558
Views
8
CrossRef citations to date
0
Altmetric
Clinical features - Review

Association between alopecia areata and thyroid dysfunction

ORCID Icon &
Pages 895-898 | Received 23 May 2021, Accepted 27 Aug 2021, Published online: 06 Sep 2021

References

  • Ebel B. The papyrus ebers: the greatest Egyptian document. Copenhagen: Leivin and Munksgaard; 1937.
  • Wasserman D, Guzman-Sanchez DA, Scott D, et al. Alopecia areata. Int J Dermatol. 2007;46:121–131.
  • Pratt CH, King LE Jr, Messenger AG, Christiano AM, Sundberg JP. Alopecia areata. Nat Rev Dis Primers. 2017;3:17011. Published 2017 Mar 16. doi:https://doi.org/10.1038/nrdp.2017.11
  • Gilhar A, Etzioni A, Paus R. Alopecia areata. N EnglJ Med. 2012;366:1515–1525.
  • Friedman PS. Alopecia areata and autoimmunity. Br J Dermatol. 1969;81(105):153–157.
  • Puavilai S, Puavilai G, Charuwichitratana S, et al. Prevalence of thyroid diseases in patients with alopecia areata. Int J Dermatol. 1994;33:632–633.
  • Lewinski A, Broniarczyk-Dyla G, Sewerynek E, et al. Abnormalities in structure and function of the thyroid gland in patients with alopecia areata. J Am Acad Dermatol. 1990;23(4 Pt 1):768–769.
  • Thomas EA, Kadyan RS. Alopecia areata and autoimmunity: a clinical study. Indian J Dermatol. 2008;53:70–74.
  • Conic R, Tamashunas N, Damiani G, et al. Comorbidities in pediatric alopecia areata. J Eur Acad Dermatol Venereol. 2020;34:2898–2901.
  • Forouzan P, Cohen PR. Systemic lupus erythematosus presenting as alopecia areata. Cureus. 2020 Jun 20;12(6):e8724.
  • Conic RRZ, Chu S, Tamashunas, et al. Prevalence of cardiac and metabolic diseases among patients with alopecia areata. J Eur Acad Dermatol Venereol. 2021;35(2):e128–e129.
  • Klonowska B, Charemska D, Zelazowska-Rutkowska B, et al. Does Hashimoto’s Thyroiditis Increase the Risk of Cardiovascular Disease in Young Type 1 Diabetic Patients?. Autoimmune Thyroid Pathology-Specificity of the Pediatric Age. 2021;11: 431
  • Cappola AR, Desai AS, Medici M, et al. Thyroid and cardiovascular disease: research agenda for enhancing knowledge, prevention, and treatment. Circulation. 2019 Jun 18;139(25):2892–909
  • Dos Santos Garrett NFM, da Costa ACC, Damiani GQ, et al. Patients with lung cancer undergoing immune checkpoint inhibitors: a meta-analysis of dermatological toxicities. Crit Rev Oncol Hematol. 2020;152:102983.
  • Mitchel AJ, Krull EA. Alopecia areata: pathogenesis and treatment. J Am Acad Dermatol. 1984;11:763–775.
  • Strazzula LC, Wang EHC, Avila L, et al. Alopecia areata: disease characteristics, clinical evaluation, and new perspective on pathogenesis. J Am Acad Dermatol. 2018;78:1.
  • Stankler L. Synchronous alopecia areata is two siblings: a possible viral etiology. Lancet. 2002;29:85.
  • McElwee KJ, Gilhar A, Tobin DJ, et al. What causes alopecia areata? Exp Dermatol. 2013;22:609–626.
  • Hordinsky MK. Overview of alopecia areata. J Investig Dermatol Symp Proc. 2013;16:13–15.
  • Islam N, Leung PS, Huntley AC, et al. The autoimmune basis of alopecia areata: a comprehensive review. Autoimmun Rev. 2015;14:81–89.
  • Tobin DJ, Orentreich N, Fenton DA, et al. Antibodies to hair follicles in alopecia areata. J Investig Dermatol. 1994;102:721–724.
  • Tobin JD. Characterization of hair follicle antigens targeted by the anti-hair follicle immune response. J Investig Dermatol Symp Proc. 2003;8:176–181.
  • Amirnia M, Mahmoudi S, Karkon-Shayan F, et al. Comparative study of intralesional steroid injection and cryotherapy in alopecia areata. Niger Med J. 2015;56:249–252.
  • Gilhar A, Landau M, Assy B, et al. Melanocyte-associated T cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on Prkdcscid mice. J Invest Dermatol. 2001;117:1357–1362.
  • Gilhar A, Kalish RS. Alopecia areata: a tissue specific autoimmune disease of the hair follicle. Autoimmun Rev. 2006;5:64‑9.
  • Misery L, Sannier K, Chastaing M, et al. Treatment of alopecia areata with sulfasalazine. J Eur Acad Dermatol Venereol. 2007;21:547‑8.
  • Bui K, Polisetty S, Gilchrist H, et al. Successful treatment of alopecia universalis with alefacept: a case report and review of the literature. Cutis. 2008;81:431‑4.
  • Balevi Ş. Alopecia areata. Turk Klin J Int Med Sci. 2006;2:158.
  • Kasumagic-Halilovic E. Thyroid autoimmunity in patients with alopecia areata. Acta Dermatoveneral Croat. 2008;16:123–125.
  • Seyrafi H, Akhiani M, Abbassi H, et al. Evaluation of the profile of alopecia and the prevalence of thyroid function test abnormalities and serum autoantibodies in Iranian patients. BMC Dermatol. 2005;5:11.
  • Bakry OA, Basha MA, Shafiee MKE, et al. Thyroid disorders with alopecia areata in Egyptian patients. Indian J Dermatol. 2014;59:49–55.
  • Thomas EA, Kadyan RS. Alopecia areata and autoimmunity: a clinical study. Indian J Dermatol. 2008;53:70–74.
  • Park SM, Oh YJ, Lew BL, et al. The association between thyroid dysfunction, thyroid autoimmunity,and clinical features of alopecia areata: a retrospective study. J Am Acad Dermatol. 2018 May 9.Doi: https://doi.org/10.1016/j.jaad.2018.04.051. [Epub ahead of print].
  • Lee S, Lee YB, Kim BJ, et al. Screening of thyroid function and autoantibodies in patients with alopecia areata: a systematic review and metaanalysis. J Am Acad Dermatol. 2018;80:1410–1413.e4.
  • Saylam Kurtipek G, Cihan FG, Ş ED, et al. The frequency of autoimmune thyroid disease in alopecia areata and vitiligo patients. Biomed Res Int. 2015;2015:435947.
  • Rahnama Z, Farajzadeh S, Mohamamdi S, et al. Prevalence of thyroid disorders in patients with alopecia areata. J Pak Assoc Dermatol. 2016;24:246–250.
  • Kaur G, Kuldeep CM, Bhargava P, et al. Insignificant correlation between thyroid hormone and anti-thyroid peroxidase antibodies in alopecia areata patients in Northern Rajasthan. Int J Trichology. 2017;9:149–153.
  • Gönül M, Ü G, Pişkin E, et al. Alopesi areatali hastaların geriye dönük değerlendirilmesi. Turkish J Dermatol. 2011;5:43–47.
  • Jabbour SA. Cutaneous manifestations of endocrine disorders: a guide for dermatologists. Am J Clin Dermatol. 2003;4:315–331.
  • Tan E, Tay YK, Goh CL, et al. The pattern and profile of alopecia areata in Singapore-a study of 219 Asians. Int J Dermatol. 2002;41:748–753.
  • Yang Z, Yang X, Jin X. Association analysis between alopecia areata and thyroid autoimmunity in adults. Chin J Dermatol. 2015;48:697–699.
  • Díaz-Angulo S, Lopez-Hoyos M, Muñoz-Cacho P, et al. High prevalence of thyroid autoimmunity in patients with alopecia areata and vitiligo: a controlled study. Australas J Dermatol. 2015;56:142–143.
  • Thomas EA, Kadyan RS. Alopecia areata and autoimmunity: a clinical study. Indian J Dermatol. 2008;53:70–74.
  • Huang KP, Mullangi S, Guo Y. Autoimmune, atopic, and mental health comorbid conditions associated with alopecia areata in the United States. JAMA Dermatol. 2013;149:789.
  • Burman KD, McKinley-Grant L. Dermatologic aspects of thyroid disease. Clin Dermatol. 2006;24:247–255.
  • Roos A, Links TP. de Jong-van Den Berg LTW. Thyroid peroxidase antibodies, levels of thyroid stimulating hormone and development of hypothyroidism in euthyroid subjects. Eur J Internal Med. 2010;21:555–559.
  • Prummel MF, Wiersinga WM. Thyroid peroxidase autoantibodies in euthyroid subjects. Best Pract Res ClinEndocrinol Metab. 2005;19:1–15.
  • Suditu G, Preda C, Vulpoi C, et al. Endocrinological disorders in association with alopecia areata‑a 27 patients study. Rev Med Chir SocMed Nat Iasi. 2001;105:533‑5.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.