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Clinical Focus: Multimodal Analgesia - Original research

The descending pain modulation system predicts short term efficacy of multimodal pain therapy: an observational prospective cohort study

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Pages 277-287 | Received 26 Jul 2021, Accepted 02 Dec 2021, Published online: 05 Jan 2022

References

  • De Felice M, Sanoja R, Wang R, et al. Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain. Pain. 2011;152(12):2701–2709.
  • Li W, Gong Y, Liu J, et al. Peripheral and central pathological mechanisms of chronic low back pain: a narrative review. J Pain Res. 2021;14:1483–1494.
  • Nahman-Averbuch H, Shefi T, Schneider VJ, et al. Quantitative sensory testing in patients with migraine: a systematic review and meta-analysis. Pain. 2018;159(7):1202–1223.
  • Potvin S, Marchand S. Pain facilitation and pain inhibition during conditioned pain modulation in fibromyalgia and in healthy controls. Pain. 2016;157(8):1704–1710.
  • Zabala Mata J, Lascurain-Aguirrebeña I, Dominguez López E, et al. Enhanced pronociceptive and disrupted antinociceptive mechanisms in nonspecific chronic neck pain. Phys Ther. 2021 pzaa223; 101(3): DOI:https://doi.org/10.1093/ptj/pzaa223
  • McPhee ME, Vaegter HB, Graven-Nielsen T. Alterations in pronociceptive and antinociceptive mechanisms in patients with low back pain: a systematic review with meta-analysis. Pain. 2020;161(3):464–475.
  • Neelapala YVR, Bhagat M, Frey-Law L. Conditioned pain modulation in chronic low back pain: a systematic review of literature. Clin J Pain. 2020;36(2):135–141.
  • Moreira LPC, Mendoza C, Barone M, et al. Reduction in pain inhibitory modulation and cognitive-behavioral changes in patients with chronic low back pain: a case-control study. Pain Manag Nurs. 2021;22(5):S1524-9042(21)00152–1.
  • Pas R, Rheel E, Van Oosterwijck S, et al. Endogenous pain modulation in children with functional abdominal pain disorders. Pain. 2019;160(8):1883–1890.
  • Gagné M, Côté I, Boulet M, et al. Conditioned pain modulation decreases over time in patients with neuropathic pain following a spinal cord injury. Neurorehabil Neural Repair. 2020;34(11):997–1008.
  • Ossipov MH, Dussor GO, Porreca F. Central modulation of pain. J Clin Invest. 2010;120(11):3779–3787.
  • Braun M, Bello C, Riva T, et al. Quantitative sensory testing to predict postoperative pain. Curr Pain Headache Rep. 2021;25(1):3.
  • Larsen DB, Laursen M, Edwards RR, et al. The combination of preoperative pain, conditioned pain modulation, and pain catastrophizing predicts postoperative pain 12 months after total knee arthroplasty. Pain Med. 2021;22(7):1583–1590. pnaa402.
  • Petersen KK, Vaegter HB, Stubhaug A, et al. The predictive value of quantitative sensory testing: a systematic review on chronic postoperative pain and the analgesic effect of pharmacological therapies in patients with chronic pain. Pain. 2021;162(1):31–44.
  • Naugle KM, Carey C, Evans E, et al. The role of deficient pain modulatory systems in the development of persistent post-traumatic headaches following mild traumatic brain injury: an exploratory longitudinal study. J Headache Pain. 2020;21(1):138.
  • Edwards RR, Dolman AJ, Martel MO, et al. Variability in conditioned pain modulation predicts response to NSAID treatment in patients with knee osteoarthritis. BMC Musculoskelet Disord. 2016;17(1):284.
  • Petersen KK, Simonsen O, Olesen AE, et al. Pain inhibitory mechanisms and response to weak analgesics in patients with knee osteoarthritis. Eur J Pain. 2019;23(10):1904–1912.
  • Niesters M, Proto PL, Aarts L, et al. Tapentadol potentiates descending pain inhibition in chronic pain patients with diabetic polyneuropathy. Br J Anaesth. 2014;113(1):148–156.
  • Yarnitsky D, Granot M, Nahman-Averbuch H, et al. Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy. Pain. 2012;153(6):1193–1198.
  • Nahman-Averbuch H, Schneider VJ, Chamberlin LA, et al. Identification of neural and psychophysical predictors of headache reduction after cognitive behavioral therapy in adolescents with migraine. Pain. 2021;162(2):372–381.
  • Morris MC, Bruehl S, Stone AL, et al. Does quantitative sensory testing improve prediction of chronic pain trajectories? A longitudinal study of youth with functional abdominal pain participating in a randomized controlled trial of cognitive behavioral treatment. Clin J Pain. 2021;37(9):648–656.
  • Arzneimittelkommission Der Deutschen Ärzteschaft (AkdÄ), Bundespsychotherapeutenkammer (BPtK), Bundesverband Selbstständiger Physiotherapeuten (IFK), et al. Nationale VersorgungsLeitlinie Nicht-spezifischer Kreuzschmerz – langfassung, 2. Auflage [Internet]. Bundesärztekammer (BÄK); Kassenärztliche Bundesvereinigung (KBV); Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF). 2017 [cited 2021 Jul 22]. Available from: http://www.leitlinien.de/mdb/downloads/nvl/kreuzschmerz/kreuzschmerz-2aufl-vers1-lang.pdf
  • Schlereth T. Diagnose und nicht interventionelle Therapie neuropathischer Schmerzen, S2k-Leitlinie, 2019 [Internet]. Deutsche Gesellschaft für Neurologie (Hrsg.), Leitlinien für Diagnostik und Therapie in der Neurologie. [cited 2021 Jan 29]. Available from: https://dgn.org/leitlinien/ll-030-114-diagnose-und-nicht-interventionelle-therapie-neuropathischer-schmerzen-2019
  • Arnold B, Brinkschmidt T, Casser H-R, et al. [Multimodal pain therapy: principles and indications]. Schmerz. 2009;23(2):112–120.
  • Akyuz G, Kenis O. Physical therapy modalities and rehabilitation techniques in the management of neuropathic pain. Am J Phys Med Rehabil. 2014;93(3):253–259.
  • Burns AS, Delparte JJ, Ballantyne EC, et al. Evaluation of an interdisciplinary program for chronic pain after spinal cord injury. PM R. 2013;5(10):832–838.
  • Norrbrink Budh C, Kowalski J, Lundeberg T. A comprehensive pain management programme comprising educational, cognitive and behavioural interventions for neuropathic pain following spinal cord injury. J Rehabil Med. 2006;38(3):172–180.
  • Deckert S, Kaiser U, Kopkow C, et al. A systematic review of the outcomes reported in multimodal pain therapy for chronic pain. Eur J Pain. 2016;20(1):51–63.
  • Langenmaier A-M, Amelung VE, Karst M, et al. Subgroups in chronic low back pain patients - a step toward cluster-based, tailored treatment in inpatient standard care: on the need for precise targeting of treatment for chronic low back pain. Ger Med Sci. 2019;17:Doc09.
  • Gehling J, Mainka T, Vollert J, et al. Short-term test-retest-reliability of conditioned pain modulation using the cold-heat-pain method in healthy subjects and its correlation to parameters of standardized quantitative sensory testing. BMC Neurol. 2016;16(1):125.
  • Rolke R, Baron R, Maier C, et al. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values. Pain. 2006;123(3):231–243.
  • Magerl W, Krumova EK, Baron R, et al. Reference data for quantitative sensory testing (QST): refined stratification for age and a novel method for statistical comparison of group data. Pain. 2010;151(3):598–605.
  • Pfau DB, Geber C, Birklein F, et al. Quantitative sensory testing of neuropathic pain patients: potential mechanistic and therapeutic implications. Curr Pain Headache Rep. 2012;16(3):199–206.
  • Fruhstorfer H. Thermal sensibility changes during ischemic nerve block. Pain. 1984;20(4):355–361.
  • Yarnitsky D, Sprecher E, Zaslansky R, et al. Heat pain thresholds: normative data and repeatability. Pain. 1995;60(3):329–332.
  • Freynhagen R, Baron R, Gockel U, et al. Pain DETECT: a new screening questionnaire to identify neuropathic components in patients with back pain. Curr Med Res Opin. 2006;22(10):1911–1920.
  • Freynhagen R, Tölle TR, Gockel U, et al. The painDETECT project - far more than a screening tool on neuropathic pain. Curr Med Res Opin. 2016;32(6):1033–1057.
  • Ware J, Kosinski M, Keller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34(3):220–233.
  • Halme AS, Tannenbaum C. Performance of a Bayesian approach for imputing missing data on the SF-12 health-related quality-of-life measure. Value Health. 2018;21(12):1406–1412.
  • Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–370.
  • Stewart A, Ware JE. Measuring functioning and well-being: the medical outcomes study approach. 1991 [cited 2021 Jul 7]. Available from: https://www.rand.org/pubs/commercial_books/CB361.html
  • Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale(N.J): L. Erlbaum Associates; 1988.
  • LaMotte RH, Thalhammer JG, Torebjörk HE, et al. Peripheral neural mechanisms of cutaneous hyperalgesia following mild injury by heat. J Neurosci. 1982;2(6):765–781.
  • Treede RD, Meyer RA, Raja SN, et al. Peripheral and central mechanisms of cutaneous hyperalgesia. Prog Neurobiol. 1992;38(4):397–421.
  • Maier C, Baron R, Tölle TR, et al. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes. Pain. 2010;150(3):439–450.
  • Pieh C, Altmeppen J, Neumeier S, et al. Gender differences in response to CBT-orientated multimodal treatment in depressed patients with chronic pain. Psychiatr Prax. 2012;39(6):280–285.
  • Pieh C, Altmeppen J, Neumeier S, et al. Gender differences in outcomes of a multimodal pain management program. Pain. 2012;153(1):197–202.
  • Eskander JP, Beakley BD, Zhang S, et al. A multimodal approach to pain management for patients with chronic back pain: outcome measures at 1 year. Curr Pain Headache Rep. 2019;23(8):54.
  • Muhsen A, Moss P, Gibson W, et al. The Association Between Conditioned Pain Modulation and Manipulation-induced Analgesia in People With Lateral Epicondylalgia. Clin J Pain. 2019;35(5):435–442.
  • Smith A, Ritchie C, Warren J, et al. Exercise-induced hypoalgesia is impaired in chronic Whiplash-associated Disorders (WAD) with both aerobic and isometric exercise. Clin J Pain. 2020;36(8):601–611.
  • Sugimine S, Saito S, Araki T, et al. Endogenous analgesic effect of pregabalin: a double-blind and randomized controlled trial. Eur J Pain. 2017;21(6):997–1006.
  • Meeus M, Ickmans K, Struyf F, et al. Does acetaminophen activate endogenous pain inhibition in chronic fatigue syndrome/Fibromyalgia and rheumatoid arthritis? A double-blind randomized controlled cross-over trial. Pain Physician. 2013;16(2;3):E61–70.
  • Kosek E, Ordeberg G. Lack of pressure pain modulation by heterotopic noxious conditioning stimulation in patients with painful osteoarthritis before, but not following, surgical pain relief. Pain. 2000;88(1):69–78.
  • Graven-Nielsen T, Wodehouse T, Langford RM, et al. Normalization of widespread hyperesthesia and facilitated spatial summation of deep-tissue pain in knee osteoarthritis patients after knee replacement. Arthritis Rheum. 2012;64(9):2907–2916.
  • Imai Y, Petersen KK, Mørch CD, et al. Comparing test-retest reliability and magnitude of conditioned pain modulation using different combinations of test and conditioning stimuli. Somatosens Mot Res. 2016;33(3–4):169–177.
  • Yarnitsky D, Bouhassira D, Drewes AM, et al. Recommendations on practice of conditioned pain modulation (CPM) testing. Eur J Pain. 2015;19(6):805–806.
  • Moont R, Pud D, Sprecher E, et al. “Pain inhibits pain” mechanisms: is pain modulation simply due to distraction? Pain. 2010;150(1):113–120.

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