Systemic immune-inflammation index (SII) but not platelet-albumin-bilirubin (PALBI) grade is associated with severity of acute ischemic stroke (AIS)

References

• Lambertsen KL, Biber K, Finsen B. Inflammatory cytokines in experimental and human stroke. J Cereb Blood Flow Metab. 2012;32(9):1677–1698.
   PubMed Web of Science ®Google Scholar
• Xue J, Huang W, Chen X, et al. Neutrophil-to-lymphocyte ratio is a prognostic marker in acute ischemic stroke. J Stroke Cerebrovasc Dis. 2017;26(3):650–657.
   PubMed Web of Science ®Google Scholar
• Ren H, Liu X, Wang L, et al. Lymphocyte-to-monocyte ratio: a novel predictor of the prognosis of acute ischemic stroke. J Stroke Cerebrovasc Dis. 2017;26(11):2595–2602.
   PubMed Web of Science ®Google Scholar
• Thakkar M, Edelenbos J, Dore S. Bilirubin and ischemic stroke: rendering the current paradigm to better understand the protective effects of bilirubin. Mol Neurobiol. 2019;56(8):5483–5496.
   PubMed Web of Science ®Google Scholar
• Yu H, Huang Y, Chen X, et al. High-sensitivity C-reactive protein in stroke patients – the importance in consideration of influence of multiple factors in the predictability for disease severity and death. J Clin Neurosci. 2017;36:12–19.
   PubMed Web of Science ®Google Scholar
• Kumral E, Saruhan G, Aktert D, et al. Association of hyperhomocysteinemia with stroke recurrence after initial stroke. J Stroke Cerebrovasc Dis. 2016;25(8):2047–2054.
   PubMed Web of Science ®Google Scholar
• Hu B, Yang XR, Xu Y, et al. Systemic immune-inflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma. Clin Cancer Res. 2014;20(23):6212–6222.
   PubMed Web of Science ®Google Scholar
• Chen JH, Zhai ET, Yuan YJ, et al. Systemic immune-inflammation index for predicting prognosis of colorectal cancer. World J Gastroenterol. 2017;23(34):6261–6272.
   PubMed Web of Science ®Google Scholar
• Lu LH, Zhang YF, Mu-Yan C, et al. Platelet-albumin-bilirubin grade: risk stratification of liver failure, prognosis after resection for hepatocellular carcinoma. Dig Liver Dis. 2019;51(10):1430–1437.
   PubMedGoogle Scholar
• Johnson PJ, Berhane S, Kagebayashi C, et al. Assessment of liver function in patients with hepatocellular carcinoma: a new evidence-based approach-the ALBI grade. J Clin Oncol. 2015;33(6):550–558.
   PubMed Web of Science ®Google Scholar
• Anrather J, Iadecola C. Inflammation and stroke: an overview. Neurotherapeutics. 2016;13(4):661–670.
   PubMed Web of Science ®Google Scholar
• Jin R, Yang G, Li G. Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J Leukoc Biol. 2010;87(5):779–789.
   PubMed Web of Science ®Google Scholar
• Iadecola C, Anrather J. The immunology of stroke: from mechanisms to translation. Nat Med. 2011;17(7):796–808.
   PubMed Web of Science ®Google Scholar
• Zhao BQ, Wang S, Kim HY, et al. Role of matrix metalloproteinases in delayed cortical responses after stroke. Nat Med. 2006;12(4):441–445.
   PubMed Web of Science ®Google Scholar
• Zhou W, Liesz A, Bauer H, et al. Postischemic brain infiltration of leukocyte subpopulations differs among murine permanent and transient focal cerebral ischemia models. Brain Pathol. 2013;23(1):34–44.
   PubMed Web of Science ®Google Scholar
• Akopov SE, Simonian NA, Grigorian GS. Dynamics of polymorphonuclear leukocyte accumulation in acute cerebral infarction and their correlation with brain tissue damage. Stroke. 1996;27(10):1739–1743.
   PubMed Web of Science ®Google Scholar
• Li GZ, Zhong D, Yang LM, et al. Expression of interleukin-17 in ischemic brain tissue. Scand J Immunol. 2005;62(5):481–486.
   PubMed Web of Science ®Google Scholar
• Schwartz M, Moalem G. Beneficial immune activity after CNS injury: prospects for vaccination. J Neuroimmunol. 2001;113(2):185–192.
   PubMed Web of Science ®Google Scholar
• Yilmaz G, Arumugam TV, Stokes KY, et al. Role of T lymphocytes and interferon-gamma in ischemic stroke. Circulation. 2006;113(17):2105–2112.
   PubMed Web of Science ®Google Scholar
• Ooboshi H, Ibayashi S, Shichita T, et al. Postischemic gene transfer of interleukin-10 protects against both focal and global brain ischemia. Circulation. 2005;111(7):913–919.
   PubMed Web of Science ®Google Scholar
• Maugeri N, Rovere-Querini P, Evangelista V, et al. Neutrophils phagocytose activated platelets in vivo: a phosphatidylserine, P-selectin, and β2 integrin-dependent cell clearance program. Blood. 2009;113(21):5254–5265.
   PubMed Web of Science ®Google Scholar
• Blair P, Rex S, Vitseva O, et al. Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinase. Circ Res. 2009;104(3):346–354.
   PubMed Web of Science ®Google Scholar
• Meisel C, Schwab JM, Prass K, et al. Central nervous system injury-induced immune deficiency syndrome. Nat Rev Neurosci. 2005;6(10):775–786.
   PubMed Web of Science ®Google Scholar
• Stanzani L, Zoia C, Sala G, et al. Nerve growth factor and transforming growth factor-beta serum levels in acute stroke patients. Possible involvement of neurotrophins in cerebrovascular disease. Cerebrovasc Dis. 2001;12(3):240–244.
   PubMed Web of Science ®Google Scholar
• Członkowska A, Cyrta B, Korlak J. Immunological observations on patients with acute cerebral vascular disease. J Neurol Sci. 1979;43(3):455–464.
   PubMed Web of Science ®Google Scholar
• Elenkov IJ, Wilder RL, Chrousos GP, et al. The sympathetic nerve–an integrative interface between two supersystems: the brain and the immune system. Pharmacol Rev. 2000;52(4):595–638.
   PubMed Web of Science ®Google Scholar
• Prass K, Meisel C, Höflich C, et al. Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell type 1-like immunostimulation. J Exp Med. 2003;198(5):725–736.
   PubMed Web of Science ®Google Scholar
• Arbel Y, Finkelstein A, Halkin A, et al. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography. Atherosclerosis. 2012;225(2):456–460.
   PubMed Web of Science ®Google Scholar
• Koklu E, Yuksel IO, Arslan S, et al. Is elevated neutrophil-to-lymphocyte ratio a predictor of stroke in patients with intermediate carotid artery stenosis? J Stroke Cerebrovasc Dis. 2016;25(3):578–584.
   PubMed Web of Science ®Google Scholar
• Easton AS. Neutrophils and stroke – can neutrophils mitigate disease in the central nervous system? Int Immunopharmacol. 2013;17(4):1218–1225.
   PubMed Web of Science ®Google Scholar