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COVID-19

Acute COVID-19 in unvaccinated children without a history of previous infection during the delta and omicron periods

ORCID Icon, ORCID Icon & ORCID Icon
Pages 727-733 | Received 25 Mar 2023, Accepted 07 Aug 2023, Published online: 21 Aug 2023

References

  • World Health Organization. Tracking SARS-CoV-2 variants. https://wwwwhoint/activities/tracking-SARS-CoV-2-variants. 2023.
  • Chung E, Chow EJ, Wilcox NC, et al. Comparison of symptoms and RNA levels in children and adults with SARS-CoV-2 infection in the community setting. JAMA Pediatr. 2021;175(10):e212025. doi: 10.1001/jamapediatrics.2021.2025
  • Iuliano AD, Brunkard JM, Boehmer TK, et al. Trends in disease severity and Health care utilization during the early Omicron variant period compared with previous SARS-CoV-2 high transmission periods - United States, December 2020-January 2022. MMWR Morb Mortal Wkly Rep. 2022;71(4):146–152. doi: 10.15585/mmwr.mm7104e4
  • Ryu B, Shin E, Kim NY, et al. Severity of COVID-19 associated with SARS-CoV-2 variants circulating in the Republic of Korea. Public Health Weekly Report. 2022;15(47):2873–2895. doi: 10.56786/PHWR.2022.15.47.2873
  • Butt AA, Dargham SR, Loka S, et al. Coronavirus disease 2019 disease severity in children infected with the Omicron variant. Clin Infect Dis. 2022;75(1):e361–e7. doi: 10.1093/cid/ciac275
  • Tagarro A, Coya ON, Perez-Villena A, et al. Features of COVID-19 in children during the Omicron wave compared with previous waves in Madrid, Spain. Pediatr Infect Dis J. 2022;41(5):e249–e51. doi: 10.1097/INF.0000000000003482
  • Relan P, Motaze NV, Kothari K, et al. Severity and outcomes of Omicron variant of SARS-CoV-2 compared to Delta variant and severity of Omicron sublineages: a systematic review and metanalysis. BMJ Glob Health. 2023;8(7):e012328. doi: 10.1136/bmjgh-2023-012328
  • Esper FP, Adhikari TM, Tu ZJ, et al. Alpha to Omicron: disease severity and clinical outcomes of major SARS-CoV-2 variants. J Infect Dis. 2023;227(3):344–352. doi: 10.1093/infdis/jiac411
  • Khemiri H, Ayouni K, Triki H, et al. SARS-CoV-2 infection in pediatric population before and during the Delta (B.1.617.2) and Omicron (B.1.1.529) variants era. Virol J. 2022;19(1):144. doi: 10.1186/s12985-022-01873-4
  • Choi SH, Choi JH, Lee JK, et al. Clinical characteristics and outcomes of children with SARS-CoV-2 infection during the Delta and Omicron variant-dominant periods in Korea. J Korean Med Sci. 2023;38(9):e65. doi: 10.3346/jkms.2023.38.e65
  • Han MS, Kim KM, Oh KJ, et al. Distinct clinical and Laboratory Features of COVID-19 in children during the pre-Delta, Delta and Omicron Wave. Pediatr Infect Dis J. 2023;42(5):423–428. doi: 10.1097/INF.0000000000003872
  • Jang EJ, Choe YJ, Choe SA, et al. Presumed population immunity to SARS-CoV-2 in South Korea, April 2022. Osong Public Health Res Perspect. 2022;13(5):377–381. doi: 10.24171/j.phrp.2022.0209
  • World Health Organization. Clinical management of COVID-19: living guideline. World Health Organization. 2023; 2023 (WHO/2019-nCoV/clinical/2023.1).
  • Han SB, Rhim JW, Kang JH, et al. Clinical features and outcomes of influenza by virus type/subtype/lineage in pediatric patients. Transl Pediatr. 2021;10(1):54–63. doi: 10.21037/tp-20-196
  • Tso WWY, Kwan MYW, Wang YL, et al. Severity of SARS-CoV-2 Omicron BA.2 infection in unvaccinated hospitalized children: comparison to influenza and parainfluenza infections. Emerg Microbes Infect. 2022;11(1):1742–1750. doi: 10.1080/22221751.2022.2093135
  • Choi YY, Choi SH, Choi JH, et al. SARS-CoV-2-Naive Korean children and Adolescents hospitalized with COVID-19 in 2021. J Korean Med Sci. 2022;37(42):e303. doi: 10.3346/jkms.2022.37.e303
  • Shoji K, Akiyama T, Tsuzuki S, et al. Clinical characteristics of COVID-19 in hospitalized children during the Omicron variant predominant period. J Infect Chemother. 2022;28(11):1531–1535. doi: 10.1016/j.jiac.2022.08.004
  • Cohen R, Rybak A, Ouldali N, et al. From the original SARS-CoV-2 strain to the Omicron variant: Predictors of COVID-19 in ambulatory symptomatic children. Infect Dis Now. 2022;52(8):432–440. doi: 10.1016/j.idnow.2022.09.012
  • Vihta KD, Pouwels KB, Peto TE, et al. Omicron-associated changes in SARS-CoV-2 symptoms in the United Kingdom. Clin Infect Dis. 2022. doi: 10.1093/cid/ciac613
  • Iijima H, Kubota M, Ogimi C. Change in Seizure incidence in febrile children with COVID-19 in the era of Omicron variant of Concern. J Pediatric Infect Dis Soc. 2022;11(11):514–517. doi: 10.1093/jpids/piac085
  • Thongsing A, Eizadkhah D, Fields C, et al. Provoked seizures and status epilepticus in a pediatric population with COVID-19 disease. Epilepsia. 2022;63(8):e86–e91. doi: 10.1111/epi.17293
  • Pascarella A, Maglione M, Lenta S, et al. Seizures in children with SARS-CoV-2 infection: Epidemiological, clinical and Neurophysiologi-cal Characterization. Children (Basel). 2022;9(12):1923. doi: 10.3390/children9121923
  • Kim JM, Park EG, Lee JY, et al. Characteristics of febrile seizures with SARS-CoV-2 infection in the Omicron era. Transl Pediatr. 2023;12(5):807–815. doi: 10.21037/tp-22-579
  • Lefchak B, Nickel A, Lammers S, et al. Analysis of COVID-19-Related croup and SARS-CoV-2 variant Predominance in the US. JAMA Netw Open. 2022;5(7):e2220060. doi: 10.1001/jamanetworkopen.2022.20060
  • Choi YY, Kim YS, Lee SY, et al. Croup as a Manifestation of SARS-CoV-2 Omicron variant infection in Young children. J Korean Med Sci. 2022;37(20):e140. doi: 10.3346/jkms.2022.37.e140
  • Hui KPY, Ng KC, JCW H, et al. Replication of SARS-CoV-2 Omicron BA.2 variant in ex vivo cultures of the human upper and lower respiratory tract. EBioMedicine. 2022;83:104232. doi: 10.1016/j.ebiom.2022.104232
  • Whitaker M, Elliott J, Bodinier B, et al. Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England. Nat Commun. 2022;13(1):6856. doi: 10.1038/s41467-022-34244-2
  • Edward PR, Lorenzo-Redondo R, Reyna ME, et al. Severity of Illness caused by severe acute respiratory syndrome coronavirus 2 variants of Concern in children: A Single-Center retrospective Cohort study. J Pediatric Infect Dis Soc. 2022;11(10):440–447. doi: 10.1093/jpids/piac068
  • Quintero AM, Eisner M, Sayegh R, et al. Differences in SARS-CoV-2 clinical manifestations and disease severity in children and Adolescents by Infecting variant. Emerg Infect Dis. 2022;28(11):2270–2280. doi: 10.3201/eid2811.220577
  • Han JY, Suh W, Han SB. Seasonal epidemiological and clinical characteristics of pediatric patients with human parainfluenza virus infection by serotype: a retrospective study. Virol J. 2022;19(1):141. doi: 10.1186/s12985-022-01875-2
  • Piechotta V, Siemens W, Thielemann I, et al. Safety and effectiveness of vaccines against COVID-19 in children aged 5-11 years: a systematic review and meta-analysis. Lancet Child Adolesc Health. 2023;7(6):379–391. doi: 10.1016/S2352-4642(23)00078-0
  • Moulia DL, Wallace M, Roper LE, et al. Interim Recommendations for use of Bivalent mRNA COVID-19 vaccines for Persons aged ≥6 months - United States, April 2023. MMWR Morb Mortal Wkly Rep. 2023;72(24):657–662. doi: 10.15585/mmwr.mm7224a3
  • Nguyen KH, Levisohn A, McChesney C, et al. Disparities in child and adolescent COVID-19 vaccination coverage and parental intent toward vaccinations for their children and adolescents. Ann Med. 2023;55(1):2232818. doi: 10.1080/07853890.2023.2232818
  • Jeon J, Chin B. Treatment Options for patients with Mild-to-Moderate coronavirus disease 2019 in Korea. J Korean Med Sci. 2022;37(48). doi: 10.3346/jkms.2022.37.e352

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