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Pathology Volume 33, 2001 - Issue 4
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Research Article

Expression of Cyclooxygenase-1 and-2 in Urinary Bladder Carcinomas In Vivo and In Vitro and Prostaglandin E 2 Synthesis in Cultured Bladder Cancer Cells

Peter Boström, Vesa Aaltonen, Karl-Ove Söderström, Pekka Uotila, Matti Maato Physiology, University of Turku, Turku, Finland
Pages 469-474 | Published online: 06 Jul 2009

  • Finnish Cancer Registry. Cancer incidence in Finland 1995. In: Cancer Statistics cf the National Research and Development Centre for Welfare and Health. Cancer Society of Finland publication Na 58. Helsinki: Finnish Cancer Registry, 1997.
  • Cordon-Cardo C, Sheinfeld J. Molecular and immunopathology studies of oncogenes and tumour-suppressor genes in bladder cancer. World J UroI 1997; 15: 112-9.
  • Aaltonen V, Boströra PJ, Söderström K-O, et al Urinary bladder transitional cell carcinogenesis is associated with down-regulation of NFl tumour suppressor gene in vivo and in vitra Am J Pathol 1999; 154: 755-65.
  • Williams CS, DuBois RN. Prostaglandin endoperoxide synthase: why two isoforms? Am J Physiol 1996; 270: 393-400.
  • Sano H, Kawahito Y, Wilder RL,et al. Expression of cyclooxygenase --1 and -2 in human colorectal cancer. Cancer Res 1995; 55: 3785-9.
  • Ristimaki A, Honkanen N, Jänkälä H, et al. Expression of cyclooxygenase-2 in human gastric carcinoma. Cancer Res 1997; 57: 1276-80.
  • Zimmermann KC, Sarbia M, Weber A-A, et al. Cyclooxygenase-2 expression in human esophageal carcinoma. Cancer Res 1999; 59: 198-204.
  • Wdff H, Saukkonen K, Anttila S, et al. Expression of cyclooxygenase --2 in human lung carcinoma. Cancer Res 1998; 58: 4997-5001.
  • Hida T, Yatabe Y, Achiwa H, et al. Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas. Cancer Res 1998; 58: 3761-4.
  • Tucker ON, Dannenberg AJ, Yang EK, et al. Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer Res 1999; 59: 987-90.
  • Koga H, Sakisaka S, Ohishi M, et al. Expression of cyclooxygenase- 2 in human hepatocellular carcinoma: relevance to tumor dedifferentiation. Hepatology 1999; 29: 689-96.
  • Hwang D, Scollard D, Byrne J, et al. Expression of cyclooxygenase-1 and cyclooxygenase-2 in human breast cancer. J Natl Cancer lnst 1998; 90: 455-60.
  • Thun MI, Namboodiri MM, Heath CW Jr. Aspirin use and reduced risk of fatal colon cancer. New Engl J Med 1991 ; 325: 1593-6.
  • Moon RC, Kelloff GJ, Detrisac CJ, et al Chemoprevention of OHBBN-induced bladder cancer in mice by piroxicam. Carcinogenesis 1993; 14: 1487-9.
  • Rao KV, Detrisac CJ, Steele VE, et al Differential activity of aspirin, ketoprofen and sulindac as cancer chemopreventive agents in the mouse urinary bladder. Carcinogenesis 1996; 17: 1435-8.
  • Okajima E, Denda A, Ozono S, et al Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on development of rat urinary bladder carcinomas initiated by N-butylN-(4-hydroxybutyl)nitrosamine. Cancer Res 1998; 58: 3028-31.
  • Mostofi FK, Sobin LH, Torloni H. Histological Typing of Urinary Bladder Tumours. Geneva: World Health Organization (WHO), 1973.
  • Chirgwin JM, Przybyla AE, MacDonald RJ, et al. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979; 18: 5294-9.
  • Isoherranen K, Punnonen K, Iansen C, et al. Ultraviolet irradiation induces cyclooxygenase-2 expression in keratinocytes. Br J Dermatol 1999; 140: 1017-22.
  • Tsujii M, Kawano S, Tsuji S, et al Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell 1998; 93: 705-16.
  • Tjandrawinata RR, Dahiya R, Hughes-Fulford M. Induction of cyclooxygenase mRNA by prostaglandin E2 in human prostatic carcinoma cells. Br J Cancer 1997; 75:1111-8.
  • Lu X, Xie W, Reed D, et al Nonsteroidal antiinflammatory drugs cause apoptosis and induce cyclcoxygenases in chicken embryo fibroblasts. Proc Natl Acad Sci USA 1995; 92: 7961-5.
  • Eling TE, Thompson DC, Foureman GL, et al Prostaglandin H synthase and xenobiotic oxidation. Anna Rev Pharmacol Toxicol 1990; 30: 1-45.
  • Sheng H, Shaol, Morrow ID, et al. Modulation of apoptosis and bcl-2 expression by prostaglandin E2 in human colon cancer cells. Cancer Res 1998; 58: 362-6.
  • Uotila P. The role of cyclic AMP and oxygen intermediates in the inhibition of cellular immunity in cancer. Cancer Immunol Immunother 1996; 43: 1-9.
  • Subbaramaiah K, Telang N, Ramonetti IT, et al Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells. Cancer Res 1996; 56: 4424-9.
  • Mohammed SI, Knapp DW, Bostwick DG, et al Expression of cyclooxygenase-2 (COX-2) in human invasive transitional cell carcinoma (TCC) of the urinary bladder. Cancer Res 1999; 59: 5647-50.

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