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Pathology Volume 33, 2001 - Issue 3
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Research Article

MULTIPLE SMALL INTESTINAL STROMAL TUMOURS IN A PATIENT WITH PREVIOUSLY UNRECOGNISED NEUROFIBROMATOSIS TYPE 1: IMMUNOHISTOCHEMICAL AND ULTRASTRUCTURAL EVALUATION

Renzo Boldorini, Antonella Tosoni, Monica Leutner, Raffaella Ribaldone, Nicola Surico, Erika Comello, Kyung-Whan Min Servizio di Anatomia Patologica, Ospedale L. Sacco, Milano, Italy
Pages 390-395 | Published online: 06 Jul 2009

  • Puller CE, Williams GT. Gastrointestinal manifestations of type 1 neurofibromatosis (von Recklinghausen's disease). Histopathology 1991; 19: 1-11.
  • Hochberg FH, Dasilva AB, Galdabini J, et al. Gastrointestinal involvement in von Recklinghausen's neurofibromatosis. Neurology 1974; 24: 1144-51.
  • Bhattacharyya R, Jamieson GG. Recurrent perforation complicating intestinal neurofibromatosis. Aust N Z J Surg 1988; 58: 749-51.
  • Schaldenbrand JD, Appelman HD. Solitary solid stromal gastro-intestinal tumors in von Recklinghausen's disease with minimal smooth muscle differentiation. Hum Pathol 1984; 15: 229-32.
  • Akwari OE, Dozois RR, Weiland LH, et al. Leiomyosarcoma of the small and large bowel. Cancer 1978; 42: 1375-84.
  • Gennatas CS, Exarhakos G, Kondi-Pafiti A, et al. Malignant schwannoma of the stomach in a patient with neurofibromatosis. Eur J Surg Oncol 1988; 14: 261-4.
  • Sakaguchi N, Sano K, Ito M, et al. A case of von Recklinghausen's disease with bilateral pheochromocytoma-malignant peripheral nerve sheath tumors of the adrenal and gastrointestinal autonomie nerve tumors. Am J Surg Pathol 1996; 20: 889-97.
  • Walsh NMG, Bodurtha A. Auerbach's myenteric plexus. A possible site of origin for gastrointestinal stromal tumors in von Reck-linghausen's neurofibromatosis. Arch Pathol Lab Med 1990; 114: 522-5.
  • Langet DJ, Grotte DA, Batts KP. Multiple gastrointestinal tumors arising from the interstitial cells of Cajal (ICCs): a potential association with neurofibromatosis type I (NFI). Mod Pathol 1999; 12: 78A.
  • Kindblom LJ, Remotti HE, Angervall L, et al. Gastrointestinal pacemaker cell tumor: a manifestation of neurofibromatosis 1. Mod Pathol 1999; 12: 77A.
  • Min KW, Balaton AJ. Small intestinal stromal tumors with skeinoid fibers in neurofibromatosis: report of four cases with ultrastructural study of skeinoid fibers from paraffin blocks. Ultrastruct Pathol 1993; 17: 307-14.
  • Ishida T, Wada I, Horiuchi H, etal. Multiple small intestinal stromal tumors with skeinoid fibers in association with neurofibromatosis 1 (von Recklinghausen's disease). Pathol Int 1996; 46: 689-95.
  • McDonnel L. Skeinoid fibers. (Letter.) Am J Surg Pathol 1993; 17: 954-6.
  • Erlandson RA, Klimstra DS, Woodruff JM. Subclassification of gastrointestinal stromal tumors based on evaluation by electron microscopy and immunohistochemistry. Ultrastruct Pathol 1996; 20: 373-93.
  • Stumpf DA, Alksne JF, Annegers JF. Neurofibromatosis. NIH consensus development conference statement. Arch Neural 1988; 45: 575-8.
  • Min KW. Small intestinal stromal tumors with skeinoid fibers. Clinicopathological, immunohistochemical and ultrastructural investigations. Am J Surg Pathol 1992; 16: 145-55.
  • Riccardi WM. Von Recklinghausen neurofibromatosis. New Engl J Med 1981; 305: 1617-27.
  • Huson SM, Harper PS, Compston DAS. von Recklinghausen neurofi-bromatosis: a clinical and population study in South-East Wales. Brain 1988; 111: 1355-81.
  • Sircar K, Hewlett BR, Huizinga JD, et al. Interstitial cells of Cajal as precursors of gastrointestinal stromal tumors. Am J Surg Pathol 1999; 23: 377-89.
  • Kindblom LG, Remotti HE, Aldenborg F, et al. Gastrointestinal pacemaker cell tumor (GIPACT). Gastrointestinal stromal tumors show phenotypic characteristic of the interstitial cells of Cajal. Am J Pathol 1998; 152: 1259-69.
  • Miettinen M, Sarlomo-Rikala M, Lasota J. Gastrointestinal stromal tumors: recent advances in understanding of their biology. Hum Pathol 1999; 30: 1213-20.
  • Robinson TL, Sircar K, Hewlett BR, et al. Gastrointestinal stromal tumors may originate from a subset of CD34-positive interstitial cells of Cajal. Am J Pathol 2000; 156: 1157-63.
  • Sarlomo-Rikala M, Kovatich AJ, Barusevicius A, et al. CD117: a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34. Mod Pathol 1998; 11: 728-34.
  • Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science 1998; 279: 577-80.
  • Huizinga JD, Thuneberg L, Kluppel M, et al. W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 1995; 373: 347-9.
  • Tazawa K, Tsukada K, Makuuchi H, et al. An immunohistochemical and clinicopathological study of gastrointestinal stromal tumors. Pathol Ira 1999; 49: 786-98.
  • Rosai J. Small bowel, stromal tumors. In: Ackerman's surgical pathology. 8th ed. St Louis: Mosby-Year Book, 1996; 693.

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