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MEDICAL PRACTICE TODAY

Propranolol and lidocaine

Clinical use as antiarrhythmic agents

, MD & , MD
Pages 113-117 | Published online: 07 Jul 2016

References

  • Wit AL, Hoffman BF, Rosen MR: Electrophysiology and pharmacology of cardiac arrhythmias. IX. Cardiac electrophysiologic effects of beta adrenergic receptor stimulation and blockade. Part C. Am Heart J 90:795, 1975
  • Seides SF, Josephson ME, Batsford WP, et al: The electrophysiology of propranolol in man. Am Heart J 88:733, 1974
  • Gibson D, Sowton E: The use of beta-adrenergic receptor blocking drugs in dysrhythmias. Prog Cardio vase Dis 12:16, 1969
  • Singh BN, Jewitt DE: Beta-adrenergic receptor blocking drugs in cardiac arrhythmias. Drugs 7:426, 1974
  • Ibid,1 part B, P 665
  • Nies AS, Shand DG: Clinical pharmacology of propranolol. Circulation 52:6, 1975
  • Greenblatt DJ, Koch-Weser J: Adverse reactions to propranolol in hospitalized medical patients: A report from the Boston Collaborative Drug Surveillance Program. Am Heart J 86:478, 1973
  • Rosen MR, Merker C, Pippenger CE: The effects of lidocaine on the canine ECG and electrophysiologic properties of Purkinje fibers. Am Heart J 91:191, 1976
  • Rosen MR, Hoffman BF, Wit AL: Electrophysiology and pharmacology of cardiac arrhythmias. V. Cardiac antiarrhythmic effects of lidocaine. Am Heart J 89:526, 1975
  • Lie KI, Wellens HJ, van Capelle FJ, et al: Lidocaine in the prevention of primary ventricular fibrillation: A double-blind, randomized study of 212 consecutive patients. N Engl J Med 291:1324, 1974
  • Benowitz NL: Clinical applications of the pharmacokinetics of lidocaine. Cardiovasc Clin 6:77, 1974
  • Singh JB, Kocot SL: A controlled trial of intramuscular lidocaine in the prevention of premature ventricular contractions associated with acute myocardial infarction. Am Heart J 91:430, 1976
  • Valentine PA, Frew JL, Mashford ML, et al: Lidocaine in the prevention of sudden death in the pre-hospital phase of acute infarction: A double-blind study. N Engl J Med 291:1327, 1974
  • Thomson PD, Melmon KL, Richardson JA, et al: Lidocaine pharmacokinetics in advanced heart failure, liver disease, and renal failure in humans. Ann Intern Med 78:499, 1973
  • Collinsworth KA, Kaiman SM, Harrison DC: The clinical pharmacology of lidocaine as an antiarrhythmic drug. Circulation 50:1217, 1974

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