Molecular genetics of melanocytic neoplasia: practical applications for diagnosis

References

• Farmer ER, Gonin R, Hanna MP. Discordance in the histopathologic diagnosis of melanoma and melanocytic nevi between expert pathologists. Hum Pathol 1996; 27: 528–31.
   Google Scholar
• Spatz A, Ruiter D, Hardmeier T, et al. Melanoma in childhood: an EORTC-MCG multicenter study on the clinico-pathological aspects. Int J Cancer 1996; 68: 317–24.
   PubMed Web of Science ®Google Scholar
• Veenhuizen KC, De Wit PE, Mooi WJ, et al. Quality assessment by expert opinion in melanoma pathology: experience of the pathology panel of the Dutch Melanoma Working Party. (See comments.) J Pathol 1997; 182: 266–72.
   PubMed Web of Science ®Google Scholar
• Troxel DB, Sabella JD. Problem areas in pathology practice. Uncovered by a review of malpractice claims. (See comments.) Am J Surg Pathol 1994; 18: 821–31.
   PubMed Web of Science ®Google Scholar
• Jackson R. Malignant melanoma: a review of 75 malpractice cases. Int J Dermatol 1997; 36: 497–8.
   PubMed Web of Science ®Google Scholar
• Bastian BC, LeBoit PE, Hamm H, et al. Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization. Cancer Res 1998; 58: 2170–5.
   PubMed Web of Science ®Google Scholar
• Bastian BC, Wesselmann U, Pinkel D, et al. Molecular cytogenetic analysis of Spitz nevi show clear differences to melanoma. J Invest Dermatol 1999; 113: 1065–1069.
   PubMed Web of Science ®Google Scholar
• Harris N L, Jaffe E S, Stein H, et al. A revised European-American classification of lymphoid neoplasms: a proposal from the Interna-tional Lymphoma Study Group. Blood 1994; 84: 1361–92.
   PubMed Web of Science ®Google Scholar
• Mauro MJ, Druker BJ. 5TI571: targeting BCR-ABL as therapy for CML. Oncologist 2001; 6: 233–8.
   PubMed Web of Science ®Google Scholar
• Snijders AM, Nowak N, Segraves R, et al. Assembly of microarrays for genome-wide measurement of DNA copy number. Nat Genet 2001; 29: 263–4.
   PubMed Web of Science ®Google Scholar
• Bastian BC, Olshen A, LeBoit PE, et al. Classification of melanocytic tumors by DNA copy number changes. Am J Pathol 2003; 163: 1765–70.
   PubMed Web of Science ®Google Scholar
• Bastian BC, LeBoit PE, Pinkel D. Mutations and copy number increases of HRAS in Spitz nevi with distinctive histopathologic features. Am J Pathol 2000; 157: 967–72.
   Google Scholar
• Pollock PM, Harper UL, Hansen KS, et al. High frequency of BRAF mutations in nevi. Nat Genet 2002; 25: 25.
   Google Scholar
• Yazdi AS, Palmedo G, Flaig MJ, et al. Mutations of the BRAF gene in benign and malignant melanocytic lesions. J Invest Dermatol 2003; 121: 1160–2.
   PubMed Web of Science ®Google Scholar
• Kamb A, Shattuck-Eidens D, Eeles R, et al. Analysis of the p16 gene CDKN2 as a candidate for the chromosome 9p melanoma suscept-ibility locus. Nat Genet 1994; 8: 23–6.
   PubMed Web of Science ®Google Scholar
• Maldonado JL, Fridlyand J, Timmerman L, et al. Mechanisms of cell cycle arrest in Spitz nevi with constitutive activation of the MAP-kinase pathway. Am J Pathol 2004; 164: 1783–7.
   PubMed Web of Science ®Google Scholar
• Serrano M, Lin AW, McCurrach ME, et al. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and pl6INK4a. Cell 1997; 88: 593–602.
   PubMed Web of Science ®Google Scholar
• Mathon NF, Lloyd AC. Cell senescence and cancer. Nat Rev Cancer 2001; 1: 203–13.
   PubMed Web of Science ®Google Scholar
• Bandyopadhyay D, Medrano EE. Melanin accumulation accelerates melanocyte senescence by a mechanism involving p16INK4a/CDK4/ pRB and E2F1. Ann N Y Acad Sci 2000; 908: 71–84.
   PubMed Web of Science ®Google Scholar
• Sviderskaya EV, Hill SP, Evans-Whipp Ti, et al. p16(Ink4a) in melanocyte senescence and differentiation. J Natl Cancer Inst 2002; 94: 446–54.
   PubMedGoogle Scholar
• Funk JO, Schiller PI, Barrett MT, et al. pl6INK4a expression is frequently decreased and associated with 9p21 loss of heterozygosity in sporadic melanoma. J Cutan Pathol 1998; 25: 291–6.
   PubMed Web of Science ®Google Scholar
• Ohtani N, Zebedee Z, Huot Ti, et al. Opposing effects of Ets and Id proteins on pl6INK4a expression during cellular senescence. Nature 2001; 409: 1067–70.
   PubMed Web of Science ®Google Scholar
• Bastian BC. Hypothesis: a role for telomere crisis in spontaneous regression of melanoma. Arch Dermatol 2003; 139: 667–8.
   PubMedGoogle Scholar
• Ramirez RD, D'Atri S, Pagani E, et al. Progressive increase in telomerase activity from benign melanocytic conditions to malignant melanoma. Neoplasia 1999; 1: 42–9.
   PubMedGoogle Scholar
• Greenberg RA, Chin L, Femino A, et al. Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse. Cell 1999; 97: 515–25.
   PubMed Web of Science ®Google Scholar
• Zimonjic D, Brooks MW, Popescu N, et al. Derivation of human tumor cells in vitro without widespread genomic instability. Cancer Res 2001; 61: 8838–44.
   PubMed Web of Science ®Google Scholar