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Clinical focus: Cardiovascular Disease - Original Research

Awareness, treatment rates, and compliance to treatment in patients with serum LDL cholesterol higher than 250 mg/dL, and possible, probable, or definite familial hypercholesterolemia

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Pages 146-153 | Received 02 Jun 2020, Accepted 31 Jul 2020, Published online: 23 Sep 2020

References

  • Soutar AK, Naoumova RP. Mechanism of disease: genetic causes of familial hypercholesterolemia. Nat Clin Pract Cardiovasc Med. 2007;4:214–225.
  • Hovingh GK, Davidson MH, Kastelein JJP, et al. Diagnosis and treatment of familial hypercholesterolemia. Eur Heart J. 2013;34:962–971.
  • Kavey RE, Allada V, Daniels SR, et al. American Heart Association Expert Panel on Population and Prevention Science; American Heart Association Council on Cardiovascular Disease in the Young; American Heart Association Council on Epidemiology and Prevention; American Heart Association Council on Nutrition, Physical Activity and Metabolism; American Heart Association Council on High Blood Pressure Research; American Heart Association Council on Cardiovascular Nursing; American Heart Association Council on the Kidney in Heart Disease; Interdisciplinary Working Group on Quality of Care and Outcomes Research. Cardiovascular risk reduction in high-risk pediatric patients: a scientific statement from the American Heart Association Expert Panel on Population and Prevention Science; the Councils on Cardiovascular Disease in the Young, Epidemiology and Prevention, Nutrition, Physical Actvity and Metabolism, High Blood Pressure Research, Cardiovascular Nursing, and the Kidney in Heart Disease; and Interdisciplinary Working Group on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics. Circulation. 2006;114((24.):2710–2738.
  • Civeria F. Guidelines for the diagnosis and management of heterozygous familial hypercholesterolemia. Atherosclerosis. 2004;173:55–68.
  • Williams RR, Hunt SC, Schumacher MC, et al. Diagnosis heterozygous familial hypercholesterolemia using new practical criteria validated by molecular genetics. Am J Cardiol. 1993;72:171–176.
  • Scientific Steering Committee on behalf of the Simon Broome Register Group. Risk of fatal coronary heart disease in familial hypercholesterolemia. BMJ. 1991;303(6807):893–896. DOI: 10.1136/bmj.303.6807.893.
  • Nordestgaard BG, Chapman MJ, Humphries SE, et al. European Atherosclerosis Society Consensus Panel: familial Consensus Statement of the European Atherosclerosis Society. Hypercholesterolemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease. Eur Heart J. 2013;34(45):3478–3490.
  • Safarova MS, Liu H, Kullo IJ. Rapid identification of familial hypercholesterolemia from electronic health records: the SEARCH study. J Clin Lipidol. 2016;10(5):1230–1239.
  • Ahmad ZS, Andersen RL, Andersen LH, et al. US physician practices for diagnosing familial hypercholesterolemia: data from the CASCADE-FH registry. J Clin Lipidol. 2016;10(5):1223–1229.
  • Neil HA, Hammond T, Huxley R, et al. Extent of underdiagnosis of familial hypercholesterolaemia in routine practice: prospective registry study. BMJ. 2000;321(7254):148.
  • deGoma EM, Ahmad ZS, O’Brien EC, et al. Treatment gaps in adults with heterozygous familial hypercholesterolemia in the United States data from the CASCADE-FH registry. Circ Cardiovasc Genet. 2016;9:240–249.
  • Brunham LR, Cermakova L, Lee T, et al. Contemporary trends in the management and outcomes of patients with familial hypercholesterolemia in Canada: a prospective observational study. Can J Cardiol. 2017;33:385–392.
  • Bucholz EM, Rodday AM, Kolor K, et al. Prevalence and predictors of cholesterol screening, awareness, and statin treatment among US adults with familial hypercholesterolemia or other forms of severe dyslipidemia (1999-2014). Circulation. 2018;137(21):2218–2230.
  • Batais MA, Almigbal TH, Abdulhak AAB, et al. Assessment of physicians’ awareness and knowledge of familial hypercholesterolemia in Saudi Arabia: is there a gap? PLoS ONE. 2017;12(8):e0183494.
  • Bell DA, Garton-Smith J, Vickery A, et al. Familial hypercholesterolaemia in primary care: knowledge and practices among general practitioners in Western Australia. Heart Lung Circ. 2014;23(4):309–313. .
  • Rangarajan N, Balasubramanian S, Pang J, et al. Knowledge and awareness of familial hypercholesterolaemia among registered medical practitioners in Tamil Nadu: are they suboptimal? J Clin Diagn Res. 2016;10(5):OC52–56.
  • Kwok S, Pang J, Adam S, et al. An online questionnaire survey of UK general practitioners’ knowledge and management of familial hypercholesterolaemia. BMJ Open. 2016;6(11):e012691.
  • Benn M, Watts GF, Tybjaerg-Hansen A, et al. Familial hypercholesterolemia in the Danish general population: prevalence, coronary artery disease, and cholesterol-lowering medication. J Clin Endocrinol Metab. 2012;97(11):3956–3964.
  • Besseling J, Sjouke B, Kastelein JJ. Screening and treatment of familial hypercholesterolemia - Lessons from the past and opportunities for the future (based on the Anitschkow Lecture 2014). Atherosclerosis. 2015;241(2):597–606.
  • Turkey Family Structure Research Findings, Recommendations. T. C. Ministry of Family and Social Policies. Research and Social Policy Series 07. Türkiye Aile Yapısı Araştırması Tespitler, Öneriler. T.C. Aile ve Sosyal Politikalar Bakanlığı. Araştırma ve Sosyal Politika Serisi 07. İstanbul: Çizge Tanıtım ve Kırtasiye Ltd. Şti. Birinci Basım; 2014. ISBN: 978-605-4628-55-1. .[cited 2020 Mar 23]. Available from: https://ailevecalisma.gov.tr
  • Haymana C, Berlik H, Güneş Y, et al. Identifying undiagnosed or undertreated patients with familial hypercholesterolemia from the laboratory records of a tertiary medical center. Turk Kardiyol Dern Ars. 2017;45(8):731–738.
  • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285:2486–2497.
  • Relationship of atherosclerosis in young men to serum lipoprotein cholesterol concentrations and smoking. A preliminary report from the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group. JAMA. 1990;264:3018–3024.
  • Nanchen D, Gencer B, Muller O, et al. Prognosis of patients with familial hypercholesterolemia after acute coronary syndromes. Circulation. 2016;134(10):698–709.
  • Onat A, Senocak M, Surdum-Avcı G, et al. Prevalence of disease in population with low cholesterol levels. Int J Cardiol coronary heart disease in Turkish adults. Int J Cardiol. 1993;39:23–31.
  • Satman I, Omer B, Tutuncu Y, et al. TURDEP-II Study Group. Twelve-year trends in the prevalence and risk factors of diabetes and prediabetes in Turkish adults. Eur J Epidemiol. 2013;28(2):169–180.
  • International Diabetes Federation. Diabetes Atlas. 8th ed. 2017. cited 2020 Mar 23]. Available from: http://www.diabetesatlas.org/resources/2017-atlas.html
  • Umans-Eckenhausen MA, Defesche JC, Sijbrands EJ, et al. Review of first 5 years of screening for familial hypercholesterolaemia in the Netherlands. Lancet. 2001;357:165–168.
  • Humphries SE, Norbury G, Leigh S, et al. What is the clinical utility of DNA testing in patients with familial hypercholesterolaemia? Curr Opin Lipidol. 2008;19:362–368.
  • Bhatnagar D, Morgan J, Siddiq S, et al. Outcome of case finding among relatives of patients with known heterozygous familial hypercholesterolaemia. BMJ. 2000;321:1497–1500.

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