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Clinical Features - Letter to the Editor

Statins and new onset of diabetes: which one outweighs risk or benefit?

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Page 146 | Received 31 Jul 2017, Accepted 23 Oct 2017, Published online: 30 Oct 2017

References

  • Yada T, Nakata M, Shiraishi T, et al. Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet beta-cells. Br J Pharmacol. 1999;126:1205–1213.
  • Sampson UK, Linton MF, Fazio S. Are statins diabetogenic? Curr Opin Cardiol. 2011 Jul;26(4):342–347.
  • Cederberg H, Stancakova A, Yaluri N, et al. Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort. Diabetologia. 2015;58:1109–1117.
  • Koh KK, Quon MJ, Han SH, et al. Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients. Atherosclerosis. 2009 Jun;204(2):483–490.
  • Koh KK, Quon MJ, Sakuma I, et al. Differential metabolic effects of rosuvastatin and pravastatin in hypercholesterolemic patients. Int J Cardiol. 2013 Jun 20;166(2):509–515.
  • Sattar N, Taskinen MR. Statins are diabetogenic – myth or reality? Atheroscler Suppl. 2012;13:1–10.

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