Serum uric acid to high-density lipoprotein cholesterol ratio is a promising marker for identifying metabolic syndrome in nondiabetic Chinese men

References

• Saklayen MG. The global epidemic of the metabolic syndrome. Curr Hypertens Rep. 2018 Feb 26;20(2):12. doi: 10.1007/s11906-018-0812-z
   PubMed Web of Science ®Google Scholar
• Lemieux I, Despres JP. Metabolic syndrome: past, present and future. Nutrients. 2020 Nov 14;12(11):3501. doi: 10.3390/nu12113501
   PubMed Web of Science ®Google Scholar
• Yu W, Cheng JD. Uric acid and cardiovascular disease: an update from molecular mechanism to clinical perspective. Front Pharmacol. 2020;11:582680. doi: 10.3389/fphar.2020.582680
   PubMed Web of Science ®Google Scholar
• Saito Y, Tanaka A, Node K, et al. Uric acid and cardiovascular disease: a clinical review. J Cardiol. 2021 Jul;78(1):51–57. doi: 10.1016/j.jjcc.2020.12.013
   PubMed Web of Science ®Google Scholar
• Chen S, Wu N, Yu C, et al. Association between baseline and changes in serum uric acid and incident metabolic syndrome: a nation-wide cohort study and updated meta-analysis. Nutr Metab (Lond). 2021 Jun 9;18(1):59. doi: 10.1186/s12986-021-00584-x
   PubMed Web of Science ®Google Scholar
• Ali N, Miah R, Hasan M, et al. Association between serum uric acid and metabolic syndrome: a cross-sectional study in Bangladeshi adults. Sci Rep. 2020 May 12;10(1):7841. doi: 10.1038/s41598-020-64884-7
   PubMed Web of Science ®Google Scholar
• Liu Y, Fan Y, Liu Q, et al. Sex-specific association of serum uric acid dynamics with the incidence of metabolic syndrome in a health check-up Chinese population: a prospective cohort study. BMJ Open. 2020 Jul 2;10(7):e035289. doi: 10.1136/bmjopen-2019-035289
   PubMed Web of Science ®Google Scholar
• Casula M, Colpani O, Xie S, et al. HDL in atherosclerotic cardiovascular disease: in search of a role. Cells. 2021 Jul 23;10(8):1869. doi: 10.3390/cells10081869
   PubMed Web of Science ®Google Scholar
• Kocak MZ, Aktas G, Erkus E, et al. Serum uric acid to HDL-cholesterol ratio is a strong predictor of metabolic syndrome in type 2 diabetes mellitus. Rev Assoc Med Bras. 2019 Jan;65(1):9–15. doi: 10.1590/1806-9282.65.1.9
   PubMed Web of Science ®Google Scholar
• Xuan Y, Zhang W, Wang Y, et al. Association between uric acid to HDL cholesterol ratio and diabetic complications in men and postmenopausal women. Diabetes Metab Syndr Obes. 2023;16:167–177. doi: 10.2147/DMSO.S387726
   PubMed Web of Science ®Google Scholar
• Aktas G, Yilmaz S, Kantarci DB, et al. Is serum uric acid-to-HDL cholesterol ratio elevation associated with diabetic kidney injury? Postgrad Med. 2023 Jun;135(5):519–523. doi: 10.1080/00325481.2023.2214058
   PubMed Web of Science ®Google Scholar
• Sun H, Su H, Zheng R, et al. Serum uric acid to high‑density lipoprotein cholesterol ratio is associated with visceral fat in patients with type 2 diabetes. Diabetes Metab Syndr Obes. 2023;16:959–967. doi: 10.2147/DMSO.S403895
   PubMed Web of Science ®Google Scholar
• Aktas G, Kocak MZ, Bilgin S, et al. Uric acid to HDL cholesterol ratio is a strong predictor of diabetic control in men with type 2 diabetes mellitus. Aging Male. 2020 Dec;23(5):1098–1102. doi: 10.1080/13685538.2019.1678126
   PubMed Web of Science ®Google Scholar
• Yazdi F, Baghaei MH, Baniasad A, et al. Investigating the relationship between serum uric acid to high-density lipoprotein ratio and metabolic syndrome. Endocrinol Diabetes Metab. 2022 Jan;5(1):e00311. doi: 10.1002/edm2.311
   PubMedGoogle Scholar
• Zhang YN, Wang QQ, Chen YS, et al. Association between serum uric acid to HDL-Cholesterol ratio and nonalcoholic fatty liver disease in lean Chinese adults. Int J Endocrinol. 2020;2020:5953461. doi: 10.1155/2020/5953461
   PubMed Web of Science ®Google Scholar
• Xie Y, Huang K, Zhang X, et al. Association of serum uric acid-to-high-density lipoprotein cholesterol ratio with non-alcoholic fatty liver disease in American adults: a population-based analysis. Front Med. 2023;10:1164096. doi: 10.3389/fmed.2023.1164096
   Web of Science ®Google Scholar
• Kotronen A, Yki-Jarvinen H. Fatty liver: a novel component of the metabolic syndrome. Arterioscler Thromb Vasc Biol. 2008 Jan;28(1):27–38. doi: 10.1161/ATVBAHA.107.147538
   PubMed Web of Science ®Google Scholar
• Yoon H, Yoon YS, Kim SG, et al. Relationship between metabolic syndrome and metabolic syndrome score with beta-cell function by gender in non-diabetic Korean populations. Endocr Res. 2019 Aug;44(3):71–80. doi: 10.1080/07435800.2018.1524476
   PubMed Web of Science ®Google Scholar
• Esteghamati A, Zandieh A, Khalilzadeh O, et al. Clustering of metabolic syndrome components in a middle Eastern diabetic and non-diabetic population. Diabetol Metab Syndr. 2010 Jun 8;2(1):36. doi: 10.1186/1758-5996-2-36
   PubMedGoogle Scholar
• Leite ML, Nicolosi A. Dietary patterns and metabolic syndrome factors in a non-diabetic Italian population. Public Health Nutr. 2009 Sep;12(9):1494–1503. doi: 10.1017/S1368980008004539
   PubMed Web of Science ®Google Scholar
• Johns BR, Pao AC, Kim SH. Metabolic syndrome, insulin resistance and kidney function in non-diabetic individuals. Nephrol Dial Transplant. 2012 Apr;27(4):1410–1415. doi: 10.1093/ndt/gfr498
   PubMed Web of Science ®Google Scholar
• Yang SH, Dou KF, Song WJ. Prevalence of diabetes among men and women in China. N Engl J Med. 2010 Jun 24;362(25):2425–2426. author reply 2426. 10.1056/NEJMoa0908292
   PubMedGoogle Scholar
• Yang W, Xiao J, Yang Z, et al. Serum lipids and lipoproteins in Chinese men and women. Circulation. 2012 May 8;125(18):2212–2221. doi: 10.1161/CIRCULATIONAHA.111.065904
   PubMed Web of Science ®Google Scholar
• Park JH, Jo YI, Lee JH. Renal effects of uric acid: hyperuricemia and hypouricemia. Korean J Intern Med. 2020 Nov;35(6):1291–1304. doi: 10.3904/kjim.2020.410
   PubMed Web of Science ®Google Scholar
• Alberti KG, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009 Oct 20;120(16):1640–1645. doi: 10.1161/CIRCULATIONAHA.109.192644
   PubMed Web of Science ®Google Scholar
• Jia W, Weng J, Zhu D, et al. Standards of medical care for type 2 diabetes in China 2019. Diabetes Metab Res Rev. 2019 Sep;35(6):e3158. doi: 10.1002/dmrr.3158
   PubMed Web of Science ®Google Scholar
• Sun Y, Zhang H, Tian W, et al. Association between serum uric acid levels and coronary artery disease in different age and gender: a cross-sectional study. Aging Clin Exp Res. 2019 Dec;31(12):1783–1790. doi: 10.1007/s40520-019-01137-2
   PubMed Web of Science ®Google Scholar
• Zitt E, Fischer A, Lhotta K, et al. Sex- and age-specific variations, temporal trends and metabolic determinants of serum uric acid concentrations in a large population-based Austrian cohort. Sci Rep. 2020 May 5;10(1):7578. doi: 10.1038/s41598-020-64587-z
   PubMed Web of Science ®Google Scholar
• Chen YL, Li H, Li S, et al. Prevalence of and risk factors for metabolic associated fatty liver disease in an urban population in China: a cross-sectional comparative study. BMC Gastroenterol. 2021 May 10;21(1):212. doi: 10.1186/s12876-021-01782-w
   PubMed Web of Science ®Google Scholar
• Xiang Y, Huang G, Zhou W, et al. Prevalence of metabolic syndrome (MetS) in Chinese subjects gradually increased with impaired glucose homeostasis: a multicenter, clinical based, cross-sectional study. BMC Public Health. 2012 Aug 20;12(1):675. doi: 10.1186/1471-2458-12-675
   PubMedGoogle Scholar
• Aktas G, Khalid A, Kurtkulagi O, et al. Poorly controlled hypertension is associated with elevated serum uric acid to HDL-cholesterol ratio: a cross-sectional cohort study. Postgrad Med. 2022 Apr;134(3):297–302. doi: 10.1080/00325481.2022.2039007
   PubMed Web of Science ®Google Scholar
• Kurtkulagi O, Tel BMA, Kahveci G, et al. Hashimoto’s thyroiditis is associated with elevated serum uric acid to high density lipoprotein-cholesterol ratio. Rom J Intern Med. 2021 Dec 1;59(4):403–408. doi: 10.2478/rjim-2021-0023
   PubMed Web of Science ®Google Scholar
• Silveira Rossi JL, Barbalho SM, de Araujo R R, et al. Metabolic syndrome and cardiovascular diseases: going beyond traditional risk factors. Diabetes Metab Res Rev. 2022 Mar;38(3):e3502. doi: 10.1002/dmrr.3502
   PubMed Web of Science ®Google Scholar
• Copur S, Demiray A, Kanbay M. Uric acid in metabolic syndrome: does uric acid have a definitive role? Eur J Intern Med. 2022 Sep;103:4–12. doi: 10.1016/j.ejim.2022.04.022
   PubMed Web of Science ®Google Scholar
• Cho KH. The current status of research on high-density lipoproteins (HDL): a paradigm shift from HDL quantity to HDL quality and HDL functionality. Int J Mol Sci. 2022 Apr 2;23(7):3967. doi: 10.3390/ijms23073967
   PubMed Web of Science ®Google Scholar
• Yoon H, Lee JH, Gi MY, et al. Relationship between metabolic syndrome and Beta-Cell function in nondiabetic Korean premenopausal and postmenopausal women: 2015 Korean National Health and Nutrition Examination Survey. Metab Syndr Relat Disord. 2020 Feb;18(1):39–46. doi: 10.1089/met.2019.0087
   PubMed Web of Science ®Google Scholar
• Yang W, Lu J, Weng J, et al. Prevalence of diabetes among men and women in China. N Engl J Med. 2010 Mar 25;362(12):1090–1101. doi: 10.1056/NEJMoa0908292
   PubMed Web of Science ®Google Scholar
• Xu Y, Wang L, He J, et al. Prevalence and control of diabetes in Chinese adults. JAMA. 2013 Sep 4;310(9):948–959. doi: 10.1001/jama.2013.168118
   PubMed Web of Science ®Google Scholar
• Wang L, Gao P, Zhang M, et al. Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013. JAMA. 2017 Jun 27;317(24):2515–2523. doi: 10.1001/jama.2017.7596
   PubMed Web of Science ®Google Scholar
• Li Y, Teng D, Shi X, et al. Prevalence of diabetes recorded in mainland China using 2018 diagnostic criteria from the American Diabetes Association: national cross sectional study. BMJ. 2020 Apr 28;369:m997. doi: 10.1136/bmj.m997
   PubMedGoogle Scholar
• Shan R, Ning Y, Ma Y, et al. Incidence and risk factors of hyperuricemia among 2.5 million Chinese adults during the years 2017–2018. Int J Environ Res Public Health. 2021 Feb 28;18(5):2360. doi: 10.3390/ijerph18052360
   PubMed Web of Science ®Google Scholar
• Cheng F, Yin X, Duan W, et al. Different-shaped curves for serum uric acid with and without diabetes: results from China health and retirement longitudinal study. J Diabetes. 2019 Jun;11(6):431–439. doi: 10.1111/1753-0407.12863
   PubMed Web of Science ®Google Scholar
• Qi J, Dai X, Zhou B, et al. Association between lipid profiles and serum urate: a cross-sectional study in Southwestern China. Int J Endocrinol. 2021;2021:1–9. doi: 10.1155/2021/2741131
   Web of Science ®Google Scholar
• Wallace IR, McKinley MC, Bell PM, et al. Sex hormone binding globulin and insulin resistance. Clin Endocrinol (Oxf). 2013 Mar;78(3):321–329. doi: 10.1111/cen.12086
   PubMed Web of Science ®Google Scholar
• Hu CH, Zhang M, Zhang X, et al. Relationship between eating behavior and obesity among Chinese adults. Zhonghua Liu Xing Bing Xue Za Zhi. 2020 Aug 10;41(8):1296–1302. doi: 10.3760/cma.j.cn112338-20191225-00915
   PubMedGoogle Scholar
• Zang J, Luo B, Wang Y, et al. Eating out-of-home in adult residents in Shanghai and the nutritional differences among dining places. Nutrients. 2018 Jul 23;10(7):951. doi: 10.3390/nu10070951
   PubMed Web of Science ®Google Scholar
• Vandevijvere S, Lachat C, Kolsteren P, et al. Eating out of home in Belgium: current situation and policy implications. Br J Nutr. 2009 Sep;102(6):921–928. doi: 10.1017/S0007114509311745
   PubMed Web of Science ®Google Scholar