Evaluation of the expression levels of nm23-H1 mRNA in primary breast cancer, benign breast disease, axillary lymph nodes and normal breast tissue

References

• Steeg, PS, Bevilacqua, G, Pozzatti, R, et al. Altered expression of NM23, a gene associated with low tumor metastatic potential, during adenovirus 2 Ela inhibition of experimental metastasis. Cancer Research 1988; 48: 6550–6554
   PubMed Web of Science ®Google Scholar
• Leone, A, McBride, OW, Weston, A, et al. Somatic allelic deletion of nm23 in human cancer. Cancer Research 1991; 51: 2490–2493
   PubMed Web of Science ®Google Scholar
• Liotta LA, Steeg PS. Clues to the function of nm23 and Awd proteins in development, signal transduction, and tumor metastasis provided by studies of Dictyostelium discoideum. J Natl Cancer Instit 1990; 81: 1170–1172
   Google Scholar
• Varesco, L, Caligo, MA, Simi, P, et al. The nm23 gene maps to human chromosome band 17q22 and shows a restriction fragment length polymorphism with BglII. Genes, Chromosomes and Cancer 1992; 4: 84–88
   PubMed Web of Science ®Google Scholar
• Stahl, JA, Leone, A, Rosengard, AM, et al. Identification of a second human nm23 gene, nm23-H2. Cancer Research 1991; 51: 445–449
   PubMed Web of Science ®Google Scholar
• Kimura N, Shimada N. Membrane-associated nucleoside diphosphate kinase from rat liver: Purification, characterization, and comparison with cytosolic enzyme. J Biolog Chem 1988; 263: 4647–4653
   PubMed Web of Science ®Google Scholar
• Wallet, V, Mutzel, R, Troll, H, et al. Dictyostelium nucleoside diphosphate kinase highly homologous to nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development. J Natl Cancer Instit 1990; 82: 1199–1203
   PubMed Web of Science ®Google Scholar
• Gilles, AM, Presecan, E, Vonica, A, et al. Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme. J Biolog Chem 1991; 266: 8784–8789
   PubMed Web of Science ®Google Scholar
• Rosengard, AM, Krutzsch, HC, Shearn, A, et al. Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development. Nature 1989; 342: 177–180
   PubMed Web of Science ®Google Scholar
• Biggs, J, Hersperger, E, Steeg, PS, et al. A Drosophila gene that is homologous to a mammalian gene associated with tumour metastasis codes for a nucleoside diphosphate kinase. Cell 1990; 63: 933–940
   PubMed Web of Science ®Google Scholar
• Agarwal RP, Robinson B, Parks RE, Jr. Nucleoside diphosphate kinase from human erythrocytes. Methods in Enzymology 1978; 51: 376–386
   PubMedGoogle Scholar
• Lacombe, ML, Wallet, V, Troll, H, et al. Functional cloning of a nucleoside diphosphate kinase from Dictyostelium discoideum. J Biolog Chem 1990; 265: 10012–10018
   PubMed Web of Science ®Google Scholar
• Ohtsuki K, Yokoyama M. Direct activation of guanine nucleotide binding proteins through a high-energy phosphate-transfer by nucleoside diphosphate-kinase. Biochem and Biophys Res Com 1987; 148: 300–307
   PubMed Web of Science ®Google Scholar
• Steeg, PS, Bevilacqua, G, Rosengard, AM, et al. Altered gene expression in tumour metastasis. The nm23 gene, V Schirrmacher, Schwartz-Albiez, R. Springer Verlag, Heidelberg 1989; 48–52, Cancer Metastasis
   Google Scholar
• Bevilacqua, G, Sobel, ME, Liotta, LA, et al. Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential. Cancer Research 1989; 49: 5185–5190
   PubMed Web of Science ®Google Scholar
• Hennessy, C, Henry, JA, May, FEB, et al. Expression of the antimetastatic gene nm23 in human breast cancer: An association with good prognosis. J Natl Cancer Instit 1991; 83: 281–285
   PubMed Web of Science ®Google Scholar
• Hirayama, R, Sawai, S, Takagi, Y, et al. Positive relationship between expression of anti-metastatic factor (nm23 gene product or nucleoside diphosphate kinase) and good prognosis in human breast cancer. J Natl Cancer Instit 1991; 83: 1249–1250
   PubMedGoogle Scholar
• Dawkins, HJS, Goodall, RJ, Hähnel, E, et al. nm23-H1 metastasis suppressor gene expression in primary breast cancer: Associations with axillary lymph node status, tumour size, type and grade. The Breast 1993; 2: 239–245
   Google Scholar
• Sastre-Garau, X, Lacombe, ML, Jouve, M, et al. Nucleoside diphosphate kinase/Nm23 expression in breast cancer: Lack of correlation with lymph node metastasis. Int J Cancer 1992; 50: 533–538
   PubMed Web of Science ®Google Scholar
• Haut, M, Steeg, PS, Willson, JKV, et al. Induction of nm23 gene expression in human colonic neoplasms and equal expression in colon tumours of lugh and low metastatic potential. J Natl Cancer Instit 1991; 83: 712–716
   PubMed Web of Science ®Google Scholar
• Myeroff LL, Markowitz SD. Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential. J Natl Cancer Instit 1993; 85: 147–152
   PubMed Web of Science ®Google Scholar
• Hailat, N, Keim, DR, Melhem, RF, et al. High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification. J Clin Invest 1991; 88: 341–345
   PubMed Web of Science ®Google Scholar
• Page DL, Anderson TJ. Diagnostic histopathology of the breast. Churchill Livingston. 1987
   Google Scholar
• Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience frome a large study with long-term follow-up. Histopathology 1991; 19: 403–410
   PubMed Web of Science ®Google Scholar
• Harvey JM, de Klerk NH, Sterrett GF. Histological grading in breast cancer: Interobserver agreement, and relation to other prognostic factors including ploidy. Pathology 1992; 24: 63–68
   PubMed Web of Science ®Google Scholar
• Hähnel, E, Joyce, R, Sterrett, G, et al. Detection of estradiol-induced messenger RNA (pS2) in uninvolved breast tissue from mastectomies for breast cancer. Breast Cancer Res Treat 1991; 20: 167–176
   Web of Science ®Google Scholar
• Chambon, P, Dierich, A, Gaub, M-P, et al. Promoter elements of genes coding for proteins and modulation of transcription by oestrogens and progesterone. Rec Prog Hormone Res 1984; 40: 1–42
   PubMedGoogle Scholar
• Spanakis E. Problems related to the interpretation of autoradiographic data on gene expression using common constitutive transcripts as controls. Nuc Acids Res 1993; 21: 3809–3819
   PubMed Web of Science ®Google Scholar
• Lacombe, ML, Sastre-Garaux, X, Lascu, I, et al. Overexpression of nucleoside diphosphate kinase (nm23) in solid tumours. Eur J Cancer 1991; 27: 1302–1307
   PubMed Web of Science ®Google Scholar