1,052
Views
7
CrossRef citations to date
0
Altmetric
Clinical Features - Letter to the Editor

An opposing point of view on the obesity paradox

&
Pages 333-334 | Received 08 Apr 2019, Accepted 24 Apr 2019, Published online: 06 May 2019

References

  • Hales CM, Fryar CD, Carroll MD, et al. Trends in obesity and severe obesity prevalence in US youth and adults by sex and age, 2007–2008 to 2015–2016. JAMA. 2018;319(16):1723–1725.
  • Kenchaiah S, Evans JC, Levy D, et al. Obesity and the risk of heart failure. N Engl J Med. 2002;347(5):305–313.
  • Look ARG, Wing RR, Bolin P, et al. Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes. N Engl J Med. 2013;369(2):145–154.
  • Look ARG, Gregg E, Jakicic J, et al. Association of the magnitude of weight loss and changes in physical fitness with long-term cardiovascular disease outcomes in overweight or obese people with type 2 diabetes: a post-hoc analysis of the look AHEAD randomised clinical trial. Lancet Diabetes Endocrinol. 2016;4(11):913–921.
  • American Diabetes Association. Prevention or delay of type 2 diabetes: standards of medical care in diabetes-2018. Diabetes Care. 2018;41(Suppl 1):S51–S54.
  • Lavie CJ, Ozemek C, Carbone S, et al. Sedentary behavior, exercise, and cardiovascular health. Circ Res. 2019;124(5):799–815.
  • Carbone S, Elagizi A, Lavie CJ The obesity paradox in cardiovascular diseases: current evidence and future perspectives. J Clin Exerc Physiol. 2018;8(1):30–40.
  • Carbone S, Lavie CJ, Arena R. Obesity and heart failure: focus on the obesity paradox. Mayo Clin Proc. 2017;92(2):266–279.
  • Chrysant SG, Chrysant GS. The single use of body mass index for the obesity paradox is misleading and should be used in conjunction with other obesity indices. Postgrad Med. 2019;131(2):96–102.
  • Lavie CJ, Laddu D, Arena R, et al. Healthy weight and obesity prevention: JACC health promotion series. J Am Coll Cardiol. 2018;72(13):1506–1531.
  • Carbone S, Popovic D, Lavie CJ, et al. Obesity, body composition and cardiorespiratory fitness in heart failure with preserved ejection fraction. Future Cardiol. 2017;13(5):451–463.
  • Ortega FB, Sui X, Lavie CJ, et al. Body mass index, the most widely used but also widely criticized index: would a criterion standard measure of total body fat be a better predictor of cardiovascular disease mortality? Mayo Clin Proc. 2016;91(4):443–455.
  • Padwal R, McAlister FA, McMurray JJ, et al. The obesity paradox in heart failure patients with preserved versus reduced ejection fraction: a meta-analysis of individual patient data. Int J Obes (Lond). 2014;38(8):1110–1114.
  • Clark AL, Fonarow GC, Horwich TB. Waist circumference, body mass index, and survival in systolic heart failure: the obesity paradox revisited. J Card Fail. 2011;17(5):374–380.
  • Khalid U, Ather S, Bavishi C, et al. Pre-morbid body mass index and mortality after incident heart failure: the ARIC study. J Am Coll Cardiol. 2014;64(25):2743–2749.
  • Lavie CJ, Cahalin LP, Chase P, et al. Impact of cardiorespiratory fitness on the obesity paradox in patients with heart failure. Mayo Clin Proc. 2013;88(3):251–258.
  • McAuley PA, Keteyian SJ, Brawner CA, et al. Exercise capacity and the obesity paradox in heart failure: the FIT (Henry ford exercise testing) project. Mayo Clin Proc. 2018;93(6):701–708.
  • Carbone S, Billingsley HE, Rodriguez-Miguelez P, et al. Lean mass abnormalities in heart failure: the role of sarcopenia, sarcopenic obesity and cachexia. Curr Probl Cardiol. 2019. DOI:10.1016/j.cpcardiol.2019.03.006. In press.
  • Kokkinos P, Faselis C, Franklin B, et al. Cardiorespiratory fitness, body mass index and heart failure incidence. Eur J Heart Fail. 2019;21:436–444.
  • McAuley PA, Artero EG, Sui X, et al. The obesity paradox, cardiorespiratory fitness, and coronary heart disease. Mayo Clin Proc. 2012;87(5):443–451.
  • De Schutter A, Kachur S, Lavie CJ, et al. The impact of inflammation on the obesity paradox in coronary heart disease. Int J Obes (Lond). 2016;40(11):1730–1735.
  • Carbone S, Lee PJ, Mauro AG, et al. Interleukin-18 mediates cardiac dysfunction induced by western diet independent of obesity and hyperglycemia in the mouse. Nutr Diabetes. 2017;7(4):e258.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.