MiRNA: a potential target for gene diagnosis and treatment of atherosclerotic stroke

References

• Lee YS, Nakahara K, Pham JW, et al. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell. 2004;117(1):69–81.
   PubMed Web of Science ®Google Scholar
• Eulalio A, Huntzinger E, Izaurralde E. Getting to the root of miRNA-Mediated gene silencing. Cell. 2008;132(1):9–14.
   PubMed Web of Science ®Google Scholar
• Chi SW, Zang JB, Mele A, et al. Ago HITS-CLIP decodes miRNA-mRNA interaction maps. Nature. 2009;460(7254):479–486.
   PubMed Web of Science ®Google Scholar
• Wong KS, Li H. Long-term mortality and recurrent stroke risk among Chinese stroke patients with predominant intracranial atherosclerosis. Stroke. 2003;34(10):2361–2366.
   PubMed Web of Science ®Google Scholar
• Elkind MS. Inflammation, atherosclerosis, and stroke. Neurologist. 2006;12(3):140–148.
   PubMed Web of Science ®Google Scholar
• Feigin VL, Roth GA, Naghavi M, et al. Global burden of stroke and risk factors in 188 countries, during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet Neurol. 2016;15(9):913–924.
   PubMed Web of Science ®Google Scholar
• Hja VO, Mulder IA, Broersen A, et al. Migraine and cerebrovascular atherosclerosis in patients with ischemic stroke. Stroke. 2017;48(7):1973–1975.
   PubMed Web of Science ®Google Scholar
• Helwak A, Kudla G, Dudnakova T, et al. Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding. Cell. 2013;153(3):654–665.
   PubMed Web of Science ®Google Scholar
• Ventura A, Young AG, Winslow MM, et al. Targeted deletion reveals essential and overlapping functions of the miRNA-17 ∼ 92 family of miRNA clusters. Cell. 2008;132(5):875–886.
   PubMed Web of Science ®Google Scholar
• Zhao Y, Ransom JF, Li A, et al. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell. 2007;129(2):303–317.
   PubMed Web of Science ®Google Scholar
• Feinberg MW, Moore KJ. MiRNA regulation of atherosclerosis. Circ Res. 2016;118(4):703–720.
   PubMed Web of Science ®Google Scholar
• Nazari-Jahantigh M, Egea V, Schober A, et al. miRNA-specific regulatory mechanisms in atherosclerosis. J Mol Cell Cardiol. 2015;89(Pt A):35–41.
   PubMed Web of Science ®Google Scholar
• Soh J, Iqbal J, Queiroz J, et al. MiRNA-30c reduces hyperlipidemia and atherosclerosis in mice by decreasing lipid synthesis and lipoprotein secretion. Nat Med. 2013;19(7):892–900.
   PubMed Web of Science ®Google Scholar
• Rotllan N, Ramírez CM, Aryal B, et al. Therapeutic silencing of microRNA-33 inhibits the progression of atherosclerosis in Ldlr−/− mice. Arterioscler Thromb Vasc Biol. 2013;33(8):1973–1977.
   PubMed Web of Science ®Google Scholar
• Takahiro H, Osamu B, Yasuhide K, et al. MiRNA-33 deficiency reduces the progression of atherosclerotic plaque in ApoE−/−Mice. J Am Heart Assoc Cardiovasc Cerebrovasc Dis. 2012;1(6):e003376.
   PubMed Web of Science ®Google Scholar
• Schober A, Nazari-Jahantigh M, Weber C. MiRNA-mediated mechanisms of the cellular stress response in atherosclerosis. Nat Rev Cardiol. 2015;12(6):361–374.
   PubMed Web of Science ®Google Scholar
• Loyer X, Potteaux S, Vion A-C, et al. Inhibition of miRNA-92a prevents endothelial dysfunction and atherosclerosis in mice. Circ Res. 2014;114(3):434–443.
   PubMed Web of Science ®Google Scholar
• Schober A, Nazari-Jahantigh M, Wei Y, et al. MiRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1. Nat Med. 2014;20(4):368–376.
   PubMed Web of Science ®Google Scholar
• Knoepp K, Dutzmann J, Donde K, et al. P3201 MicroRNA-494-A crucial player in smooth muscle cell proliferation and vascular remodeling. Eur Heart J. 2018;39(suppl_1):ehy563–P3201.
   Google Scholar
• Verjans R, Peters T, Beaumont FJ, et al. MicroRNA-221/222 family counteracts myocardial fibrosis in pressure overload–induced heart failure. Hypertension. 2018;71(2):280–288.
   PubMed Web of Science ®Google Scholar
• Hergenreider E, Heydt S, Treguer K, et al. Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol. 2012;14(3):249–256.
   PubMed Web of Science ®Google Scholar
• Cordes KR, Sheehy NT, White MP, et al. miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature. 2009;460(7256):705–710.
   PubMed Web of Science ®Google Scholar
• Nazarijahantigh M, Wei Y, Noels H, et al. MiRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages. J Clin Invest. 2012;122(11):4190–4202.
   PubMed Web of Science ®Google Scholar
• Hao L, Wang XG, Cheng JD, et al. The up-regulation of endothelin-1 and down-regulation of miRNA-125a-5p, -155, and -199a/b-3p in human atherosclerotic coronary artery. Cardiovasc Pathol. 2014;23(4):217–223.
   PubMed Web of Science ®Google Scholar
• Zhong L, Simard MJ, Huot J. Endothelial microRNAs regulating the NF-κB pathway and cell adhesion molecules during inflammation. FASEB J. 2018;32(8):fj201701536R.
   Web of Science ®Google Scholar
• Harris TA, Yamakuchi M, Ferlito M, et al. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. PNAS. 2008;105(5):1516–1521.
   PubMed Web of Science ®Google Scholar
• Lovren F, Pan Y, Quan A, et al. MiRNA-145 targeted therapy reduces atherosclerosis. Circulation. 2012;126(11_suppl_1):S81–S90.
   PubMed Web of Science ®Google Scholar
• Cheng HS, Besla R, Li A, et al. Paradoxical suppression of atherosclerosis in the absence of miRNA-146a. Circ Res. 2017;121(4):354–367.
   PubMed Web of Science ®Google Scholar
• Chen WJ, Yin K, Zhao GJ, et al. The magic and mystery of miRNA-27 in atherosclerosis. Atherosclerosis. 2012;222(2):314–323.
   PubMed Web of Science ®Google Scholar
• Bao J, Zhou S, Pan S, et al. Molecular mechanism exploration of ischemic stroke by integrating mRNA and miRNA expression profiles. Clin Lab. 2018;64(04/2018):559–568.
   PubMed Web of Science ®Google Scholar
• Vijayan M, Kumar S, Yin X, et al. Identification of novel circulatory miRNA signatures linked to patients with ischemic stroke. Hum Mol Genet. 2018;27(13):2318–2329.
   PubMed Web of Science ®Google Scholar
• Kim JO, Bae J, Kim J, et al. Association of MiRNA biogenesis genes polymorphisms with ischemic stroke susceptibility and post-stroke mortality. J Stroke. 2018;20(1):110–121.
   PubMed Web of Science ®Google Scholar
• Maitrias P, Metzinger-Le Meuth V, Nader J, et al. The involvement of miRNA in carotid-related stroke. Arterioscler Thromb Vasc Biol. 2017;37(9):1608–1617.
   PubMed Web of Science ®Google Scholar
• Mirzaei H, Momeni F, Saadatpour L, et al. MiRNA: relevance to stroke diagnosis, prognosis, and therapy. J Cell Physiol. 2018;233(2):856–865.
   PubMed Web of Science ®Google Scholar
• Chen W, Sinha B, Li Y, et al. Monogenic, polygenic, and MiRNA markers for ischemic stroke. Mol Neurobiol. 2019;56(2):1330–1343
   PubMed Web of Science ®Google Scholar
• Jickling GC, Ander BP, Shroff N, et al. Leukocyte response is regulated by miRNA let7i in patients with acute ischemic stroke. Neurology. 2016;87(21):2198–2205.
   PubMed Web of Science ®Google Scholar
• Luo YP, Li Q, Deng ZF, et al. Systematic analysis of RNA regulatory network in rat brain after ischemic stroke. BioMed Res Int. 2018;2018:1–13.
   Web of Science ®Google Scholar
• Liu W, Chen X, Zhang Y. Effects of miRNA-21 and miRNA-24 inhibitors on neuronal apoptosis in ischemic stroke. Am J Transl Res. 2016;8(7):3179.
   PubMed Web of Science ®Google Scholar
• Scherrer N, Fays F, Mueller B, et al. MiRNA 150-5p improves risk classification for mortality within 90 days after acute ischemic stroke. J Stroke. 2017;19(3):323–332.
   PubMed Web of Science ®Google Scholar
• Duris K, Lipkova J. The role of miRNA in ischemic and hemorrhagic stroke. Current Drug Delivery. 2016;13(999):1–1.
   Google Scholar
• Weiss JB, Eisenhardt SU, Stark GB, et al. MiRNAs in ischemia-reperfusion injury. Am J Cardiovasc Dis. 2012;2(3):237–247####247.
   PubMedGoogle Scholar
• Zhu F, Liu JL, Li JP, et al. MiRNA-124 (miRNA-124) regulates Ku70 expression and is correlated with neuronal death induced by ischemia/reperfusion. J Mol Neurosci. 2014;52(1):148–155.
   PubMed Web of Science ®Google Scholar
• Uhlmann S, Mracsko E, Javidi E, et al. Genome-Wide analysis of the circulating miRNome after cerebral ischemia reveals a reperfusion-induced MiRNA cluster. Stroke. 2017;48(3):762–013942. STROKEAHA.
   PubMed Web of Science ®Google Scholar
• Miao W, Bao TH, Han JH, et al. Neuroprotection induced by post-conditioning following ischemia/reperfusion in mice is associated with altered miRNA expression. Mol Med Rep. 2016;14(3):2582–2588.
   PubMed Web of Science ®Google Scholar
• Liang Y, Xu J, Wang Y, et al. Inhibition of MiRNA-125b decreases cerebral ischemia/reperfusion injury by targeting CK2α/NADPH oxidase signaling. Cell Physiol Biochem. 2018;45(5):1818.
   PubMedGoogle Scholar
• Jin F, Xing J. Circulating pro-angiogenic and anti-angiogenic miRNA expressions in patients with acute ischemic stroke and their association with disease severity. Neurol Sci. 2017;38(11):2015–2023.
   PubMed Web of Science ®Google Scholar
• Pankratz F, Bemtgen X, Zeiser R, et al. 155 Exerts cell-specific antiangiogenic but proarteriogenic effects during adaptive neovascularization. Circulation. 2015;131(18):1575–1589.
   PubMed Web of Science ®Google Scholar
• Kaluza D, Kroll J, Gesierich S, et al. Histone deacetylase 9 promotes angiogenesis by targeting the antiangiogenic miRNA-17-92 cluster in endothelial cells. Arterioscler Thromb Vasc Biol. 2013;33(3):533.
   PubMed Web of Science ®Google Scholar
• Toit AD. RNA: circular RNAs as miRNA sponges. Nat Rev Mol Cell Biol. 2013;14(4):195.
   Google Scholar
• Piwecka M, Glažar P, Hernandez-Miranda LR, et al. Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function. Science. 2017;357(6357):eaam8526.
   PubMed Web of Science ®Google Scholar
• Holdt LM, Stahringer A, Sass K, et al. Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans. Nat Commun. 2016;7(1):12429.
   PubMed Web of Science ®Google Scholar
• Mehta SL, Pandi G, Vemuganti R. Circular RNA expression profiles alter significantly in mouse brain after transient focal ischemia. Stroke. 2017;48(9):2541–2548.
   PubMed Web of Science ®Google Scholar