200
Views
15
CrossRef citations to date
0
Altmetric
Clinical Features - Original Research

Usefulness of Triglyceride-glucose Index for estimating Hyperuricemia risk: Insights from a general Population

, , , &
Pages 348-356 | Received 21 Jan 2019, Accepted 24 May 2019, Published online: 03 Jun 2019

References

  • Bardin T, Richette P. Impact of comorbidities on gout and hyperuricaemia: an update on prevalence and treatment options. BMC Med. 2017 Jul 3;15(1):123. PubMed PMID: 28669352; PubMed Central PMCID: PMCPMC5494879. eng.
  • Borghi C, Rosei EA, Bardin T, et al. Serum uric acid and the risk of cardiovascular and renal disease. J Hypertens. 2015 Sep;33(9):1729–41; discussion 1741. PubMed PMID: 26136207; eng.
  • Zhao G, Huang L, Song M, et al. Baseline serum uric acid level as a predictor of cardiovascular disease related mortality and all-cause mortality: a meta-analysis of prospective studies. Atherosclerosis. 2013 Nov;231(1):61–68. PubMed PMID: 24125412; eng.
  • White J, Sofat R, Hemani G, et al. Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis. Lancet Diabetes Endocrinol. 2016 Apr;4(4):327–336. PubMed PMID: 26781229; PubMed Central PMCID: PMCPMC4805857. eng.
  • Mallat SG, Al Kattar S, Tanios BY, et al. Hyperuricemia, Hypertension, and Chronic Kidney Disease: an Emerging Association. Curr Hypertens Rep. 2016 Oct;18(10):74. PubMed PMID: 27696189; eng.
  • Cicero AFG, Fogacci F, Giovannini M, et al. Serum uric acid predicts incident metabolic syndrome in the elderly in an analysis of the Brisighella Heart Study. Sci Rep. 2018 Aug 1;8(1):11529. PubMed PMID: 30068918; PubMed Central PMCID: PMCPMC6070523. eng.
  • Cicero AFG, Fogacci F, Giovannini M, et al. Interaction between low-density lipoprotein-cholesterolaemia, serum uric level and incident hypertension: data from the Brisighella Heart Study. J Hypertens. 2019 Apr;37(4):728–731. PubMed PMID: 30817453; eng.
  • Li C, Hsieh MC, Chang SJ. Metabolic syndrome, diabetes, and hyperuricemia. Curr Opin Rheumatol. 2013 Mar;25(2):210–216. PubMed PMID: 23370374; eng.
  • Facchini F, Chen YD, Hollenbeck CB, et al. Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration. Jama. 1991 Dec 4;266(21):3008–3011. PubMed PMID: 1820474; eng.
  • Meshkani R, Zargari M, Larijani B. The relationship between uric acid and metabolic syndrome in normal glucose tolerance and normal fasting glucose subjects. Acta Diabetol. 2011 Mar;48(1):79–88. PubMed PMID: 21046418; eng.
  • Tsunoda S, Kamide K, Minami J, et al. Decreases in serum uric acid by amelioration of insulin resistance in overweight hypertensive patients: effect of a low-energy diet and an insulin-sensitizing agent. Am J Hypertens. 2002 Aug;15(8):697–701. PubMed PMID: 12160192; eng.
  • Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med. 2015 Nov 26;373(22):2117–2128. PubMed PMID: 26378978; eng.
  • Muscelli E, Natali A, Bianchi S, et al. Effect of insulin on renal sodium and uric acid handling in essential hypertension. Am J Hypertens. 1996 Aug;9(8):746–752. PubMed PMID: 8862220; eng.
  • Toyoki D, Shibata S, Kuribayashi-Okuma E, et al. Insulin stimulates uric acid reabsorption via regulating urate transporter 1 and ATP-binding cassette subfamily G member 2. Am J Physiol Renal Physiol. 2017 Sep 1;313(3):F826–f834. PubMed PMID: 28679589; eng.
  • Khosla UM, Zharikov S, Finch JL, et al. Hyperuricemia induces endothelial dysfunction. Kidney Int. 2005 May;67(5):1739–1742. PubMed PMID: 15840020; eng.
  • Roy D, Perreault M, Marette A. Insulin stimulation of glucose uptake in skeletal muscles and adipose tissues in vivo is NO dependent. A J Physiol. 1998 Apr;274(4 Pt 1):E692–9. PubMed PMID: 9575831; eng.
  • Ewang-Emukowhate M, Perera D, Wierzbicki A. Dyslipidaemia related to insulin resistance and cardiovascular disease in South Asian and West African populations. Curr Pharm Des. 2014;20(40):6270–6275.
  • Sparks JD, Sparks CE, Adeli K. Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2104–2112. PubMed PMID: 22796579.
  • Mikhail N. The metabolic syndrome: insulin resistance. Curr Hypertens Rep. 2009 Apr;11(2):156–158. PubMed PMID: 19278606; eng.
  • Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005 Apr 16–22;365(9468):1415–1428. PubMed PMID: 15836891; eng.
  • Ferrannini E, Barrett EJ, Bevilacqua S, et al. Effect of fatty acids on glucose production and utilization in man. J Clin Invest. 1983 Nov;72(5):1737–1747. PubMed PMID: 6138367; PubMed Central PMCID: PMCPMC370462. eng.
  • Stringer DM, Zahradka P, Taylor CG. Glucose transporters: cellular links to hyperglycemia in insulin resistance and diabetes. Nutr Rev. 2015 Mar;73(3):140–154. PubMed PMID: 26024537; eng.
  • Yki-Jarvinen H. Glucose toxicity. Endocr Rev. 1992 Aug;13(3):415–431. PubMed PMID: 1425483; eng.
  • Shannon C, Merovci A, Xiong J, et al. Effect of chronic hyperglycemia on glucose metabolism in subjects with normal glucose tolerance. Diabetes. 2018 Sep 13;67:2507–2517. PubMed PMID: 30213826; eng.
  • Hoy AJ, Bruce CR, Cederberg A, et al. Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation. Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1358–64. PubMed PMID: 17785505; eng.
  • Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat Disord. 2008;6(4):299–304.
  • Sanchez-Inigo L, Navarro-Gonzalez D, Fernandez-Montero A, et al. The TyG index may predict the development of cardiovascular events. Eur J Clin Invest. 2016 Feb;46(2):189–197. PubMed PMID: 26683265.
  • Navarro-Gonzalez D, Sanchez-Inigo L, Pastrana-Delgado J, et al. Triglyceride-glucose index (TyG index) in comparison with fasting plasma glucose improved diabetes prediction in patients with normal fasting glucose: the Vascular-Metabolic CUN cohort. Prev Med. 2016 May;86:99–105. PubMed PMID: 26854766.
  • Zheng R, Mao Y. Triglyceride and glucose (TyG) index as a predictor of incident hypertension: a 9-year longitudinal population-based study. Lipids Health Dis. 2017;16:1.
  • Levey A, Stevens L, Schmid C, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604–612.
  • Liu R, Han C, Wu D, et al. Prevalence of hyperuricemia and gout in mainland China from 2000 to 2014: a systematic review and meta-analysis. Biomed Res Int. 2015;2015:762820. PubMed PMID: 26640795; PubMed Central PMCID: PMCPMC4657091. eng.
  • Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care. 1997 Jul;20(7): 1183–1197. PubMed PMID: 9203460; eng.
  • Simental-Mendia LE, Hernandez-Ronquillo G, Gomez-Diaz R, et al. The triglycerides and glucose index is associated with cardiovascular risk factors in normal-weight children and adolescents. Pediatr Res. 2017 Dec;82(6):920–925. PubMed PMID: 28853725.
  • Guerrero-Romero F, Simental-Mendia LE, Gonzalez-Ortiz M, et al. The product of triglycerides and glucose, a simple measure of insulin sensitivity. Comparison with the euglycemic-hyperinsulinemic clamp. J Clin Endocrinol Metab. 2010 Jul;95(7):3347–3351. PubMed PMID: 20484475.
  • Vasques ACJ, Novaes FS, de Oliveira M, et al. TyG index performs better than HOMA in a Brazilian population: A hyperglycemic clamp validated study. Diabetes Res Clin Pract. 2011;93(3):e98–e100.
  • Cook NR. Use and misuse of the receiver operating characteristic curve in risk prediction. Circulation. 2007;115(7):928–935.
  • Pickering JW, Endre ZH. New metrics for assessing diagnostic potential of candidate biomarkers. Clin J Am Soc Nephrol. 2012 Aug;7(8):1355–1364. PubMed PMID: 22679181.
  • Pencina M, D’Agostino R, Steyerberg E. Extensions of net reclassification improvement calculations to measure usefulness of new biomarkers. Stat Med. 2011;30(1):11–21.
  • Pencina MJ, D’ Agostino RB, D’ Agostino RB, et al. Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond. Stat Med. 2008;27(2):157–172.
  • Grunkemeier GL, Jin R. Net reclassification index: measuring the incremental value of adding a new risk factor to an existing risk model. Ann Thorac Surg. 2015 Feb;99(2):388–392. PubMed PMID: 25639389.
  • Mazidi M, Katsiki N, Mikhailidis DP, et al. The link between insulin resistance parameters and serum uric acid is mediated by adiposity. Atherosclerosis. 2018 Mar;270:180–186. PubMed PMID: 29459295; eng.
  • DeLany JP, Dube JJ, Standley RA, et al. Racial differences in peripheral insulin sensitivity and mitochondrial capacity in the absence of obesity. J Clin Endocrinol Metab. 2014 Nov;99(11):4307–4314. PubMed PMID: 25105736; PubMed Central PMCID: PMCPMC4223429. eng.
  • Chang SH, Yu YC, Carlsson NP, et al. Racial disparity in life expectancies and life years lost associated with multiple obesity-related chronic conditions. Obesity (Silver Spring, Md). 2017 May;25(5):950–957. PubMed PMID: 28329429; PubMed Central PMCID: PMCPMC5404943. eng.
  • Zhu Y, Pandya BJ, Choi HK. Prevalence of gout and hyperuricemia in the US general population: the National Health and Nutrition Examination Survey 2007–2008. Arthritis Rheumatism. 2011 Oct;63(10):3136–3141. PubMed PMID: 21800283; eng.
  • Wu J, Qiu L, Cheng XQ, et al. Hyperuricemia and clustering of cardiovascular risk factors in the Chinese adult population. Sci Rep. 2017 Jul 14;7(1):5456. PubMed PMID: 28710367; PubMed Central PMCID: PMCPMC5511152. eng.
  • Veronese N, Stubbs B, Trevisan C, et al. Results of an observational cohort study of hyperuricemia as a predictor of poor physical performance in the elderly. Arthritis Care Res (Hoboken). 2017 Aug;69(8):1238–1244. PubMed PMID: 27723277; eng.
  • Yamada A, Sato KK, Kinuhata S, et al. Association of visceral fat and liver fat with hyperuricemia. Arthritis Care Res (Hoboken). 2016 Apr;68(4):553–561. PubMed PMID: 26414410; eng.
  • Zhang Y, Qiu H. Dietary magnesium intake and hyperuricemia among US adults. Nutrients. 2018 Mar 2;10(3). PubMed PMID: 29498657; PubMed Central PMCID: PMCPMC5872714. eng. DOI: 10.3390/nu10030296.
  • Liu FZ, Liao HT, Lin WD, et al. Predictive effect of hyperuricemia on left atrial stasis in non-valvular atrial fibrillation patients. Int J Cardiol. 2018 May 1;258:103–108. PubMed PMID: 29467096; eng.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.