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REYE'S SYNDROME

Aspirin and Reye's syndrome

How strong an association?

Pages 47-54 | Published online: 07 Jul 2016

References

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  • Department of Health and Human Services, Food and Drug Administration,11 p 57892
  • Ibid, p 57885–901
  • Hoekelman RA. Take two aspirin and call me in the morning: salicylate use and Reye's syndrome. Am J Dis Child 1962: 136(11): 973–4
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  • McJunkin B. Barwick KW, Little WC. et al. Fatal massive hepatic necrosis following acetaminophen overdose. JAMA 1976: 236(16): 1874–5
  • Mitchell AA, Lovejoy FH Jr, Slone D. et al. Acetaminophen and aspirin: prescription, use, and accidental Ingestion among children. Am J Dis Child 1982: 136 (11): 976–9
  • American Academy of Pediatrics' Executive Board. AAP News Comment 1983: 34 (Mar): 1–3
  • American Academy of Pediatrics' Committee on Infectious Diseases. Aspirin and Reye syndrome. Pediatrics 1982: 69(6): 810–2
  • Lichtenstein PK, Heubi JE, Daugherty CC, et al. Grade I Reye's syndrome: a frequent cause of vomiting and liver dysfunction after varicella and upper-respiratory tract Infection. N Engl J Med 1983: 309(3): 133–9
  • You K. Salicylate and mitochondrial injury In Reye's syndrome. Science 1983: 221(4606): 163–5

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