-controlled study of modafinil augmentation in partial responders to selective serotonin reuptake inhibitors with persistent fatigue and sleepiness. The Journal of Clinical Psychiatry 2005; 66(1)85–93
  • Freeman A. Y., Pierce R. C. Neutralization of neutrophin-3 in the ventral tegmental area or nucleus accumbens differentially modulates cocaine-induced behavioral plasticity in rats. Synapse 2002; 46(2)57–65
  • Fumagalli F., Molteni R., Calabrese F., Frasca A., Racagni G., Riva M. A. Chronic fluoxetine administration inhibits extracellular signal-regulated kinase 1/2 phosphorylation in rat brain. Journal of Neurochemistry 2005; 93(6)1551–1560
  • Gratacos M., Soria V., Urretavizcaya M., Gonzalez J. R., Crespo J. M., Bayes M., et al. A brain-derived neurotrophic factor (BDNF) haplotype is associated with antidepressant treatment outcome in mood disorders. Pharmacogenomics Journal 2007; 8(2)101–112
  • Hoshaw B. A., Malberg J. E., Lucki I. Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects. Brain Research 2005; 1037(1–2)204–208
  • Huang T. L., Lee C. T., Liu Y. L. Serum brain-derived neurotrophic factor levels in patients with major depression: Effects of antidepressants. Journal of Psychiatric Research 2008; 42(7)521–525
  • Kempermann G., Kronenberg G. Depressed new neurons—Adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression. Biological Psychiatry 2003; 54(5)499–503
  • Kushikata T., Kubota T., Fang J., Krueger J. M. Neurotrophins 3 and 4 enhance non-rapid eye movement sleep in rabbits. Neuroscience Letters 2003; 346(3)161–164
  • Mamounas L. A., Blue M. E., Siuciak J. A., Altar C. A. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain. Journal of Neuroscience 1995; 15(12)7929–7939
  • Martin-Iverson M. T., Todd K. G., Altar C. A. Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: Interactions with amphetamine. Journal of Neuroscience 1994; 14(3 Pt. 1)1262–1270
  • Nielsen D. M. Corticotropin-releasing factor type-1 receptor antagonists: the next class of antidepressants?. Life Sciences 2006; 78(9)909–919
  • Paul J., Gottmann K., Lessmann V. NT-3 regulates BDNF-induced modulation of synaptic transmission in cultured hippocampal neurons. Neuroreport 2001; 12(12)2635–2639
  • Pierce R. C., Pierce-Bancroft A. F., Prasad B. M. Neurotrophin-3 contributes to the initiation of behavioral sensitization to cocaine by activating the Ras/Mitogen-activated protein kinase signal transduction cascade. Journal of Neuroscience 1999; 19(19)8685–8695
  • Saarelainen T., Hendolin P., Lucas G., Koponen E., Sairanen M., MacDonald E., et al. Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects. Journal of Neuroscience 2003; 23(1)349–357
  • Sandi C., Bisaz R. A model for the involvement of neural cell adhesion molecules in stress-related mood disorders. Neuroendocrinology 2007; 85(3)158–176
  • Schutte A., Yan Q., Mestres P., Giehl K. M. The endogenous survival promotion of axotomized rat corticospinal neurons by brain-derived neurotrophic factor is mediated via paracrine, rather than autocrine mechanisms. Neuroscience Letters 2000; 290(3)185–188
  • Sheline Y. I., Wang P. W., Gado M. H., Csernansky J. G., Vannier M. W. Hippocampal atrophy in recurrent major depression. Proceedings of the National Academy of Sciences of the United States of America 1996; 93(9)3908–3913
  • Shimazu K., Zhao M., Sakata K., Akbarian S., Bates B., Jaenisch R., et al. NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis. Learning & Memory 2006; 13(3)307–315
  • Sieber-Blum M., Ren Z. Norepinephrine transporter expression and function in noradrenergic cell differentiation. Molecular and Cellular Biochemistry 2000; 212(1–2)61–70
  • Siuciak J. A., Boylan C., Fritsche M., Altar C. A., Lindsay R. M. BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration. Brain Research 1996; 710(1–2)11–20
  • Smith M. A., Makino S., Altemus M., Michelson D., Hong S. K., Kvetnansky R., et al. Stress and antidepressants differentially regulate neurotrophin 3 mRNA expression in the locus coeruleus. Proceedings of the National Academy of Sciences of the United States of America 1995; 92(19)8788–8792
  • Tardito D., Perez J., Tiraboschi E., Musazzi L., Racagni G., Popoli M. Signaling pathways regulating gene expression, neuroplasticity, and neurotrophic mechanisms in the action of antidepressants: a critical overview. Pharmacological Reviews 2006; 58(1)115–134
  • Walz J. C., Frey B. N., Andreazza A. C., Cereser K. M., Cacilhas A. A., Valvassori S. S., et al. Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania. Journal of Psychiatric Research, in press

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.