A FACILE SYNTHETIC ROUTE TO HYDROXY METABOLITES OF TRICYCLIC ANTIDEPRESSANTS

References

• Schindler , W. 1960 . Helv. Chim. Acta , 43 : 35
   Google Scholar
• Fraser , A. D. , Isner , A. F. and Perry , R. F. 1987 . J. Anal. Toxicol. , 11 : 168
   PubMed Web of Science ®Google Scholar
• Suckow , R. F. and Cooper , T. B. 1984 . J. Pharm. Sci. , 73 : 1745 and references therein
   PubMed Web of Science ®Google Scholar
• Herrmann , B. and Pulver , R. 1960 . Archs. Int. Pharmacodyn. , 126 : 454
   PubMedGoogle Scholar
• Koch , S. S. C. and Chamberlin , A. 1989 . Syn. Comm. , 19 : 829
   Google Scholar
• De Jongh , G. D. , van den Wildenberg , H. M. , Nieuwenhuyse , H. and van der Veen , F. 1981 . Drug Metab. Dispos. , 9 : 48
   PubMed Web of Science ®Google Scholar
• van Boeckel , C. A. A. , Delbressine , L. P. C. and Kaspersen , F. M. 1985 . Recl. Trav. Chim. Pays-Bas. , 104 : 259
   Google Scholar
• Differential NOE and 2D-COSY NMR experiments support the assigned structures for the phenolic metabolites 3a, 3b, 6 and 13
   Google Scholar
• Borch , R. F. 1972 . Org. Syn. , 52 : 124
   Google Scholar
• The phenolic metabolites, 3a, 3b, 6 and 13, are not stable to heat and slowly decomposed during drying to afford compounds which did not give satisfactory elemental analyses
   Google Scholar