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OPPI BRIEFS

THE SYNTHESIS OF 3-AMINO-2-DIALKYLAMINOPYRIDINES

Pages 709-713 | Received 28 Apr 1998, Published online: 09 Feb 2009

References

  • Meth-Cohn , O. , Smalley , R. K. and Suschitzky , H. 1963 . J. Chem. Soc. , : 1666
  • Schickh , O. V. , Binz , A. and Schulz , A. 1936 . Ber. , 69 : 2593
  • Dunn , A. D. , Currie , A. and Hayes , L. E. 1989 . J. prakt. Chem. , 331 : 369
  • Urban , R. and Schneider , O. 1964 . Helv. Chim. Acta , 47 : 363
  • Theoretical calculations (PM3 and MNDO) carried out by Professor W. Schroth at the University of Halle indicate that there is little difference in the preference for substitution at the 2 and 6 positions in 4. We gratefully acknowledge this work
  • Plazek , E. and Marcinkow , A. 1934 . Rocz. Chem. , 14 : 326 Chem. Abstr 29, 2535 (1935). A compound of this structure, mp. 210° has been reported
  • Jain , P. C. , Kapoor , V. , Anand , N. , Ahmad , A. and Patnaik , G. K. 1967 . J. Med. Chem. , 10 : 812 This is clearly a typographical error or the mp. of the hydrochloride, since a sample prepared by the method outlined in this reference had mp., mmp, IR and NMR identical to the samples prepared by us. Its dihydrochloride was also indistinguishable from the dihydrochloride mentioned in this publication
  • Thunus , L. and Lapiere , C. L. 1974 . Ann. Pharm. Franc. , 32 : 569

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