156
Views
11
CrossRef citations to date
0
Altmetric
Original Articles

Fabrication of Poly(D,L-lactide-co-glycolide) Microspheres and Degradation Characteristics in vitro

&
Pages 1682-1690 | Received 01 Jun 2010, Accepted 02 Aug 2010, Published online: 10 Aug 2011

References

  • Ouchi , T. and Ohya , Y. 2004 . Design of lactide copolymers as biomaterials . J. Polym. Sci. Part A Polym. Chem. , 42 : 453 – 462 .
  • Albertsson , A. C. and Varma , I. K. 2003 . Recent developments in ring opening polymerization of lactones for biomedical applications . Biomacromolecules , 4 : 1466 – 1486 .
  • Jain , R. A. 2000 . The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices . Biomaterials , 21 : 2475 – 2490 .
  • Freiberg , S. and Zhu , X. 2004 . Polymer microspheres for controlled drug release . Int. J. Pharm. , 282 : 1 – 18 .
  • Berkland , C. , King , M. , Cox , A. , Kim , K. and Pack , D. W. 2002 . Precise control of PLG microsphere size provides enhanced control of drug release rate . J. Control. Release , 82 : 137 – 147 .
  • Jiang , W. , Gupta , R. K. , Deshpande , M. C. and Schwendeman , S. P. 2005 . Biodegradable poly(lactic-co-glycolic acid) microparticles for injectable delivery of vaccine antigens . Adv. Drug Deliv. Rev. , 57 : 391 – 410 .
  • Seong , H. , An Tae , K. , Khang , G. , Choi , S. , Lee , C. O. and Lee , H. B. 2003 . BCNU-loaded poly(D,L-lactide-co-glycolide) wafer and antitumor activity against XF-498 human CNS tumor cells in vitro . Int. J. Pharm. , 251 : 1 – 12 .
  • Benny , O. , Duvshani-Eshet , M. , Cargioli , T. , Bello , L. , Bikfalvi , A. , Carroll , R. S. and Machluf , M. 2005 . Continuous delivery of endogenous inhibitors from poly(lactic-co-glycolic acid) polymeric microspheres inhibits glioma tumor growth . Clin. Cancer Res. , 11 : 768 – 776 .
  • Edlund , U. and Albertsson , A. C. 2002 . Degradable polymer microspheres for controlled drug delivery . Adv. Polym. Sci. , 157 : 67 – 112 .
  • He , Z. and Xiong , L. 2009 . Preparation and in vitro degradation behavior of poly(L-lactide-co-glycolide) by direct-melt polycondensation . J. Macromol. Sci. Phys. , 48 : 789 – 798 .
  • He , Z. and Xiong , L. 2010 . A comparative study on in vitro degradation behaviors of poly(L-lactide-co-glycolide) scaffolds and films . J. Macromol. Sci. Phys. , 49 : 25 – 33 .
  • Dunne , M. , Corrigan , O. J. and Ramtoola , Z. 2000 . Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles . Biomaterials , 21 : 1659 – 1668 .
  • Liu , R. , Huang , S. S. , Wan , Y. H. , Ma , G. H. and Su , Z. G. 2006 . Preparation of insulinloaded PLA/PLGA microcapsules by a novel membrane emulsification method and its release in vitro . Colloids Surf B: Biointerfaces , 51 : 30 – 38 .
  • Yang , Y. Y. , Chia , H. H. and Chung , T. S. 2000 . Effects of preparation temperature in the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method . J. Control. Release , 69 : 81 – 96 .
  • Lee , J. S. , Chae , G. S. , Kim , M. S. , Cho , S. H. , Lee , H. B. and Khang , G. 2004 . Degradation behaviour in vitro for poly(D,L-lactide-co-glycolide) as drug carrier . Bio-Med. Mater. Eng. , 14 : 185 – 192 .
  • Dueka , E. A.R. , Zavaglia , C. A.C. and Belangero , W. D. 1999 . In vitro study of poly(lactic acid) pin degradation . Polymer , 40 : 6465 – 6473 .
  • Wang , D. , Robinson , D. R. , Kwon , G. S. and Samuel , J. 1999 . Encapsulation of plasmid DNA in biodegradable poly(D,L-lactic-co-glycolic acid) microspheres as a novel approach for immunogene delivery . J. Control. Release , 57 : 9 – 18 .
  • Blanco , M. D. , Sastre , R. L. , Teijón , C. , Olmo , R. and Teijón , J. M. 2006 . Degradation behaviour of microspheres prepared by spray-drying poly(d,l-lactide) and poly(d,l-lactide-co-glycolide) polymers . Int. J. Pharm. , 326 : 139 – 147 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.