Perceptions and knowledge gaps on CHA₂DS₂-VASc score components: a joint survey of Chinese clinicians and clinical pharmacists

References

• Benjamin EJ, Muntner P, Alonso A, et al. Heart disease and stroke statistics-2019 update: a report from the American Heart Association. Circulation. 2019 Mar 5;139(10):e56–e528. PubMed PMID: 30700139.
   PubMed Web of Science ®Google Scholar
• Alkhouli M, Friedman PA. Ischemic stroke risk in patients with nonvalvular atrial fibrillation: JACC review topic of the week. J Am Coll Cardiol. 2019 Dec 17;74(24):3050–3065. PubMed PMID: 31865973.
   PubMed Web of Science ®Google Scholar
• Chen LY, Chung MK, Allen LA, et al. Atrial fibrillation burden: moving beyond atrial fibrillation as a binary entity: a scientific statement from the American Heart Association. Circulation. 2018 May 15;137(20):e623–e644. PubMed PMID: 29661944.
   PubMed Web of Science ®Google Scholar
• Lip GY, Frison L, Halperin JL, et al. Identifying patients at high risk for stroke despite anticoagulation: a comparison of contemporary stroke risk stratification schemes in an anticoagulated atrial fibrillation cohort. Stroke. 2010 Dec;41(12):2731–2738. PubMed PMID: 20966417.
   PubMed Web of Science ®Google Scholar
• Gage BF, Waterman AD, Shannon W, et al. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001 Jun 13;285(22):2864–2870. PubMed PMID: 11401607.
   PubMed Web of Science ®Google Scholar
• Chen JY, Zhang AD, Lu HY, et al. CHADS2 versus CHA2DS2-VASc score in assessing the stroke and thromboembolism risk stratification in patients with atrial fibrillation: a systematic review and meta-analysis. J Geriatr Cardiol. 2013 Sep;10(3):258–266. PubMed PMID: 24133514; PubMed Central PMCID: PMCPMC3796700.
   PubMedGoogle Scholar
• Olesen JB, Torp-Pedersen C, Hansen ML, et al. The value of the CHA2DS2-VASc score for refining stroke risk stratification in patients with atrial fibrillation with a CHADS2 score 0-1: a nationwide cohort study. Thromb Haemost. 2012 Jun;107(6):1172–1179. PubMed PMID: 22473219.
   PubMed Web of Science ®Google Scholar
• Van Staa TP, Setakis E, Di Tanna GL, et al. A comparison of risk stratification schemes for stroke in 79,884 atrial fibrillation patients in general practice. J Thromb Haemost. 2011 Jan 9;(1):39–48. PubMed PMID: 21029359. DOI:https://doi.org/10.1111/j.1538-7836.2010.04085.x.
   PubMed Web of Science ®Google Scholar
• Hindricks G, Potpara T, Dagres N, et al. ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2021 Feb 1;42(5):373–498. PubMed PMID: 32860505.
   PubMed Web of Science ®Google Scholar
• January CT, Wann LS, Calkins H, et al. AHA/ACC/HRS focused update of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on clinical practice guidelines and the heart rhythm society in collaboration with the society of thoracic surgeons. Circulation. 2019 Jul 9;140(2):e125–e151. PubMed PMID: 30686041.
   PubMed Web of Science ®Google Scholar
• Yoon M, Yang PS, Jang E, et al. Dynamic changes of CHA2DS2-VASc score and the risk of ischaemic stroke in asian patients with atrial fibrillation: a Nationwide Cohort Study. Thromb Haemost. 2018 Jul;118(7):1296–1304. PubMed PMID: 29723875.
   PubMed Web of Science ®Google Scholar
• Heidbuchel H, Dagres N, Antz M, et al. Major knowledge gaps and system barriers to guideline implementation among European physicians treating patients with atrial fibrillation: a European Society of Cardiology international educational needs assessment. Europace. 2018 Dec 1;20(12):1919–1928. PubMed PMID: 29538637.
   PubMed Web of Science ®Google Scholar
• Zhang J, Lenarczyk R, Marin F, et al. The interpretation of CHA2DS2-VASc score components in clinical practice: a joint survey by the European Heart Rhythm Association (EHRA) scientific initiatives committee, the EHRA young electrophysiologists, the association of cardiovascular nursing and allied professionals, and the European Society of cardiology council on stroke. Europace. 2021 Feb 5;23(2):314–322. PubMed PMID: 33554259.
   PubMed Web of Science ®Google Scholar
• Chang SS, Dong JZ, Ma CS, et al. Current status and time trends of oral anticoagulation use among Chinese Patients with nonvalvular atrial fibrillation: the Chinese Atrial Fibrillation Registry Study. Stroke. 2016 Jul;47(7):1803–1810. PubMed PMID: 27283198.
   PubMed Web of Science ®Google Scholar
• Chinese Medical Association. Guideline for rational medication of atrial fibrillation in primary care. Chin J Gener Pract. 2021;20(2):166–174.
   Google Scholar
• Zhang S, Yang YM, Huang CX, et al. Guideline of stroke prevention in Chinese patients with atrial fibrillation (2017). Chin J Cardiac Arrhythmias. 2018;22(1):17–30.
   Google Scholar
• Chong DT, Andreotti F, Verhamme P, et al. Direct oral anticoagulants in asian patients with atrial fibrillation: consensus recommendations by the Asian Pacific Society of cardiology on strategies for thrombotic and bleeding risk management. Eur Cardiol. 2021 Feb;16:e23. PubMed PMID: 34135993; PubMed Central PMCID: PMCPMC8201470.
   PubMed Web of Science ®Google Scholar
• Ponikowski P, Voors AA, Anker SD, et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC)Developed with the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J. 2016 Jul 14;37(27):2129–2200. PubMed PMID: 27206819.
   PubMed Web of Science ®Google Scholar
• Zhang C, Wang N, Shen NN, et al. Net clinical benefit of antithrombotic therapy in patients with heart failure and sinus rhythm: a network meta-analysis from 5 clinical trials. Thromb Res. 2020 Jun;190:122–128. PubMed PMID: 32361051.
   PubMed Web of Science ®Google Scholar
• Banerjee A, Taillandier S, Olesen JB, et al. Ejection fraction and outcomes in patients with atrial fibrillation and heart failure: the Loire Valley Atrial Fibrillation Project. Eur J Heart Fail. 2012 Mar;14(3):295–301. PubMed PMID: 22294759.
   PubMed Web of Science ®Google Scholar
• Jung H, Yang PS, Jang E, et al. Effectiveness and safety of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation with hypertrophic cardiomyopathy: a Nationwide Cohort Study. Chest. 2019 Feb;155(2):354–363. PubMed PMID: 30472021.
   PubMed Web of Science ®Google Scholar
• Noseworthy PA, Yao X, Shah ND, et al. Stroke and bleeding risks in NOAC- and warfarin-treated patients with hypertrophic cardiomyopathy and atrial fibrillation. J Am Coll Cardiol. 2016 Jun 28;67(25):3020–3021. PubMed PMID: 27339501.
   PubMed Web of Science ®Google Scholar
• Guttmann OP, Rahman MS, O’Mahony C, et al. Atrial fibrillation and thromboembolism in patients with hypertrophic cardiomyopathy: systematic review. Heart. 2014 Mar;100(6):465–472. PubMed PMID: 24014282.
   PubMed Web of Science ®Google Scholar
• Pisters R, Lane DA, Marin F, et al. Stroke and thromboembolism in atrial fibrillation. Circ J. 2012;76(10):2289–2304. PubMed PMID: 23001018.
   PubMed Web of Science ®Google Scholar
• Marinigh R, Lip GY, Fiotti N, et al. Age as a risk factor for stroke in atrial fibrillation patients: implications for thromboprophylaxis. J Am Coll Cardiol. 2010 Sep 7;56(11):827–837. PubMed PMID: 20813280.
   PubMed Web of Science ®Google Scholar
• Lip GY, Clementy N, Pericart L, et al. Stroke and major bleeding risk in elderly patients aged >/=75 years with atrial fibrillation: the Loire Valley atrial fibrillation project. Stroke. 2015 Jan;46(1):143–150. PubMed PMID: 25424474.
   PubMed Web of Science ®Google Scholar
• Overvad TF, Skjoth F, Lip GY, et al. Duration of diabetes mellitus and risk of thromboembolism and bleeding in atrial fibrillation: Nationwide Cohort Study. Stroke. 2015 Aug;46(8):2168–2174. PubMed PMID: 26152296.
   PubMed Web of Science ®Google Scholar
• Fe U, Jackson LR 2nd, Thomas KL. Atrial fibrillation and diabetes mellitus: can we modify stroke risk through glycemic control? Circ Arrhythm Electrophysiol. 2019 May;12(5):e007351. PubMed PMID: 30995870.
   PubMed Web of Science ®Google Scholar
• Chao TF, Liu CJ, Liao JN, et al. Use of oral anticoagulants for stroke prevention in patients with atrial fibrillation who have a history of intracranial hemorrhage. Circulation. 2016 Apr 19;133(16):1540–1547. PubMed PMID: 26969761.
   PubMed Web of Science ®Google Scholar
• Bronnum Nielsen P, Larsen TB, Gorst-Rasmussen A, et al. Intracranial hemorrhage and subsequent ischemic stroke in patients with atrial fibrillation: a nationwide cohort study. Chest. 2015 Jun;147(6):1651–1658. PubMed PMID: 25412369.
   PubMed Web of Science ®Google Scholar
• Nielsen PB, Skjoth F, Overvad TF, et al. Female sex is a risk modifier rather than a risk factor for stroke in atrial fibrillation: should we use a CHA2DS2-VA score rather than CHA2DS2-VASc? Circulation. 2018 Feb 20;137(8):832–840. PubMed PMID: 29459469.
   PubMed Web of Science ®Google Scholar