182
Views
7
CrossRef citations to date
0
Altmetric
Original Articles

Association between methylene tetrahydrofolate reductase polymorphisms and risk of ischemic stroke

, , , , , , & show all
Pages 44-48 | Received 28 Dec 2018, Accepted 11 Feb 2020, Published online: 26 Feb 2020

References

  • Francis J, Raghunathan S, Khanna P. The role of genetics in stroke. Postgrad Med J. 2007;83(983):590–595.
  • Azarpazhooh MR, Etemadi MM, Donnan GA, et al. Excessive incidence of stroke in Iran: evidence from the Mashhad Stroke Incidence Study (MSIS), a population-based study of stroke in the Middle East. Stroke. 2010;41(1):e3–e10.
  • Perry IJ, Refsum H, Morris RW, et al. Prospective study of serum total homocysteine concentration and risk of stroke in middle-aged British men. Lancet 1995;346(8987):1395–1398.
  • Shahzad K, Hai A, Ahmed A, et al. A structured-based model for the decreased activity of Ala222Val and Glu429Ala methylenetetrahydrofolate reductase (MTHFR) mutants. Bioinformation. 2013;9(18):929–936.
  • Kim YI, Role of the MTHFR polymorphisms in cancer risk modification and treatment. Future Oncol. 2009;5(4):523–542.
  • Jafarian N, Sheikhha MH, Samadani AA, MTHFR gene at rs A1298C polymorphism in type II diabetes among Iranian population. Electron J Gen Med. 2018;15(4).
  • Yang BY, Fan SJ, Zhi XY, Li YF, et al. Associations of MTHFR gene polymorphisms with hypertension and hypertension in pregnancy: a meta-analysis from 114 studies with 15411 cases and 21970 controls. Plos One. 2014;9(2).
  • Zhou BS, Bu GY, Li M, et al. Tagging SNPs in the MTHFR gene and risk of ischemic stroke in a Chinese population. Int J Mol Sci. 2014;15(5):8931–8940.
  • McIlroy SP, Dynan KB, Lawson JT, et al. Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland. Stroke. 2002;33(10):2351–2356.
  • Rutten-Jacobs LCA, Traylor M, Adib-Samii P, et al. Association of MTHFR C677T genotype with ischemic stroke is confined to cerebral small vessel disease subtype. Stroke. 2016;47(3):646–651.
  • Naghibalhossaini F, Mokarram P, Khalili I, et al. MTHFR C677T and A1298C variant genotypes and the risk of microsatellite instability among Iranian colorectal cancer patients. Cancer Genet Cytogen. 2010;197(2):142–151.
  • Naghibalhossaini F, Ehyakonandeh H, Nikseresht A, et al. Association between MTHFR genetic variants and multiple sclerosis in a southern Iranian population. Int J Mol Cell Med. 2015;4(2):87–93.
  • Attar M, Shirangi S, Shateri F, et al. Common variant of 5, 10-methylenetetrahydrofolate reductase may increase risk of coronary artery disease in the Iranian population. Egypt J Med Hum Genet.. 2018;19(1):1–5.
  • Solé X, Guinó E, Valls J, et al. SNPStats: a web tool for the analysis of association studies. Bioinformatics. 2006;22(15):1928–1929.
  • Frosst P, Blom HJ, Milos R, Goyette P, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet. 1995;10(1):111–113.
  • Zhao X, Jiang H, Quantitative assessment of the association between MTHFR C677T polymorphism and hemorrhagic stroke risk. Mol Biol Rep. 2013;40(1):573–578.
  • Hamzi K, Tazzite A, Nadifi S, Large-scale meta-analysis of genetic studies in ischemic stroke: five genes involving 152,797 individuals. Indian J Hum Genet. 2011;17(3):212–217.
  • Chen M, Mao BY, Wang D, et al. Association between rs1801133 polymorphism and risk of adult ischemic stroke: meta-analysis based on case-control studies. Thromb Res. 2016;137:17–25.
  • Hariri M, Maghsoudi Z, Darvishi L, et al. B vitamins and antioxidants intake is negatively correlated with risk of stroke in Iran. Int J Prev Med. 2013;4(Suppl 2):S284–S289.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.