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Postgraduate Medicine Volume 36, 1964 - Issue 2
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Original Articles

Protein—Bound Iodine in Serum and Thyroidal Uptake of I131

Effect of Iodoalphionic, Iopanoic and Iophenoxic Acids

Donald E. RalstonMayo Clinic and Mayo Foundation, Rochester, Minnesota
, M.D.,
Thomas T. SchattenbergMayo Clinic and Mayo Foundation, Rochester, Minnesota
, M.D.,
Charles A. Owen Jr.Mayo Clinic and Mayo Foundation, Rochester, Minnesota
, M.D. &
William M. McConaheyMayo Clinic and Mayo Foundation, Rochester, Minnesota
, M.D.
Pages 141-148 | Published online: 18 Apr 2016

REFERENCES

  • Riggs, D. S., Gildea, E. F., Man, E. B. and Peters, J. P.: Blood iodine in patients with thyroid disease. J. Clin. Invest. 20: 345–353 (July) 1941.
  • Skanse, B.: Radioactive iodine in the diagnosis of thyroid disease. Acta med. scandinav., supp. 235, 136: 1–186, 1949.
  • Barker, S. B., Humphrey, M. J. and Soley, M. H.: The clinical determination of protein-bound iodine. J. Clin. Invest. 30: 55–62 (January) 1951.
  • Blackburn, C. M. and Power, M. H.: Diagnostic accuracy of serum protein-bound iodine determination in thyroid disease. J. Clin. Endocrinol. 15: 1379–1392 (November) 1955.
  • Owen, C. A., Jr.: Diagnostic Radioisotopes. Springfield, Illinois, Charles C Thomas, 1959.
  • Owen, C. A., Jr., McConahey, W. M., Keating, F. R., Jr. and Orvis, A. L.: Investigation of diseases of the thyroid gland by means of radioactive iodine. Fed. Proc. 14: 723–727 (September) 1955.
  • Bang, H. O. and Georg, J.: The elimination of pheniodol in normal subjects. Acta pharmacol. et toxicol. 7: 321–330, 1951.
  • Perlman, P. L., Kosinski, R. E. and Sutter, D.: Studies on the absorption and excretion of a new cholecystographic agent, Teridax. J. Am. Pharm. A. (Scient. Ed.) 44: 69–74 (February) 1955.
  • Schroder, J. S. and Rooney, D.: Excretion of 3- (3-amino-2,4,6-triiodopheny 1)-2-ethy 1-propanoic acid (Telepaque) by man. Proc. Soc. Exper. Biol. & Med. 83: 544–546 (July) 1953.
  • McChesney, E. W. and Hoppe, J. O.: Observations on the absorption and excretion of the glucuronide of iodopanoic acid by the cat. Arch, internat. pharmacodyn. 105: 306–312, 1950.
  • Man, E. B. and Peters, J. P.: Artifactual values of serum precipitable iodine. J. Lab. & Clin. Med. 35: 280–283, 1950.
  • Slingerland, D. W.: Effects of an organic iodine compound (Priodax) on tests of thyroid function. J. Clin. Endocrinol. 17: 82–93 (January) 1957.
  • Astwood, E. B.: Occurrence in sera of certain patients of large amounts of a newly isolated iodine compound. Tr. A. Am. Physicians 70: 183–191, 1957.
  • Shapiro, R. and Man, E. B.: Iophenoxic acid and serum-bound iodine values. J.A.M.A. 173: 1352 (July 23) 1960.
  • Shapiro, R.: The effect of maternal ingestion of iophenoxic acid on the serum protein-bound iodine of the progeny. New England J. Med. 264: 378–381 (February) 1961.
  • Hall, R. R. and Vanderlaan, W. P.: Transplacental transmission of “Teridax,” new cause of elevated PBI. Clin. Res. Proc. 9: 71 (January) 1961.
  • Raben, M. S.: Endocrine Conference, November 3, 1952, New England Center Hospital, Boston, Massachusetts. J. Clin. Endocrinol. 13: 469–472 (April) 1953.
  • Clark, R. E. and Shipley, R. A.: Thyroidal uptake of I131 after iopanoic acid (Telepaque) in 74 subjects. J. Clin. Endocrinol. 17: 1008–1010 (August) 1957.
  • Thorén, A.: The influence of iodide and iodized compounds on the PBI and the I131 tracer test with special reference to various biologic states of the thyroid. Acta endocrinol. 35: 351–358, 1960.

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