Curcumin and resveratrol rescue cortical–hippocampal system from chronic fluoride-induced neurodegeneration and enhance memory retrieval

References

• Stern CE, Sherman SJ, Kirchhoff BA, et al. Medial temporal and prefrontal contributions to working memory tasks with novel and familiar stimuli. Hippocampus. 2001 Jan;11(4):337–346.
   PubMed Web of Science ®Google Scholar
• Bhatnagar M, Rao P, Jain S, et al. Neurotoxicity of fluoride: neurodegeneration in hippocampus of female mice. 2002 May;40(4):546–554.
   Google Scholar
• Bhatnagar M, Rao P, Saxena A, et al. Biochemical changes in brain and other tissues of young adult female mice from fluoride in their drinking water. Fluoride. 2006 Dec;39(4):280–284.
   Web of Science ®Google Scholar
• Chirumari K, Reddy PK. Dose-dependent effects of fluoride on neurochemical milieu in the hippocampus and neocortex of rat brain. Fluoride. 2007 Jun;40(2):101–110.
   Web of Science ®Google Scholar
• Basha PM, Rai P, Begum S. Evaluation of fluoride-induced oxidative stress in rat brain: a multigeneration study. Biol Trace Elem Res. 2011 Sep;142(3):623–637.
   PubMed Web of Science ®Google Scholar
• Bhatnagar M, Sukhwal P, Suhalka P, et al. Effects of fluoride in drinking water on NADPH-diaphorase neurons in the forebrain of mice: a possible mechanism of fluoride neurotoxicity. Fluoride. 2011 Oct;44(4):195–209.
   Web of Science ®Google Scholar
• Blaylock RL. Excitotoxicity: a possible central mechanism in fluoride neurotoxicity. Fluoride. 2004 Nov;37(4):301–314.
   Web of Science ®Google Scholar
• Zhang M, Wang A, Xia T, et al. Effects of fluoride on DNA damage, S-phase cell-cycle arrest and the expression of NF-κB in primary cultured rat hippocampal neurons. Toxicol Lett. 2008 Jun;179(1):1–5.
   PubMed Web of Science ®Google Scholar
• Virgili M, Contestabile A. Partial neuroprotection of in vivo excitotoxic brain damage by chronic administration of the red wine antioxidant agent, trans-resveratrol in rats. Neurosci Lett. 2000 Mar;281(2):123–126.
   PubMed Web of Science ®Google Scholar
• Kovacsova M, Barta A, Parohova J, et al. Neuroprotective mechanisms of natural polyphenolic compounds. Activitas Nervosa Superior Rediviva. 2010;52(3):181–186.
   Google Scholar
• Ak T, Gülçin İ. Antioxidant and radical scavenging properties of curcumin. Chem Biol Interact. 2008 Jul;174(1):27–37.
   PubMed Web of Science ®Google Scholar
• Tiwari SK, Agarwal S, Tripathi A, et al. Bisphenol-A mediated inhibition of hippocampal neurogenesis attenuated by curcumin via canonical Wnt pathway. Mol Neurobiol. 2016 Jul;53(5):3010–3029.
   PubMed Web of Science ®Google Scholar
• Frémont L. Biological effects of resveratrol. Life Sci. 2000 Jan;66(8):663–673.
   PubMed Web of Science ®Google Scholar
• Orallo F. Comparative studies of the antioxidant effects of cis- and trans-resveratrol. Curr Med Chem. 2006 Jan;13(1):87–98.
   PubMed Web of Science ®Google Scholar
• Yazir Y, Utkan T, Gacar N, et al. Resveratrol exerts anti-inflammatory and neuroprotective effects to prevent memory deficits in rats exposed to chronic unpredictable mild stress. Physiol Behav. 2015 Jan;138:297–304.
   PubMed Web of Science ®Google Scholar
• Hope BT, Vincent SR. Histochemical characterization of neuronal NADPH-diaphorase. J Histochem Cytochem. 1989 May;37(5):653–661.
   PubMed Web of Science ®Google Scholar
• Keith BJ, Franklin GP, Paxinos G. The mouse brain in stereotaxic coordinates. 3rd ed. Amsterdam: Elsevier Science Publishing Co Inc; 2008. p. 256.
   Google Scholar
• Weissman BA, Gross SS. Measurement of NO and NO synthase. Current Protocols Neurosci. 2001 May;7–13. Available from: https://doi.org/10.1002/0471142301.ns0713s05
   Google Scholar
• Mattson MP, Zhang Y, Bose S. Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis, and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose. Exp Neurol. 1993 May;121(1):1–3.
   PubMed Web of Science ®Google Scholar
• Mattson MP, Chan SL. Dysregulation of cellular calcium homeostasis in Alzheimer's disease. J Mol Neurosci. 2001;17.2:205–224.
   Web of Science ®Google Scholar
• Utley HG, Bernheim F, Hochstein P. Effect of sulfhydryl reagents on peroxidation in microsomes. Arch Biochem Biophys. 1967 Jan;118(1):29–32.
   Web of Science ®Google Scholar
• Myhre O, Andersen JM, Aarnes H, et al. Evaluation of the probes 2′, 7′-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation. Biochem Pharmacol. 2003 May;65(10):1575–1582.
   PubMed Web of Science ®Google Scholar
• Hissin PJ, Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem. 1976 Jul;74(1):214–226.
   PubMed Web of Science ®Google Scholar
• Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods. 1984 May;11(1):47–60.
   PubMed Web of Science ®Google Scholar
• Ettinger RH, Staddon JE. Operant regulation of feeding: a static analysis. Behav Neurosci. 1983 Aug;97(4):639.
   PubMed Web of Science ®Google Scholar
• Thomas E, Pearse AG. The fine localization of dehydrogenases in the nervous system. Histochem Cell Biol. 1961 Jul;2(4):266–282.
   Web of Science ®Google Scholar
• Beesley JE. Histochemical methods for detecting nitric oxide synthase. Histochem J. 1995 Oct;27(10):757–769.
   PubMedGoogle Scholar
• Giraldi-Guimarães A, Tenório F, Brüning G, et al. Nitric oxide synthase expression in the opossum superior colliculus: a histochemical, immunohistochemical and biochemical study. Brain Behav Evol. 1999;54(6):303–313.
   PubMed Web of Science ®Google Scholar
• Snyder SH, Bredt DS. Nitric oxide as a neuronal messenger. Trends Pharmacol Sci. 1991 Jan;12:125–128.
   PubMed Web of Science ®Google Scholar
• Xu S, Shu B, Chen Z. Effects of fluoride on activities of nitric oxide synthase in rat brain. Fluoride. 2001;34(1):84.
   Google Scholar
• Ritz MF, Curin Y, Mendelowitsch A, et al. Acute treatment with red wine polyphenols protects from ischemia-induced excitotoxicity, energy failure and oxidative stress in rats. Brain Res. 2008 Nov;1239:226–234.
   PubMed Web of Science ®Google Scholar
• Prast H, Philippu A. Nitric oxide as modulator of neuronal function. Prog Neurobiol. 2001 May;64(1):51–68.
   PubMed Web of Science ®Google Scholar
• Leveille F, Gouix E, Lecocq M, et al. Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors. FASEB J. 2008 Dec;22(12):4258–4271.
   PubMed Web of Science ®Google Scholar
• Wei T, Chen C, Hou J, et al. Nitric oxide induces oxidative stress and apoptosis in neuronal cells. Biochimica et Biophysica Acta (BBA) – Mol Cell Res. 2000 Oct;1498(1):72–79.
   PubMed Web of Science ®Google Scholar
• Fulda S, Gorman AM, Hori O, et al. Cellular stress responses: cell survival and cell death. Int J Cell Biol. 2010;2010:214074. doi:10.1155/2010/214074
   PubMedGoogle Scholar
• Gaweł S, Wardas M, Niedworok E, et al. Malondialdehyde (MDA) as a lipid peroxidation marker. Wiad Lek. 2003 Dec;57(9–10):453–455.
   Google Scholar
• Ghoneim AI, Abdel-Naim AB, Khalifa AE, et al. Protective effects of curcumin against ischaemia/reperfusion insult in rat forebrain. Pharmacol Res. 2002 Sep;46(3):273–279.
   PubMed Web of Science ®Google Scholar
• Sharma C, Suhalka P, Sukhwal P, et al. Curcumin attenuates neurotoxicity induced by fluoride: an in vivo evidence. Pharmacogn Mag. 2014 Jan-Mar;10(37):61–65.
   PubMed Web of Science ®Google Scholar
• Butterfield DA, Castegna A, Pocernich CB, et al. Nutritional approaches to combat oxidative stress in Alzheimer's disease. J Nutr Biochem. 2002 Aug;13(8):444–461.
   PubMed Web of Science ®Google Scholar
• Lopez MS, Dempsey RJ, Vemuganti R. Resveratrol neuroprotection in stroke and traumatic CNS injury. Neurochem Int. 2015 Oct;89:75–82.
   PubMed Web of Science ®Google Scholar
• Madhusudhan N, Basha PM, Rai P, et al. Effect of maternal fluoride exposure on developing CNS of rats: protective role of aloe vera, curcuma longa and ocimum sanctum. Indian J Exp Biol. 2010 Aug;48(8):830–836
   PubMed Web of Science ®Google Scholar
• Kim SJ, Son TG, Park HR, et al. Curcumin stimulates proliferation of embryonic neural progenitor cells and neurogenesis in the adult hippocampus. J Biol Chem. 2008 May;283(21):14497–14505.
   PubMed Web of Science ®Google Scholar
• Vorhees CV, Williams MT. Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nat Protoc. 2006 Aug;1(2):848–858.
   PubMed Web of Science ®Google Scholar
• Schmatz R, Mazzanti CM, Spanevello R, et al. Resveratrol prevents memory deficits and the increase in acetylcholinesterase activity in streptozotocin-induced diabetic rats. Eur J Pharmacol. 2009 May;610(1):42–48.
   PubMed Web of Science ®Google Scholar
• Pan R, Qiu S, Lu DX, et al. Curcumin improves learning and memory ability and its neuroprotective mechanism in mice. Chin Med J (Engl). 2008 May 5;121(9):832–839.
   PubMed Web of Science ®Google Scholar