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Postgraduate Medicine Volume 133, 2021 - Issue 2
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Clinical focus: Cardiovascular disease -Editorial

Dentists and physicians’ practices meet once again: Potential unfavorable clinical effects of frequent mouthwash use

Jim Zhongning Chena Sciences Department of Internal Medicine, University of Arkansas, Little Rock, AR, USAView further author information
,
Kaumudi J. Joshipurab Center for Clinical Research and Health Promotion, University of Puerto Rico, Rio Piedras, Puerto RicoView further author information
,
Fuad Habashc Medical Sciences and Cardiology Division, University of Arkansas, Little Rock, AR, USAView further author information
&
Angel Lopez-Candalesc Medical Sciences and Cardiology Division, University of Arkansas, Little Rock, AR, USACorrespondence[email protected].
View further author information
Pages 123-124 | Received 15 Aug 2020, Accepted 25 Sep 2020, Published online: 19 Oct 2020

References

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  • Lundberg J, Weitzberg E, Gladwin M. The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov. 2008;7:156–167.
  • Senkus KE, Crowe-White KM. Influence of mouth rinse use on the enterosalivary pathway and blood pressure regulation: a systematic review. Crit Rev Food Sci Nutr. 2019Sep;23:1–13.
  • [cited 2020 Sep 24]. Available from: https://www.ada.org/en/member-center/oral-health-topics/mouthrinse.
  • Joshipura KJ, Muñoz-Torres FJ, Morou-Bermudez E, et al. Over-the-counter mouthwash use and risk of pre-diabetes/diabetes. Nitric Oxide - Biol Chem. 2017;71:14–20.
  • Joshipura K, Muñoz-Torres F, Fernández-Santiago J, et al. Over-the-counter mouthwash use, nitric oxide and hypertension risk. Blood Press. 2020;29(2):103–112.
  • Bryan NS, Tribble G, Angelov N. Oral microbiome and nitric oxide: the missing link in the management of blood pressure. Curr Hypertens Rep. 2017 Apr;19(4):33. PMID: 28353075.
  • Goh CE, Trinh P, Colombo PC, et al. Association between nitrate‐reducing oral bacteria and cardiometabolic outcomes: results from ORIGINS. J Am Heart Assoc. 2019 Dec 3;8(23):e013324.

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