Admittances characteristics by sepsis in the Spanish internal medicine services between 2005 and 2015: mortality pattern

References

• Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801.
   PubMed Web of Science ®Google Scholar
• Lo R, Leung L, Brabrand M, et al. qSOFA is a poor predictor of short-term mortality in all patients: a systematic review of 410,000 patients. J Clin Med. 2019;8(1):61.
   PubMed Web of Science ®Google Scholar
• Iñigo J, Sendra JM, Díaz R, et al. Epidemiología y costes de la sepsis grave en Madrid: estudio de altas hospitalarias. Med Intensiva. 2006;30(5):197–203.
   PubMedGoogle Scholar
• Dellinger RP, Levy MM, Carlet JM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock. Crit Care Med. 2008;36(1):296–327.
   PubMed Web of Science ®Google Scholar
• Meyer N, Harhay MO, Small DS, et al. Temporal trends in incidence, sepsis-related mortality, and hospital-based acute care after sepsis. Crit Care Med. 2018;46(3):354–360.
   PubMed Web of Science ®Google Scholar
• Çıldır E, Bulut M, Akalın H, et al. Evaluation of the modified MEDS, MEWS score and Charlson comorbidity index in patients with community acquired sepsis in the emergency department. Intern Emerg Med. 2012;8(3):255–260.
   PubMed Web of Science ®Google Scholar
• Stevenson EK, Rubenstein AR, Radin GT, et al. Two decades of mortality trends among patients with severe sepsis. Crit Care Med. 2014;42(3):625–631.
   PubMed Web of Science ®Google Scholar
• Fleischmann-Struzek C, Mikolajetz A, Schwarzkopf D, et al. Challenges in assessing the burden of sepsis and understanding the inequalities of sepsis outcomes between national health systems: secular trends in sepsis and infection incidence and mortality in Germany. Intensive Care Med. 2018;44(11):1826–1835.
   PubMed Web of Science ®Google Scholar
• Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chron Dis. 1987;40(5):373–383.
   PubMedGoogle Scholar
• Rhee C, Dantes R, Epstein L, et al. Incidence and trends of sepsis in US hospitals using clinical vs claims data, 2009-2014. JAMA. 2017;318(13):1241.
   PubMed Web of Science ®Google Scholar
• Deyo R, Cherkin D, Ciol M. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45(6):613–619.
   PubMed Web of Science ®Google Scholar
• Rhee C, Murphy MV, Li L, et al. Comparison of trends in sepsis incidence and coding using administrative claims versus objective clinical data. Clinl Infect Dis. 2014;60(1):88–95.
   PubMed Web of Science ®Google Scholar
• Rhee C, Kadri S, Huang SS, et al. Objective sepsis surveillance using electronic clinical data. Infect Control Hosp Epidemiol. 2015;37(02):163–171.
   PubMed Web of Science ®Google Scholar
• Kadri SS, Rhee C, Strich JR, et al. Estimating ten-year trends in septic shock incidence and mortality in United States academic medical centers using clinical data. Chest. 2017;151(2):278–285.
   PubMed Web of Science ®Google Scholar
• Angus DC, Linde-Zwirble WT, Lidicker J, et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001;29(7):1303–1310.
   PubMed Web of Science ®Google Scholar
• Bernal Sobrino JL, Diaz Manglano J, Marco Martinez J, et al. Ocho años de hospitalización en las Unidades de Medicina Interna (2007–2014). ¿Qué ha cambiado? Rev Clin Esp (Barc). 2017;217(8):446–453.
   PubMed Web of Science ®Google Scholar
• Ely EW, Angus DC, Williams MD, et al. Drotrecogin alfa (Activated) treatment of older patients with severe sepsis. Clinl Infect Dis. 2003;37(2):187–195.
   PubMed Web of Science ®Google Scholar
• Rajagopalan S, Yoshikawa TT. Antimicrobial therapy in the elderly. Med Clin North Am. 2001;85(1):133–147.
   PubMed Web of Science ®Google Scholar
• Valenti WM, Trudell RG, Bentley DW. Factors predisposing to oropharyngeal colonization with gram-negative bacilli in the aged. N Engl J Med. 1978;298(20):1108–1111.
   PubMed Web of Science ®Google Scholar
• Jensen GL, McGee M, Binkley J. Nutrition in the elderly. Gastroenterol Clin North Am. 2001;30(2):313–334.
   PubMed Web of Science ®Google Scholar
• Martin GS, Mannino DM, Moss M. The effect of age on the development and outcome of adult sepsis. Crit Care Med. 2006;34(1):15–21.
   PubMed Web of Science ®Google Scholar
• Nicolle LE. Infection control in long-term care facilities. Clin Infect Dis. 2000;31(3):752–756.
   PubMed Web of Science ®Google Scholar
• Bouza C, Martínez-Alés G, López-Cuadrado T. The impact of dementia on hospital outcomes for elderly patients with sepsis: A population-based study. PLoS One. 2019;142:e0212196. Published 2019 Feb 19.
   PubMed Web of Science ®Google Scholar
• Montero A, Hervás A, Morera R, et al. Control de síntomas crónicos: efectos secundarios del tratamiento con Radioterapia y Quimioterapia. Oncología (Barc). 2005;28(3):41–50.
   Google Scholar
• Barba R, Marco J, Ruiz J, et al. The obesity paradox in stroke: impact on mortality and short-term readmission. J Stroke Cerebrovasc Dis. 2015;24(4):766–770.
   PubMed Web of Science ®Google Scholar
• Zapatero A, Barba R, Ruiz J, et al. Malnutrition and obesity: influence in mortality and readmissions in chronic obstructive pulmonary disease patients. J Hum Nutr Diet. 2013;26(Suppl 1):16–22.
   PubMed Web of Science ®Google Scholar
• Arabi YM, Dara SI, Tamim HM, et al., Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group. Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study. Crit Care. 2013;17:R72. .
   PubMed Web of Science ®Google Scholar
• Trivedi V, Bavishi C, Jean R. Impact of obesity on sepsis mortality: A systematic review. J Crit Care. 2015;303:518–524. Epub 2014 Dec 17.
   PubMed Web of Science ®Google Scholar
• Pepper DJ, Sun J, Welsh J, et al. Increased body mass index and adjusted mortality in ICU patients with sepsis or septic shock: a systematic review and meta-analysis. Crit Care. 2016;20(1):181.
   PubMed Web of Science ®Google Scholar
• Kadri SS, Rhee C, Strich J, et al. Estimating ten-year trends in septic shock incidence and mortality in United States academic medical centers using clinical data. Chest. 2017;151(2):278–285.
   PubMed Web of Science ®Google Scholar