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Pathology Volume 33, 2001 - Issue 4
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Research Article

Effect of Transforming Growth Factor- β 1, Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-II on Cell Growth and Oestrogen Metabolism in Human Breast Cancer Cell Lines

Fung Wong, Karin Reimann, Leslie C. Lai Department of Clinical Laboratory Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
Pages 454-459 | Published online: 06 Jul 2009

  • Massague J, Blain SW, Lo RS. TGFß signalling in growth control, cancer, and heritable disorders. Cell 2000; 103: 295-309.
  • Ariazi EA, Satomi Y, Ellis MJ, et al Activation of transforming growth factor-ß signalling pathway and induction of cytostasis and apoptosis in mammary carcinomas treated with the anticancer agent perillyl alcohol. Cancer Res 1999; 59: 1917-28.
  • Alexandrow MG, Moses HL. Transforming growth factor-ß and cell cycle regulation. Cancer Res 1995; 55: 1452-7.
  • Welch DR, Fabra A, Nakajima M. Transforming growth factor ß stimulates mammary adenocarcinoma cell invasive and metastatic potential. Proc Natl Acad Sci USA 1990; 87: 7678-82.
  • Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 1995; 16: 3-34.
  • Singh A, Reed MJ. Insulin-like growth factor type I and insulin-like growth factor type II stimulate aestradiol-17ß-hydroxysteroid dehydrogenase (reductive) activity in breast cancer cells. J Endocrinol 1991; 129: R5-8.
  • Hwa IA, Reimann K, Lim PK, Lai LC. Effects of Insulin-like growth factors I and II on oestrone sulphatase activity in human breast cancer cell lines. Int J Mol Med 1999; 4: 175-8.
  • Purohit A, Chapman O, Duncan L, Reed MJ. Modulation of oestrone sulphatase activity in breast cancer cell lines by growth factors. J Steroid Biochem Mol BM 1992; 41: 563-6.
  • Ruder HI, Loriaux L, Lipsett MB. Oestrone sulphate: production rate and metabolism in man. J Clin Invest 1972; 51: 1020-33.
  • Pasqualini JR, Gelly C, Nguyen BL. Metabolism and biologic response of oestrogen sulphates in hormone-dependent and hormoneindependent mammary cancer cell lines. Effect of antioestrogens. Ann NY Acad Sci 1989; 684: 106-16.
  • Beranek PA, Folkerd EI, Newton CJ, Reed MJ, Ghilchik MW, James VHT. The relationship between 17ß hydroxysteroid dehydrogenase and breast tumour site and size. Int J Cancer 1985; 36: 685-7.
  • Prudhomme JF, Malet C, Compel A, et al 17ß-Hydroxysteroid dehydrogenase activity in human breast epithelial cell and fibroblast cultures. Endocrinology 1984; 114: 1483-9.
  • Ee YS, Lai LC, Reimann K, Lim PK. Effect of transforming growth factor-ß1 1 on oestrogen metabolism in MCF-7 and MDA-MB-231 breast cancer cell lines. Oncol Rep 1999; 6: 843-6.
  • Cheifetz S, Weatherbee JA, Tsang ML, et al. The transforming growth factor-ß system, a complex pattern of cross-reactive ligands and receptors. Cell 1987; 48: 409-15.
  • Karey KP, Sirbasku DA. Differential responsiveness of human breast cancer cell lines MCF-7 and T47D to growth factors and 17ß-oestradiol. Cancer Res 1988; 48: 4083-92.
  • Reed MJ, Purohit A, Duncan LJ, et al The role of cytokines and sulphatase inhibitors in regulating oestrogen synthesis in breast tumours. J Steroid Biochem Mol Biol 1995; 53: 413-20.
  • Osborne CK, Hobbs K, Trent JM. Biological differences among MCF7 human breast cancer cell lines from different laboratories. Breast Cancer Res Treat 1987; 9: 111-21.
  • Stewart AJ, Westley BR, May FE. Modulation of the proliferative response of breast cancer cells to growth factors by oestrogen. Br J Cancer 1992; 66: 640-8.
  • Osborne CK, Clemmons DR, Arteaga CL. Regulation of breast cancer growth by insulin-like growth factors. J Steroid Biochem Mol Biol 1990; 37: 805-9.
  • Gucev ZS, Oh Y, Kelley KM, Rosenfeld RG. Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor ß2-induced growth inhibition in human breast cancer cells. Cancer Res 1996; 56: 1545-50.
  • Pratt SE, Pollak MN. Insulin-like growth factor binding protein-3 (IGF-BP3) inhibits oestrogen-stimulated breast cancer cell proliferation. Biochem Biophys Res Commun 1994; 198: 292-7.
  • Cohick WS, Wang B, Verma P, Boisclair YR. Insulin-like growth factor I (IGF-I) and cyclic adenosine 3',5'-monophosphate regulate IGF-binding protein-3 gene expression by transcriptional and posttranscriptional mechanisms in mammary epithelial cells. Endocrinology 2000; 141:4583-91.
  • Purohit A, Wang DY, Ghilchik MW, Reed MJ. Regulation of aromatase and sulphatase in breast tumour cells. J Endocrinol 1996; 150: S65-71.
  • Purohit A, De Giovani CV, Reed MJ. The regulation of oestrone sulphate formation in breast cancer cells. J Steroid Biochem MoI Biol 1999; 68: 129-35.

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