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Original Articles

Halothane Hepatitis

Current Concepts

, MD
Pages 65-70 | Published online: 07 Jul 2016

REFERENCES

  • Strunin L, Simpson BR: Halothane in Britain today. Br J Anaesth 44:919, 1972
  • Carney FM, Van Dyke RA: Halothane hepatitis. Anesth Analg (Cleve) 51:135, 1972
  • Klion FM, Schaffner F, Popper H: Hepatitis after exposure to halothane. Ann Intern Med 71:467, 1969
  • Sherlock S: Halothane hepatitis. Gut 12:324, 1971
  • Bunker JP, Child CG, Davidson CS, et al: Summary of the National Halothane Study. JAMA 197:775, 1966
  • Simpson BR, Strunin L, Walton B: Halothane hepatitis—fact or fallacy. Proc R Soc Med 66:56, 1973
  • Raventos J: The action of Fluothane. Br J Pharmacol 1:394, 1956
  • Stephen CR, Margolis G, Fabian LW, et al: Laboratory observations with Fluothane. Anesthesiology 19:770, 1958
  • Stevens WC, Egar ER, White A, et al: Comparative toxicity of halothane, diethyl ether, and isoflurane (forane) at subanesthetic concentrations in laboratory animals. Abstracts of Scientific Papers, 1972 American Society of Anesthesiologists Annual Meeting, Boston, 1972, p 239
  • Hughes HC Jr, Lang CM: Hepatic necrosis produced by repeated administration of halothane to guinea pigs. Anesthesiology 36:466, 1972
  • Bruce DL, Wingard DW: Anesthesia and the immune response. Anesthesiology 34:271–282, Mar 1971
  • Bruce DL: Halothane inhibition of phytohemag- glutinin-induced transformation of lymphocytes. Anesthesiology 36:201, 1972
  • Cullen BF, Sample WF, Chretien PB: The effect of halothane on phytohemagglutinin-induced transformation of human lymphocytes in vitro. Anesthesiology 36:206, 1972
  • Wingard DW: The in vivo effect of halothane on rat splenic lymphocytes. Anesth Anaig (Cleve) 52:73, 1973
  • Cullen BF, Hume RB, Chretien PB: The effects of anesthesia on phagocytosis and the reduction of nitroblue tetrazolium by human leukocytes. Abstracts of Scientific Papers, 1972 American Society of Anesthesiologists Annual Meeting, Boston, 1972, p 147
  • McCallum RW: Epidemiologic patterns of viral hepatitis. Am J Med 32:657, 1962
  • Kofi RS, Isselbacher KJ: Changing concepts in the epidemiology of viral hepatitis. N Engl J Med 278:1371, 1968
  • Dykes MH, Gilbert JP, Schurr PH, et al: Halothane and the liver. Can J Surg 15:217, 1972
  • Greene NM: Halothane anesthesia and hepatitis in a high-risk population. N Engl J Med 289:304, 1973
  • Rehder K, Forbes J, Alter H, et al: Halothane biotransformation in man. Anesthesiology 28:711, 1967
  • Geddes IC: Metabolism of volatile anesthetics. Br J Anaesth 44:953, 1972
  • Zimmerman HJ: The spectrum of hepatotoxicity. Perspect Biol Med 12:135, 1968
  • Brown BR Jr: Hepatic microsomal lipoperoxidation and inhalation anesthetics. Anesthesiology 36:458, 1972
  • Van Dyke RA: Biotransformation of volatile anaesthetics with special emphasis on the role of metabolism in the toxicity of anaesthetics. Can Anaesth Soc J 20:21, 1973
  • Carney FT: Mechanism of volatile anesthetic-induced hepatitis. Presented at Bernard H. Eliasberg memorial symposium on halothane hepatitis—fact or fallacy. Mount Sinai Hospital, New York, 1973
  • Belfrage S, Ahlgren I, Axelson S: Halothane hepatitis in an anesthetist. Lancet 2:1466, 1966
  • Klatskin G, Kimberg DV: Recurrent hepatitis attributable to halothane sensitization in an anesthetist. N Engl J Med 280:515, 1969
  • Paronetto F, Popper H: Lymphocyte stimulation induced by halothane in patients with hepatitis following exposure to halothane. N Engl J Med 283:277, 1970
  • Davies GE, Holmes JE: Drug-induced immunological effects on the liver. Br J Anaesth 44:941, 1972
  • Walton B, Dumonde DC, Williams C, et al: Lymphocyte transformation. JAMA 225:494, 1973
  • Sela M: Antigenicity: Some molecular aspects. Science 166:1365, 1969
  • Rosenberg PH, Wahlström T: Trifluoroacetic acid and some possible intermediate metabolites of halothane as haptens. Anesthesiology 38:224, 1973
  • Mathieu A, Di Padua D, Kahan B, et al: Lymphocyte transformation test, reaginic and complement fixing antibodies in guinea pigs sensitized to a metabolite of halothane and fluroxene. Anesth Analg (Cleve) 52:676, 1973
  • Reves JG, McCracken LE, Dowdy EG: Hepatic pathology in animals sensitized to a halothane metabolite and subsequently challenged with halothane. Abstracts of Scientific Papers, American Society of Anesthesiologists Annual Meeting, Washington, DC, 1974
  • Mathieu A, Galdabini JJ: Correlation between specific antibodies to a metabolite of halothane complexed to guinea pig albumin and hepatic lesions after multiple exposures. Fed Proc 33:625, 1974

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