Advanced search
Publication Cover
International Journal of Neuroscience Volume 130, 2020 - Issue 6
Submit an article Journal homepage
127
Views
6
CrossRef citations to date
0
Altmetric
Original Articles

The effects of minocycline on proliferation, differentiation and migration of neural stem/progenitor cells

Fatemeh ShamsiDepartment of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; ;Neuroscience Laboratory (Brain, Cognition and Behavior), Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; View further author information
,
Zahra ZeraatpishehDepartment of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; ;Neuroscience Laboratory (Brain, Cognition and Behavior), Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; View further author information
,
Hamed AlipourDepartment of Tissue Engineering & Applied Cell Sciences, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; View further author information
,
Abbas NazariDepartment of Biology, Shiraz Branch, Islamic Azad University, Shiraz, IranView further author information
&
Hadi AligholiDepartment of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; ;Neuroscience Laboratory (Brain, Cognition and Behavior), Department of Neuroscience, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran; Correspondence[email protected]
View further author information
Pages 601-609 | Received 28 Jul 2019, Accepted 21 Nov 2019, Published online: 05 Dec 2019

References

  • Kim SU, Lee HJ, Kim YB. Neural stem cell‐based treatment for neurodegenerative diseases. Neuropathology. 2013;33:491–504.
  • Rueger MA, Muesken S, Walberer M, et al. Effects of minocycline on endogenous neural stem cells after experimental stroke. Neuroscience. 2012;215:174–183.
  • Yong VW, Wells J, Giuliani F, et al. The promise of minocycline in neurology. Lancet Neurol. 2004;3(12):744–751.
  • Garrido-Mesa N, Zarzuelo A, Gálvez J. Minocycline: far beyond an antibiotic. Br J Pharmacol. 2013;169(2):337–352.
  • Yrjanheikki J, Keinanen R, Pellikka M, et al. Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia. Proc Natl Acad Sci U S A. 1998;95(26):15769–15774.
  • Yrjanheikki J, Tikka T, Keinanen R, et al. A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window. Proc Natl Acad Sci U S A. 1999;96(23):13496–13500.
  • Lampl Y, Boaz M, Gilad R, et al. Minocycline treatment in acute stroke: an open-label, evaluator-blinded study. Neurology. 2007;69(14):1404–1410.
  • Zhang Y, Metz LM, Yong VW, et al. Pilot study of minocycline in relapsing-remitting multiple sclerosis. Can J Neurol Sci. 2008;35(2):185–191.
  • Wells J, Hurlbert J, Fehlings M, et al. Neuroprotection by minocyclin facilitates significant recovery from spinal cord injury in mice. Brain. 2003;126(7):1628–1637.
  • Plane JM, Shen Y, Pleasure DE, et al. Prospects for minocycline neuroprotection. Arch Neurol. 2010;67(12):1442–1448.
  • Jantzen SU, Müsken S, Schroeter MW, et al. Effects of inflammatory cytokines and minocycline on cultured neural stem cells. Klin Neurophysiol. 2012;43(01):V091.
  • Lu Y, Giri PK, Lei S, et al. Pretreatment with minocycline restores neurogenesis in the subventricular zone and subgranular zone of the hippocampus after ketamine exposure in neonatal rats. Neuroscience. 2017;352:144–154.
  • Gage FH. Mammalian neural stem cells. Science. 2000;287(5457):1433–1438.
  • Aligholi H, Hassanzadeh G, Azari H, et al. A new and safe method for stereotactically harvesting neural stem/progenitor cells from the adult rat subventricular zone. J Neurosci Methods. 2014;225:81–89.
  • Einstein O, Ben-Hur T. The changing face of neural stem cell therapy in neurologic diseases. Arch Neurol. 2008;65(4):452–456.
  • Aligholi H, Rezayat SM, Azari H, et al. Preparing neural stem/progenitor cells in PuraMatrix hydrogel for transplantation after brain injury in rats: a comparative methodological study. Brain Res. 2016;1642:197–208.
  • Negah SS, Khaksar Z, Aligholi H, et al. Enhancement of neural stem cell survival, proliferation, migration, and differentiation in a novel self-assembly peptide nanofibber scaffold. Mol Neurobiol. 2017;54:8050–8062.
  • Lee SM, Yune TY, Kim SJ, Park DW, et al. Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat. J Neurotrauma. 2003;20(10):1017–1027.
  • Sakata H, Niizuma K, Yoshioka H, et al. Minocycline-preconditioned neural stem cells enhance neuroprotection after ischemic stroke in rats. J Neurosci. 2012;32(10):3462–3473.
  • Vay SU, Blaschke S, Klein R, et al. Minocycline mitigates the gliogenic effects of proinflammatory cytokines on neural stem cells. J Neurosci Res. 2016;94(2):149–160.
  • Burdick JA, Vunjak-Novakovic G. Engineered microenvironments for controlled stem cell differentiation. Tissue Eng Part A. 2009;15(2):205–219.
  • Zhang S, Zhao X, Spirio L. PuraMatrix: self-assembling peptide nanofiber scaffolds. In: Ma PX, Elisseeff J, editors. Scaffolding in tissue engineering. 2005. p. 217–238.
  • Imitola J, Raddassi K, Park KI, et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway. Proc Natl Acad Sci. 2004;101(52):18117–18122.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.